SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ho4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8I_A_RO7A1_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	5ho4	HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2/B1 (Homo sapiens)	4 / 7	LEU A 171 LEU A 47 VAL A 75 LEU A 28	None	0.90A	3g8iA-5ho4A: undetectable	3g8iA-5ho4A: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OT2_A_NPSA602_1 (SERUM ALBUMIN)	5ho4	HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2/B1 (Homo sapiens)	4 / 6	ARG A 95 ALA A 78 ASP A 164 SER A 71	None	1.10A	4ot2A-5ho4A: undetectable	4ot2A-5ho4A: 15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AYF_A_C7HA402_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	5ho4	HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2/B1 (Homo sapiens)	4 / 5	TYR A 41 GLY A 26 TYR A 40 GLY A 88	None A B 1 ( 3.6A) None None	0.92A	5ayfA-5ho4A: undetectable	5ayfA-5ho4A: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_A_P06A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5ho4	HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2/B1 (Homo sapiens)	4 / 7	ILE A 25 GLY A 65 PHE A 20 ASP A 49	None None None G B 4 ( 2.9A)	0.64A	5hieA-5ho4A: undetectable	5hieA-5ho4A: 19.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3G8I_A_RO7A1_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA","5ho4","HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2\/B1","Homo sapiens",4,"LEU A 171;LEU A  47;VAL A  75;LEU A  28","None","0.90A","3g8iA-5ho4A:undetectable","3g8iA-5ho4A:21.37"],["4OT2_A_NPSA602_1","SERUM ALBUMIN","5ho4","HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2\/B1","Homo sapiens",4,"ARG A  95;ALA A  78;ASP A 164;SER A  71","None","1.10A","4ot2A-5ho4A:undetectable","4ot2A-5ho4A:15.03"],["5AYF_A_C7HA402_1","HISTONE-LYSINE N-METHYLTRANSFERASE SETD7","5ho4","HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2\/B1","Homo sapiens",4,"TYR A  41;GLY A  26;TYR A  40;GLY A  88","None;  A B   1 ( 3.6A);None;None","0.92A","5ayfA-5ho4A:undetectable","5ayfA-5ho4A:18.94"],["5HIE_A_P06A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5ho4","HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2\/B1","Homo sapiens",4,"ILE A  25;GLY A  65;PHE A  20;ASP A  49","None;None;None;  G B   4 ( 2.9A)","0.64A","5hieA-5ho4A:undetectable","5hieA-5ho4A:19.02"]]