SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hop'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		5 / 12 THR A 132
LEU A 131
ILE A 130
VAL A 159
CYH A 120
 None
 1.31A 1wsvB-5hopA:
undetectable		 1wsvB-5hopA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		4 / 7 THR A 136
ASP A  84
SER A  76
LEU A 171
 None
 0.96A 2hdnE-5hopA:
undetectable
2hdnF-5hopA:
undetectable
2hdnH-5hopA:
undetectable		 2hdnE-5hopA:
14.47
2hdnF-5hopA:
21.49
2hdnH-5hopA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		4 / 7 SER A  76
LEU A 171
THR A 136
ASP A  84
 None
 0.97A 2hdnF-5hopA:
undetectable
2hdnG-5hopA:
undetectable
2hdnH-5hopA:
undetectable		 2hdnF-5hopA:
21.49
2hdnG-5hopA:
14.47
2hdnH-5hopA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		4 / 5 LEU A 171
ALA A 190
LEU A 193
MET A 160
 None
 1.23A 2oaxA-5hopA:
undetectable		 2oaxA-5hopA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		4 / 8 ILE A  22
ASN A  19
ALA A 233
GLU A  16
 None
 0.90A 2x0pA-5hopA:
undetectable		 2x0pA-5hopA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLU A 229
HIS A  13
GLU A  16
 None
 0.62A 2x45B-5hopA:
undetectable		 2x45B-5hopA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLU A 229
HIS A  13
GLU A  16
 None
 0.65A 2x45C-5hopA:
undetectable		 2x45C-5hopA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		5 / 12 PHE A   4
LEU A   7
GLU A  40
ALA A  96
PHE A 150
 None
 1.47A 3apwB-5hopA:
undetectable		 3apwB-5hopA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		3 / 3 TYR A  54
THR A 103
GLU A  60
 None
 0.82A 4df3A-5hopA:
undetectable		 4df3A-5hopA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		3 / 3 TYR A  54
THR A 103
GLU A  60
 None
 0.81A 4df3B-5hopA:
undetectable		 4df3B-5hopA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		4 / 4 LEU A 196
ARG A 235
ILE A 230
PHE A 234
 None
 1.28A 5kirB-5hopA:
undetectable		 5kirB-5hopA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		5 / 10 PHE A 234
LEU A 196
ALA A 192
LEU A 211
GLU A 218
 None
 1.25A 5y7pG-5hopA:
undetectable		 5y7pG-5hopA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		4 / 6 VAL A  62
LEU A  66
LEU A  97
TYR A  54
 None
 0.98A 6f6sA-5hopA:
undetectable
6f6sB-5hopA:
undetectable		 6f6sA-5hopA:
15.32
6f6sB-5hopA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5hop LMO0182 PROTEIN
(Listeria
monocytogenes) 		4 / 8 TYR A  94
ILE A 113
ARG A 117
ASP A 157
 None
 1.04A 6hu9a-5hopA:
undetectable
6hu9e-5hopA:
1.8		 6hu9a-5hopA:
19.09
6hu9e-5hopA:
20.88