SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5hou CELLULAR TUMOR
ANTIGEN
P53,CREB-BINDING
PROTEIN FUSION
PROTEIN
(Homo
sapiens;
Mus
musculus) 		4 / 6 ILE A1050
GLN A3356
VAL A3390
SER A3410
 None
 1.08A 1rs7B-5houA:
undetectable		 1rs7B-5houA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5hou CELLULAR TUMOR
ANTIGEN
P53,CREB-BINDING
PROTEIN FUSION
PROTEIN
(Homo
sapiens;
Mus
musculus) 		4 / 6 ILE A1050
GLN A3356
VAL A3390
SER A3410
 None
 1.04A 4kcnA-5houA:
undetectable		 4kcnA-5houA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 5hou CELLULAR TUMOR
ANTIGEN
P53,CREB-BINDING
PROTEIN FUSION
PROTEIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 CYH A3366
LYS A3365
HIS A3364
 ZN  A5001 ( 2.2A)
None
None
 0.97A 5js5A-5houA:
undetectable		 5js5A-5houA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 5hou CELLULAR TUMOR
ANTIGEN
P53,CREB-BINDING
PROTEIN FUSION
PROTEIN
(Homo
sapiens;
Mus
musculus) 		5 / 9 LEU A3361
LEU A3432
ILE A3415
MET A3387
LEU A3391
 None
 1.24A 5og9A-5houA:
undetectable		 5og9A-5houA:
17.80