SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hpd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4L_D_DCFD1853_2 (ADENOSINE DEAMINASE)	5hpd	CREB-BINDING PROTEIN,CELLULAR TUMOR ANTIGEN P53 FUSION PROTEIN (Homo sapiens; Mus musculus)	4 / 4	HIS A1805 LEU A3025 LEU A3022 LEU A3014	ZN A 202 ( 3.3A) None None None	1.14A	1a4lD-5hpdA: undetectable	1a4lD-5hpdA: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD4_B_CHDB927_0 (FERROCHELATASE)	5hpd	CREB-BINDING PROTEIN,CELLULAR TUMOR ANTIGEN P53 FUSION PROTEIN (Homo sapiens; Mus musculus)	3 / 3	LEU A1793 PRO A1794 ARG A1775	None	0.62A	2qd4B-5hpdA: undetectable	2qd4B-5hpdA: 17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_E_ACTE503_0 (RNA POLYMERASE 3D-POL)	5hpd	CREB-BINDING PROTEIN,CELLULAR TUMOR ANTIGEN P53 FUSION PROTEIN (Homo sapiens; Mus musculus)	4 / 4	MET A1799 SER A1779 LEU A1826 CYH A1776	None	1.43A	4k50E-5hpdA: undetectable	4k50E-5hpdA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_M_ACTM501_0 (RNA POLYMERASE 3D-POL)	5hpd	CREB-BINDING PROTEIN,CELLULAR TUMOR ANTIGEN P53 FUSION PROTEIN (Homo sapiens; Mus musculus)	4 / 4	MET A1799 SER A1779 LEU A1826 CYH A1776	None	1.45A	4k50M-5hpdA: 0.8	4k50M-5hpdA: 14.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4L_D_DCFD1853_2","ADENOSINE DEAMINASE","5hpd","CREB-BINDING PROTEIN,CELLULAR TUMOR ANTIGEN P53 FUSION PROTEIN","Homo sapiens;Mus musculus",4,"HIS A1805;LEU A3025;LEU A3022;LEU A3014"," ZN A 202 ( 3.3A);None;None;None","1.14A","1a4lD-5hpdA:undetectable","1a4lD-5hpdA:17.42"],["2QD4_B_CHDB927_0","FERROCHELATASE","5hpd","CREB-BINDING PROTEIN,CELLULAR TUMOR ANTIGEN P53 FUSION PROTEIN","Homo sapiens;Mus musculus",3,"LEU A1793;PRO A1794;ARG A1775","None","0.62A","2qd4B-5hpdA:undetectable","2qd4B-5hpdA:17.55"],["4K50_E_ACTE503_0","RNA POLYMERASE 3D-POL","5hpd","CREB-BINDING PROTEIN,CELLULAR TUMOR ANTIGEN P53 FUSION PROTEIN","Homo sapiens;Mus musculus",4,"MET A1799;SER A1779;LEU A1826;CYH A1776","None","1.43A","4k50E-5hpdA:undetectable","4k50E-5hpdA:14.29"],["4K50_M_ACTM501_0","RNA POLYMERASE 3D-POL","5hpd","CREB-BINDING PROTEIN,CELLULAR TUMOR ANTIGEN P53 FUSION PROTEIN","Homo sapiens;Mus musculus",4,"MET A1799;SER A1779;LEU A1826;CYH A1776","None","1.45A","4k50M-5hpdA:0.8","4k50M-5hpdA:14.29"]]