SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hpg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 5hpg PLASMINOGEN
(Homo
sapiens) 		4 / 7 ASP A  57
TRP A  62
TYR A  64
TYR A  72
 None
 0.72A 1cebA-5hpgA:
16.9		 1cebA-5hpgA:
54.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 5hpg PLASMINOGEN
(Homo
sapiens) 		3 / 3 GLN A  23
HIS A  31
PRO A  68
 None
 0.92A 1d8cA-5hpgA:
undetectable		 1d8cA-5hpgA:
8.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BVV_A_CPFA1081_1
(APOLIPOPROTEIN(A))		 5hpg PLASMINOGEN
(Homo
sapiens) 		6 / 9 HIS A  33
SER A  34
ASP A  57
TRP A  62
TYR A  64
LEU A  71
 None
 0.68A 4bvvA-5hpgA:
17.1		 4bvvA-5hpgA:
82.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		 5hpg PLASMINOGEN
(Homo
sapiens) 		5 / 10 TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
 None
 1.48A 6mb9D-5hpgA:
undetectable		 6mb9D-5hpgA:
17.78