SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hpn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.15A 1gtnB-5hpnA:
undetectable
1gtnC-5hpnA:
undetectable		 1gtnB-5hpnA:
23.16
1gtnC-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.12A 1gtnH-5hpnA:
undetectable
1gtnI-5hpnA:
undetectable		 1gtnH-5hpnA:
23.16
1gtnI-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 9 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.18A 1gtnQ-5hpnA:
undetectable
1gtnR-5hpnA:
undetectable		 1gtnQ-5hpnA:
23.16
1gtnR-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.15A 1gtnU-5hpnA:
undetectable
1gtnV-5hpnA:
undetectable		 1gtnU-5hpnA:
23.16
1gtnV-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.17A 1utdT-5hpnA:
undetectable
1utdU-5hpnA:
undetectable		 1utdT-5hpnA:
23.16
1utdU-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.13A 5eeuF-5hpnA:
undetectable
5eeuG-5hpnA:
undetectable		 5eeuF-5hpnA:
23.16
5eeuG-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 12 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.15A 5eeuI-5hpnA:
undetectable
5eeuJ-5hpnA:
undetectable		 5eeuI-5hpnA:
23.16
5eeuJ-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.14A 5eeuO-5hpnA:
undetectable
5eeuP-5hpnA:
undetectable		 5eeuO-5hpnA:
23.16
5eeuP-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.15A 5eeuQ-5hpnA:
undetectable
5eeuR-5hpnA:
undetectable		 5eeuQ-5hpnA:
23.16
5eeuR-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.14A 5eevF-5hpnA:
undetectable
5eevG-5hpnA:
undetectable		 5eevF-5hpnA:
23.16
5eevG-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 12 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.15A 5eevI-5hpnA:
undetectable
5eevJ-5hpnA:
undetectable		 5eevI-5hpnA:
23.16
5eevJ-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.15A 5eevO-5hpnA:
undetectable
5eevP-5hpnA:
undetectable		 5eevO-5hpnA:
23.16
5eevP-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.15A 5eevQ-5hpnA:
undetectable
5eevR-5hpnA:
undetectable		 5eevQ-5hpnA:
23.16
5eevR-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.14A 5eewF-5hpnA:
undetectable
5eewG-5hpnA:
undetectable		 5eewF-5hpnA:
23.16
5eewG-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 12 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.15A 5eewI-5hpnA:
undetectable
5eewJ-5hpnA:
undetectable		 5eewI-5hpnA:
23.16
5eewJ-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.15A 5eewO-5hpnA:
undetectable
5eewP-5hpnA:
undetectable		 5eewO-5hpnA:
23.16
5eewP-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.15A 5eewQ-5hpnA:
undetectable
5eewR-5hpnA:
undetectable		 5eewQ-5hpnA:
23.16
5eewR-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.14A 5eexF-5hpnA:
undetectable
5eexG-5hpnA:
undetectable		 5eexF-5hpnA:
23.16
5eexG-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.14A 5eexO-5hpnA:
undetectable
5eexP-5hpnA:
undetectable		 5eexO-5hpnA:
23.16
5eexP-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.13A 5eeyF-5hpnA:
undetectable
5eeyG-5hpnA:
undetectable		 5eeyF-5hpnA:
23.16
5eeyG-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.14A 5eeyO-5hpnA:
undetectable
5eeyP-5hpnA:
undetectable		 5eeyO-5hpnA:
23.16
5eeyP-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.13A 5eezF-5hpnA:
undetectable
5eezG-5hpnA:
undetectable		 5eezF-5hpnA:
23.16
5eezG-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.14A 5eezO-5hpnA:
undetectable
5eezP-5hpnA:
undetectable		 5eezO-5hpnA:
23.16
5eezP-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.14A 5ef0F-5hpnA:
undetectable
5ef0G-5hpnA:
undetectable		 5ef0F-5hpnA:
23.16
5ef0G-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.14A 5ef0O-5hpnA:
undetectable
5ef0P-5hpnA:
undetectable		 5ef0O-5hpnA:
23.16
5ef0P-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.14A 5ef1F-5hpnA:
undetectable
5ef1G-5hpnA:
undetectable		 5ef1F-5hpnA:
23.16
5ef1G-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.15A 5ef1O-5hpnA:
undetectable
5ef1P-5hpnA:
undetectable		 5ef1O-5hpnA:
23.16
5ef1P-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.13A 5ef2F-5hpnA:
undetectable
5ef2G-5hpnA:
undetectable		 5ef2F-5hpnA:
23.16
5ef2G-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.14A 5ef2O-5hpnA:
undetectable
5ef2P-5hpnA:
undetectable		 5ef2O-5hpnA:
23.16
5ef2P-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 SER A  48
ALA A  49
GLY A  28
ALA A  74
THR A  79
 None
 1.13A 5ef3F-5hpnA:
undetectable
5ef3G-5hpnA:
undetectable		 5ef3F-5hpnA:
23.16
5ef3G-5hpnA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hpn PERMUTED PDUA
(synthetic
construct) 		5 / 10 GLY A  28
ALA A  74
THR A  79
SER A  48
ALA A  49
 None
 1.14A 5ef3O-5hpnA:
undetectable
5ef3P-5hpnA:
undetectable		 5ef3O-5hpnA:
23.16
5ef3P-5hpnA:
23.16