SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hpz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5hpz WATER-SOLUBLE
CHLOROPHYLL PROTEIN
(Brassicaceae) 		5 / 12 ILE A 113
PHE A  82
PRO A  54
PHE A  19
ILE A  45
 None
 0.92A 1cd2A-5hpzA:
undetectable		 1cd2A-5hpzA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5hpz WATER-SOLUBLE
CHLOROPHYLL PROTEIN
(Brassicaceae) 		4 / 5 THR A 166
THR A 143
GLU A 127
THR A  74
 None
 1.44A 1d4fB-5hpzA:
undetectable		 1d4fB-5hpzA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5hpz WATER-SOLUBLE
CHLOROPHYLL PROTEIN
(Brassicaceae) 		5 / 12 LEU A 157
LEU A 167
ILE A 113
SER A  25
VAL A  58
 None
 1.18A 2po7A-5hpzA:
undetectable		 2po7A-5hpzA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 5hpz WATER-SOLUBLE
CHLOROPHYLL PROTEIN
(Brassicaceae) 		4 / 5 LEU A 157
ILE A  20
ILE A 111
GLY A 145
 None
 0.95A 3bufA-5hpzA:
undetectable		 3bufA-5hpzA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5hpz WATER-SOLUBLE
CHLOROPHYLL PROTEIN
(Brassicaceae) 		5 / 10 VAL A 169
PHE A 171
LEU A 137
THR A 143
THR A 138
 None
 1.43A 3dazA-5hpzA:
undetectable		 3dazA-5hpzA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 5hpz WATER-SOLUBLE
CHLOROPHYLL PROTEIN
(Brassicaceae) 		4 / 8 TYR A  18
ILE A  72
ILE A 126
ILE A  80
 None
 0.82A 3p4wC-5hpzA:
undetectable		 3p4wC-5hpzA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 5hpz WATER-SOLUBLE
CHLOROPHYLL PROTEIN
(Brassicaceae) 		5 / 10 VAL A 169
PHE A 171
LEU A 137
THR A 143
THR A 138
 None
 1.45A 3v2mA-5hpzA:
undetectable		 3v2mA-5hpzA:
18.53