SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 7 HIS A 286
HIS A 322
HIS A 288
THR A 392
KCX  A 192 ( 3.5A)
KCX  A 192 (-3.8A)
CAP  A 500 (-3.9A)
KCX  A 192 ( 3.1A)
0.91A 1am6A-5hqlA:
undetectable
1am6A-5hqlA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 4 GLY A 163
ASP A 189
GLY A 159
THR A 365
None
1.00A 1hxbB-5hqlA:
undetectable
1hxbB-5hqlA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 12 THR A 392
ILE A 321
GLY A 320
THR A 364
ALA A 260
KCX  A 192 ( 3.1A)
None
None
None
None
0.92A 1nv8A-5hqlA:
2.0
1nv8A-5hqlA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 12 THR A 392
ILE A 321
GLY A 320
THR A 364
ALA A 260
KCX  A 192 ( 3.1A)
None
None
None
None
0.91A 1nv8B-5hqlA:
undetectable
1nv8B-5hqlA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 9 ALA A 219
LEU A 186
GLY A 187
PHE A 184
GLY A 404
None
1.49A 1ru9H-5hqlA:
undetectable
1ru9L-5hqlA:
undetectable
1ru9H-5hqlA:
19.52
1ru9L-5hqlA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 12 THR A 392
GLY A 394
GLY A 395
GLY A 371
PHE A 190
KCX  A 192 ( 3.1A)
CAP  A 500 (-3.4A)
CAP  A 500 (-3.7A)
CAP  A 500 (-3.4A)
KCX  A 192 ( 4.0A)
0.85A 1wg8A-5hqlA:
undetectable
1wg8A-5hqlA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 12 THR A 392
GLY A 394
GLY A 395
GLY A 371
PHE A 190
KCX  A 192 ( 3.1A)
CAP  A 500 (-3.4A)
CAP  A 500 (-3.7A)
CAP  A 500 (-3.4A)
KCX  A 192 ( 4.0A)
0.85A 1wg8B-5hqlA:
undetectable
1wg8B-5hqlA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 12 ALA A 215
ALA A 405
ALA A 408
ILE A 191
LEU A 151
None
None
None
KCX  A 192 ( 3.8A)
None
1.11A 2nyrA-5hqlA:
undetectable
2nyrA-5hqlA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_H_BEZH2001_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 10 PHE A 177
GLN A 197
GLY A 198
ASN A 193
PHE A 231
None
None
None
KCX  A 192 ( 4.9A)
None
1.33A 2ok6A-5hqlA:
undetectable
2ok6H-5hqlA:
undetectable
2ok6A-5hqlA:
22.52
2ok6H-5hqlA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 10 ASP A 194
SER A 310
ILE A 321
ILE A 340
GLY A 370
MG  A 501 ( 2.9A)
None
None
None
CAP  A 500 (-3.0A)
1.28A 2v0mA-5hqlA:
undetectable
2v0mA-5hqlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 5 PHE A 252
PHE A 190
PHE A 231
ILE A 144
None
KCX  A 192 ( 4.0A)
None
None
1.25A 2v0mD-5hqlA:
undetectable
2v0mD-5hqlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 11 HIS A 286
HIS A 322
HIS A 288
PHE A 229
THR A 392
KCX  A 192 ( 3.5A)
KCX  A 192 (-3.8A)
CAP  A 500 (-3.9A)
KCX  A 192 ( 4.3A)
KCX  A 192 ( 3.1A)
1.10A 3hs4A-5hqlA:
undetectable
3hs4A-5hqlA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 4 GLY A 163
ASP A 189
GLY A 159
THR A 365
None
1.04A 3k4vC-5hqlA:
undetectable
3k4vC-5hqlA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 5 ILE A 367
THR A 365
THR A 364
SER A 319
None
1.23A 3snfA-5hqlA:
undetectable
3snfA-5hqlA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 10 HIS A 286
HIS A 322
HIS A 288
PHE A 229
THR A 392
KCX  A 192 ( 3.5A)
KCX  A 192 (-3.8A)
CAP  A 500 (-3.9A)
KCX  A 192 ( 4.3A)
KCX  A 192 ( 3.1A)
1.11A 3v2mA-5hqlA:
undetectable
3v2mA-5hqlA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 7 SER A  50
GLY A  53
THR A  54
THR A 107
None
0.74A 4ac9C-5hqlA:
2.4
4ac9C-5hqlA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 7 SER A  50
GLY A  53
THR A  54
THR A 107
None
0.75A 4acaC-5hqlA:
2.4
4acaC-5hqlA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
3 / 3 LYS A  83
LEU A  81
ALA A  27
None
0.66A 4iizA-5hqlA:
undetectable
4iizA-5hqlA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 8 HIS A 286
HIS A 322
HIS A 288
THR A 392
KCX  A 192 ( 3.5A)
KCX  A 192 (-3.8A)
CAP  A 500 (-3.9A)
KCX  A 192 ( 3.1A)
0.91A 4n16A-5hqlA:
undetectable
4n16A-5hqlA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 6 ILE A 165
ASP A 194
GLY A 370
HIS A 288
KCX  A 192 (-3.7A)
MG  A 501 ( 2.9A)
CAP  A 500 (-3.0A)
CAP  A 500 (-3.9A)
0.88A 4oltA-5hqlA:
undetectable
4oltA-5hqlA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 6 ILE A 165
ASP A 194
GLY A 370
HIS A 288
KCX  A 192 (-3.7A)
MG  A 501 ( 2.9A)
CAP  A 500 (-3.0A)
CAP  A 500 (-3.9A)
0.87A 4oltB-5hqlA:
undetectable
4oltB-5hqlA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
6 / 12 GLY A 188
TYR A 182
THR A 223
GLY A 187
ALA A 405
GLY A 404
None
1.30A 4pm7A-5hqlA:
undetectable
4pm7A-5hqlA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
6 / 12 GLY A 188
TYR A 182
THR A 223
GLY A 187
ALA A 405
GLY A 404
None
1.21A 4pm9A-5hqlA:
undetectable
4pm9A-5hqlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 12 LEU A 147
THR A 392
ILE A 367
HIS A 286
ALA A 260
None
KCX  A 192 ( 3.1A)
None
KCX  A 192 ( 3.5A)
None
1.18A 4rp8C-5hqlA:
undetectable
4rp8C-5hqlA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 12 LEU A 262
ILE A 367
HIS A 322
ALA A 290
ILE A 165
KCX  A 192 ( 4.1A)
None
KCX  A 192 (-3.8A)
None
KCX  A 192 (-3.7A)
1.25A 4rp8C-5hqlA:
undetectable
4rp8C-5hqlA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 12 THR A 251
GLY A 245
ARG A 244
PHE A 231
GLY A 198
None
1.28A 4uinH-5hqlA:
undetectable
4uinL-5hqlA:
undetectable
4uinH-5hqlA:
18.66
4uinL-5hqlA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 7 GLU A  74
TYR A  73
ASP A 126
ALA A  27
None
1.11A 4zz8A-5hqlA:
undetectable
4zz8A-5hqlA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 7 THR A 323
PRO A 366
THR A 364
SER A 310
None
1.23A 5b6iA-5hqlA:
undetectable
5b6iA-5hqlA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 5 PHE A 398
ILE A 191
GLY A 404
ILE A 166
None
KCX  A 192 ( 3.8A)
None
KCX  A 192 ( 4.8A)
0.80A 5dzkB-5hqlA:
2.2
5dzkI-5hqlA:
1.4
5dzkW-5hqlA:
undetectable
5dzkB-5hqlA:
19.52
5dzkI-5hqlA:
18.45
5dzkW-5hqlA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 5 PHE A 398
ILE A 191
GLY A 404
ILE A 166
None
KCX  A 192 ( 3.8A)
None
KCX  A 192 ( 4.8A)
0.84A 5dzkd-5hqlA:
2.4
5dzkk-5hqlA:
1.4
5dzky-5hqlA:
undetectable
5dzkd-5hqlA:
19.52
5dzkk-5hqlA:
18.45
5dzky-5hqlA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 11 HIS A 322
ILE A 367
HIS A 286
SER A 369
ASP A 189
KCX  A 192 (-3.8A)
None
KCX  A 192 ( 3.5A)
CAP  A 500 (-3.3A)
None
1.24A 5z0fA-5hqlA:
undetectable
5z0fB-5hqlA:
undetectable
5z0fA-5hqlA:
9.98
5z0fB-5hqlA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_A_ASCA501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 10 HIS A 286
ILE A 367
HIS A 322
ALA A 290
ILE A 165
KCX  A 192 ( 3.5A)
None
KCX  A 192 (-3.8A)
None
KCX  A 192 (-3.7A)
1.16A 5zovA-5hqlA:
0.0
5zovA-5hqlA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_B_ASCB501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 12 HIS A 286
ILE A 367
HIS A 322
ALA A 290
ILE A 165
KCX  A 192 ( 3.5A)
None
KCX  A 192 (-3.8A)
None
KCX  A 192 (-3.7A)
1.17A 5zovB-5hqlA:
undetectable
5zovB-5hqlA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
4 / 7 ASP A 254
ASN A 255
ALA A 256
GLU A 250
None
0.69A 6ci6A-5hqlA:
undetectable
6ci6A-5hqlA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)
5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Rhodopseudomonas
palustris)
5 / 11 THR A 392
PHE A 190
SER A 230
ALA A 260
ALA A 313
KCX  A 192 ( 3.1A)
KCX  A 192 ( 4.0A)
KCX  A 192 ( 3.9A)
None
None
1.42A 6efnA-5hqlA:
6.0
6efnA-5hqlA:
20.98