SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hrj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_I_ASDI1224_1 (GLUTATHIONE S-TRANSFERASE A3)	5hrj	SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130 (Sus scrofa)	5 / 9	LEU A 479 PRO A 477 LEU A 553 ALA A 510 PHE A 506	None	1.23A	2vcvI-5hrjA: undetectable	2vcvI-5hrjA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_A_W9TA1004_1 (HEMOLYTIC LECTIN CEL-III)	5hrj	SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130 (Sus scrofa)	4 / 5	ASP A 571 GLU A 534 GLY A 533 GLU A 491	None	1.34A	3w9tA-5hrjA: undetectable	3w9tA-5hrjA: 12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z2E_H_TR6H101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B SYMMETRIZED E-SITE DNA)	5hrj	SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130 (Sus scrofa)	3 / 5	GLY A 537 GLY A 499 GLU A 491	None	0.46A	4z2eA-5hrjA: undetectable 4z2eD-5hrjA: undetectable	4z2eA-5hrjA: 12.85 4z2eD-5hrjA: 15.44