SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 5hso UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887
(Mycobacterium
tuberculosis) 		4 / 5 GLU A  37
LEU A  28
LEU A  33
LEU A  35
 None
 1.13A 1np1A-5hsoA:
undetectable		 1np1A-5hsoA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5hso UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887
(Mycobacterium
tuberculosis) 		5 / 11 ALA A  78
LEU A  28
LEU A  31
LEU A 102
LEU A  33
 None
 1.04A 2ceoA-5hsoA:
undetectable		 2ceoA-5hsoA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5hso UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887
(Mycobacterium
tuberculosis) 		5 / 11 THR A  96
ALA A  78
GLY A  49
ALA A  93
SER A  45
 None
 1.18A 2f162-5hsoA:
undetectable		 2f162-5hsoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5hso UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887
(Mycobacterium
tuberculosis) 		5 / 11 THR A  96
ALA A  78
GLY A  49
ALA A  93
SER A  45
 None
 1.17A 2f16N-5hsoA:
undetectable		 2f16N-5hsoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5hso UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887
(Mycobacterium
tuberculosis) 		5 / 10 ALA A  76
LEU A  28
LEU A  31
LEU A 102
LEU A  33
 None
 1.14A 2riwA-5hsoA:
undetectable
2riwB-5hsoA:
undetectable		 2riwA-5hsoA:
15.63
2riwB-5hsoA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5hso UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887
(Mycobacterium
tuberculosis) 		5 / 10 ALA A  78
LEU A  28
LEU A  31
LEU A 102
LEU A  33
 None
 1.00A 2riwA-5hsoA:
undetectable
2riwB-5hsoA:
undetectable		 2riwA-5hsoA:
15.63
2riwB-5hsoA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 5hso UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887
(Mycobacterium
tuberculosis) 		5 / 10 ALA A  78
LEU A  28
LEU A  31
LEU A 102
LEU A  33
 None
 1.06A 2xn6A-5hsoA:
undetectable
2xn6B-5hsoA:
undetectable		 2xn6A-5hsoA:
15.56
2xn6B-5hsoA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5hso UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887
(Mycobacterium
tuberculosis) 		5 / 11 THR A  96
ALA A  78
GLY A  49
ALA A  93
SER A  45
 None
 1.19A 3mg0N-5hsoA:
undetectable		 3mg0N-5hsoA:
20.81