SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hsp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)
5hsp MAGNETOSOME PROTEIN
MAMM

(Magnetospirillum
gryphiswaldense)
5 / 9 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
None
0.92A 1hpvB-5hspA:
undetectable
1hpvB-5hspA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)
5hsp MAGNETOSOME PROTEIN
MAMM

(Magnetospirillum
gryphiswaldense)
4 / 5 ALA A 216
ALA A 239
ALA A 248
VAL A 274
None
0.91A 2nyrB-5hspA:
undetectable
2nyrB-5hspA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)
5hsp MAGNETOSOME PROTEIN
MAMM

(Magnetospirillum
gryphiswaldense)
5 / 9 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
None
1.03A 2q5kA-5hspA:
undetectable
2q5kA-5hspA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)
5hsp MAGNETOSOME PROTEIN
MAMM

(Magnetospirillum
gryphiswaldense)
5 / 11 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
None
0.98A 2qhcA-5hspA:
undetectable
2qhcA-5hspA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)
5hsp MAGNETOSOME PROTEIN
MAMM

(Magnetospirillum
gryphiswaldense)
5 / 9 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
None
1.04A 3ekvB-5hspA:
undetectable
3ekvB-5hspA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)
5hsp MAGNETOSOME PROTEIN
MAMM

(Magnetospirillum
gryphiswaldense)
5 / 10 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
None
1.00A 3nujA-5hspA:
undetectable
3nujA-5hspA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)
5hsp MAGNETOSOME PROTEIN
MAMM

(Magnetospirillum
gryphiswaldense)
5 / 10 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
None
0.99A 4dqcA-5hspA:
undetectable
4dqcA-5hspA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)
5hsp MAGNETOSOME PROTEIN
MAMM

(Magnetospirillum
gryphiswaldense)
5 / 10 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
None
0.93A 6dj2A-5hspA:
undetectable
6dj2A-5hspA:
19.38