SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ht7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WH5_A_3QBA204_1 (LINCOSAMIDE RESISTANCE PROTEIN)	5ht7	UNCHARACTERIZED PROTEIN (Methanothrix thermoacetophila)	5 / 12	ASP A 27 ASP A 21 ILE A 17 ALA A 2 HIS A 14	None None None None FE2 A 101 (-3.4A)	1.38A	4wh5A-5ht7A: undetectable	4wh5A-5ht7A: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_B_QDNB602_1 (CYTOCHROME P450 2D6)	5ht7	UNCHARACTERIZED PROTEIN (Methanothrix thermoacetophila)	5 / 9	GLU A 49 GLN A 53 PHE A 52 ALA A 22 ASP A 23	None	1.16A	4wnuB-5ht7A: undetectable	4wnuB-5ht7A: 9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_B_QDNB602_1 (CYTOCHROME P450 2D6)	5ht7	UNCHARACTERIZED PROTEIN (Methanothrix thermoacetophila)	5 / 9	GLU A 49 GLN A 53 PHE A 52 ALA A 22 SER A 78	None	1.38A	4wnuB-5ht7A: undetectable	4wnuB-5ht7A: 9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_D_QDND602_1 (CYTOCHROME P450 2D6)	5ht7	UNCHARACTERIZED PROTEIN (Methanothrix thermoacetophila)	5 / 10	GLU A 49 GLN A 53 PHE A 52 ALA A 22 ASP A 23	None	1.14A	4wnuD-5ht7A: undetectable	4wnuD-5ht7A: 9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_D_QDND602_1 (CYTOCHROME P450 2D6)	5ht7	UNCHARACTERIZED PROTEIN (Methanothrix thermoacetophila)	5 / 10	GLU A 49 GLN A 53 PHE A 52 ALA A 22 SER A 78	None	1.33A	4wnuD-5ht7A: undetectable	4wnuD-5ht7A: 9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FCT_B_C2FB402_0 (THYMIDYLATE SYNTHASE)	5ht7	UNCHARACTERIZED PROTEIN (Methanothrix thermoacetophila)	5 / 12	VAL A 39 PHE A 60 ILE A 68 LEU A 4 ALA A 32	None	1.49A	5fctB-5ht7A: undetectable	5fctB-5ht7A: 15.08

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4WH5_A_3QBA204_1","LINCOSAMIDE RESISTANCE PROTEIN","5ht7","UNCHARACTERIZED PROTEIN","Methanothrix thermoacetophila",5,"ASP A  27;ASP A  21;ILE A  17;ALA A   2;HIS A  14","None;None;None;None;FE2 A 101 (-3.4A)","1.38A","4wh5A-5ht7A:undetectable","4wh5A-5ht7A:19.25"],["4WNU_B_QDNB602_1","CYTOCHROME P450 2D6","5ht7","UNCHARACTERIZED PROTEIN","Methanothrix thermoacetophila",5,"GLU A  49;GLN A  53;PHE A  52;ALA A  22;ASP A  23","None","1.16A","4wnuB-5ht7A:undetectable","4wnuB-5ht7A:9.69"],["4WNU_B_QDNB602_1","CYTOCHROME P450 2D6","5ht7","UNCHARACTERIZED PROTEIN","Methanothrix thermoacetophila",5,"GLU A  49;GLN A  53;PHE A  52;ALA A  22;SER A  78","None","1.38A","4wnuB-5ht7A:undetectable","4wnuB-5ht7A:9.69"],["4WNU_D_QDND602_1","CYTOCHROME P450 2D6","5ht7","UNCHARACTERIZED PROTEIN","Methanothrix thermoacetophila",5,"GLU A  49;GLN A  53;PHE A  52;ALA A  22;ASP A  23","None","1.14A","4wnuD-5ht7A:undetectable","4wnuD-5ht7A:9.69"],["4WNU_D_QDND602_1","CYTOCHROME P450 2D6","5ht7","UNCHARACTERIZED PROTEIN","Methanothrix thermoacetophila",5,"GLU A  49;GLN A  53;PHE A  52;ALA A  22;SER A  78","None","1.33A","4wnuD-5ht7A:undetectable","4wnuD-5ht7A:9.69"],["5FCT_B_C2FB402_0","THYMIDYLATE SYNTHASE","5ht7","UNCHARACTERIZED PROTEIN","Methanothrix thermoacetophila",5,"VAL A  39;PHE A  60;ILE A  68;LEU A   4;ALA A  32","None","1.49A","5fctB-5ht7A:undetectable","5fctB-5ht7A:15.08"]]