SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5htf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UOF_A_PNNA1312_0 (DEACETOXYCEPHALOSPOR IN C SYNTHETASE)	5htf	FOLDASE PROTEIN PRSA 1 (Listeria monocytogenes)	5 / 11	PHE A 164 ASP A 193 THR A 195 SER A 210 VAL A 213	None MPD A 401 ( 4.3A) None None None	1.43A	1uofA-5htfA: undetectable	1uofA-5htfA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_A_C2FA3000_1 (DIHYDROPTEROATE SYNTHASE DHPS)	5htf	FOLDASE PROTEIN PRSA 1 (Listeria monocytogenes)	3 / 3	LYS A 270 ASN A 50 ASP A 268	None	0.90A	4o1eA-5htfA: undetectable	4o1eA-5htfA: 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_A_GCSA301_1 (CHITOSANASE)	5htf	FOLDASE PROTEIN PRSA 1 (Listeria monocytogenes)	3 / 3	TYR A 201 GLY A 188 PRO A 189	None	0.70A	4qwpA-5htfA: undetectable	4qwpA-5htfA: 22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YVN_A_ACTA305_0 (GLUTATHIONE S-TRANSFERASE OMEGA-1)	5htf	FOLDASE PROTEIN PRSA 1 (Listeria monocytogenes)	4 / 6	GLU A 107 GLN A 55 LYS A 59 LEU A 62	None	1.19A	5yvnA-5htfA: undetectable	5yvnA-5htfA: 22.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UOF_A_PNNA1312_0","DEACETOXYCEPHALOSPORIN C SYNTHETASE","5htf","FOLDASE PROTEIN PRSA 1","Listeria monocytogenes",5,"PHE A 164;ASP A 193;THR A 195;SER A 210;VAL A 213","None;MPD A 401 ( 4.3A);None;None;None","1.43A","1uofA-5htfA:undetectable","1uofA-5htfA:21.15"],["4O1E_A_C2FA3000_1","DIHYDROPTEROATE SYNTHASE DHPS","5htf","FOLDASE PROTEIN PRSA 1","Listeria monocytogenes",3,"LYS A 270;ASN A  50;ASP A 268","None","0.90A","4o1eA-5htfA:undetectable","4o1eA-5htfA:22.73"],["4QWP_A_GCSA301_1","CHITOSANASE","5htf","FOLDASE PROTEIN PRSA 1","Listeria monocytogenes",3,"TYR A 201;GLY A 188;PRO A 189","None","0.70A","4qwpA-5htfA:undetectable","4qwpA-5htfA:22.07"],["5YVN_A_ACTA305_0","GLUTATHIONE S-TRANSFERASE OMEGA-1","5htf","FOLDASE PROTEIN PRSA 1","Listeria monocytogenes",4,"GLU A 107;GLN A  55;LYS A  59;LEU A  62","None","1.19A","5yvnA-5htfA:undetectable","5yvnA-5htfA:22.70"]]