SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5huc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 ILE A 420
VAL A  84
GLY A  94
LEU A 116
 None
 0.86A 1dzmA-5hucA:
undetectable		 1dzmA-5hucA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 4 ILE A 315
LEU A 357
VAL A 360
ILE A 321
 None
 0.87A 1fm6D-5hucA:
undetectable		 1fm6D-5hucA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 THR A 105
ILE A 253
TYR A 141
ILE A 161
ALA A 182
 None
MPD  A 505 (-4.6A)
None
None
None
 1.25A 1jtxA-5hucA:
undetectable		 1jtxA-5hucA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 HIS A 257
ILE A 161
TYR A 264
ALA A  98
GLU A 265
 None
 1.32A 1ki7A-5hucA:
undetectable		 1ki7A-5hucA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 TYR A 157
GLY A 159
ALA A  98
ASP A 160
ILE A 161
 None
 1.18A 1nt2A-5hucA:
undetectable		 1nt2A-5hucA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 LEU A 454
GLY A 433
GLY A 432
ILE A 398
LEU A  92
 None
 1.14A 1p91A-5hucA:
undetectable		 1p91A-5hucA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 MET A 119
VAL A 122
LEU A 123
PHE A  90
 None
 1.15A 1x8vA-5hucA:
undetectable		 1x8vA-5hucA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 117
LEU A 207
GLY A 200
ASP A 203
ALA A 250
 TRP  A 506 ( 4.7A)
None
None
None
None
 1.09A 2br4A-5hucA:
undetectable		 2br4A-5hucA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ARG A 136
TRP A 290
PRO A 144
ALA A 142
 PEP  A 502 (-2.7A)
PEP  A 502 (-4.7A)
None
None
 1.45A 2ejgB-5hucA:
undetectable		 2ejgB-5hucA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 4 GLN A 362
GLU A 365
ILE A 361
PRO A 358
 None
 1.06A 2fcnA-5hucA:
undetectable		 2fcnA-5hucA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 GLN A 362
GLU A 365
ILE A 361
PRO A 358
 None
 0.89A 2fcnA-5hucA:
undetectable
2fcnB-5hucA:
undetectable		 2fcnA-5hucA:
9.93
2fcnB-5hucA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 TYR A 329
GLY A 297
VAL A 345
GLN A 374
GLY A 292
 None
None
None
None
PEP  A 502 (-3.2A)
 1.27A 3kmoA-5hucA:
undetectable		 3kmoA-5hucA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 400
LYS A 352
HIS A 350
ASN A 381
 None
 1.25A 3kp6A-5hucA:
undetectable
3kp6B-5hucA:
0.4		 3kp6A-5hucA:
16.09
3kp6B-5hucA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 GLU A 280
LEU A  75
LYS A  78
ALA A  71
 None
 1.05A 3mbgA-5hucA:
undetectable
3mbgB-5hucA:
undetectable		 3mbgA-5hucA:
16.96
3mbgB-5hucA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ALA A  89
ILE A 372
GLY A 417
ILE A 418
ILE A 132
 None
 1.06A 3ndwB-5hucA:
undetectable		 3ndwB-5hucA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A 361
THR A 343
GLY A 417
ILE A 344
VAL A 345
 None
 1.04A 4c9lA-5hucA:
undetectable		 4c9lA-5hucA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A 361
THR A 343
GLY A 417
ILE A 344
VAL A 345
 None
 1.06A 4c9lB-5hucA:
undetectable		 4c9lB-5hucA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A 361
THR A 343
GLY A 417
ILE A 344
VAL A 345
 None
 0.99A 4c9oA-5hucA:
undetectable		 4c9oA-5hucA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A 361
THR A 343
GLY A 417
ILE A 344
VAL A 345
 None
 1.01A 4c9oB-5hucA:
undetectable		 4c9oB-5hucA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 285
TYR A 264
GLN A 140
ALA A 142
GLY A 292
 None
None
None
None
PEP  A 502 (-3.2A)
 0.95A 4j7xA-5hucA:
undetectable		 4j7xA-5hucA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 285
TYR A 264
GLN A 140
ALA A 142
GLY A 292
 None
None
None
None
PEP  A 502 (-3.2A)
 0.97A 4j7xB-5hucA:
undetectable		 4j7xB-5hucA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A 317
ILE A 132
LEU A  77
GLY A 340
ILE A 372
 None
 0.91A 4o1eB-5hucA:
3.6		 4o1eB-5hucA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 376
HIS A 419
ARG A 136
ARG A 392
 PEP  A 502 ( 4.8A)
None
PEP  A 502 (-2.7A)
MN  A 501 ( 4.3A)
 1.49A 4qyqC-5hucA:
undetectable		 4qyqC-5hucA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 421
ASP A  96
SER A 448
PRO A 452
 MN  A 501 (-2.0A)
None
None
None
 0.81A 4uhxA-5hucA:
undetectable		 4uhxA-5hucA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 GLU A 421
ASP A  96
SER A 448
PRO A 452
 MN  A 501 (-2.0A)
None
None
None
 0.81A 4uhxA-5hucA:
undetectable		 4uhxA-5hucA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 LEU A 123
LEU A 465
VAL A 466
PHE A 464
 None
 1.23A 4uswA-5hucA:
undetectable		 4uswA-5hucA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 PHE A  90
PRO A 130
VAL A 131
ALA A 127
 None
 1.11A 4w5oA-5hucA:
undetectable		 4w5oA-5hucA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 PHE A  90
PRO A 130
VAL A 131
ALA A 127
 None
 1.10A 4z4cA-5hucA:
undetectable		 4z4cA-5hucA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 PHE A  90
PRO A 130
VAL A 131
ALA A 127
 None
 1.14A 4z4dA-5hucA:
undetectable		 4z4dA-5hucA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 PHE A  90
PRO A 130
VAL A 131
ALA A 127
 None
 1.12A 4z4eA-5hucA:
undetectable		 4z4eA-5hucA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 GLY A 340
VAL A 364
LEU A 411
GLU A 365
THR A 413
 None
 1.17A 4zmeA-5hucA:
undetectable		 4zmeA-5hucA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 376
HIS A 419
ARG A 136
ARG A 392
 PEP  A 502 ( 4.8A)
None
PEP  A 502 (-2.7A)
MN  A 501 ( 4.3A)
 1.49A 5hpwC-5hucA:
undetectable		 5hpwC-5hucA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		3 / 3 VAL A  69
GLN A 288
CYH A 255
 None
 0.82A 5icxA-5hucA:
undetectable
5icxE-5hucA:
undetectable		 5icxA-5hucA:
17.90
5icxE-5hucA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		3 / 3 VAL A  69
GLN A 288
CYH A 255
 None
 0.88A 5icxC-5hucA:
undetectable
5icxF-5hucA:
undetectable		 5icxC-5hucA:
17.90
5icxF-5hucA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 263
ASP A 160
ARG A 181
ASN A 185
 None
None
MPD  A 504 ( 4.9A)
MPD  A 504 (-3.4A)
 1.01A 5l6eA-5hucA:
undetectable		 5l6eA-5hucA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 PHE A  90
PRO A 130
VAL A 131
ALA A 127
 None
 1.06A 5t7bA-5hucA:
undetectable		 5t7bA-5hucA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 PHE A 422
GLY A  94
GLY A  95
ILE A 137
LEU A 196
 None
 1.10A 5ul4A-5hucA:
2.5		 5ul4A-5hucA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 PHE A 422
GLY A  94
GLY A  95
ILE A 137
MET A 190
 None
 1.17A 5ul4A-5hucA:
2.5		 5ul4A-5hucA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		3 / 3 ARG A 145
LYS A 143
ARG A 181
 None
PEP  A 502 ( 3.8A)
MPD  A 504 ( 4.9A)
 1.24A 6c06D-5hucA:
undetectable		 6c06D-5hucA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 GLN A 457
ASN A 455
ILE A 437
GLU A 435
 None
 0.93A 6hzpA-5hucA:
undetectable		 6hzpA-5hucA:
19.88