SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5huj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2001_1 (SERUM ALBUMIN)	5huj	NH(3)-DEPENDENT NAD(+) SYNTHETASE (Streptococcus pyogenes)	5 / 12	ILE A 15 PHE A 193 VAL A 21 GLY A 20 LEU A 246	None	1.14A	2bxeB-5hujA: undetectable	2bxeB-5hujA: 20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E00_A_9CRA7223_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	5huj	NH(3)-DEPENDENT NAD(+) SYNTHETASE (Streptococcus pyogenes)	5 / 12	ALA A 110 PHE A 108 ALA A 107 VAL A 35 ILE A 31	None	1.06A	3e00A-5hujA: undetectable	3e00A-5hujA: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3006_1 (TRANSCRIPTIONAL REGULATOR TCAR)	5huj	NH(3)-DEPENDENT NAD(+) SYNTHETASE (Streptococcus pyogenes)	4 / 6	ASN A 196 ILE A 25 GLU A 247 LYS A 22	None	1.31A	3kp6A-5hujA: undetectable 3kp6B-5hujA: undetectable	3kp6A-5hujA: 20.07 3kp6B-5hujA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TIX_B_OQRB302_0 (SULFOTRANSFERASE)	5huj	NH(3)-DEPENDENT NAD(+) SYNTHETASE (Streptococcus pyogenes)	5 / 10	ILE A 189 LEU A 67 LEU A 195 PHE A 37 GLU A 30	None	1.28A	5tixB-5hujA: undetectable	5tixB-5hujA: 20.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BXE_B_1FLB2001_1","SERUM ALBUMIN","5huj","NH(3)-DEPENDENT NAD(+) SYNTHETASE","Streptococcus pyogenes",5,"ILE A  15;PHE A 193;VAL A  21;GLY A  20;LEU A 246","None","1.14A","2bxeB-5hujA:undetectable","2bxeB-5hujA:20.41"],["3E00_A_9CRA7223_1","RETINOIC ACID RECEPTOR RXR-ALPHA","5huj","NH(3)-DEPENDENT NAD(+) SYNTHETASE","Streptococcus pyogenes",5,"ALA A 110;PHE A 108;ALA A 107;VAL A  35;ILE A  31","None","1.06A","3e00A-5hujA:undetectable","3e00A-5hujA:21.14"],["3KP6_B_SALB3006_1","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","5huj","NH(3)-DEPENDENT NAD(+) SYNTHETASE","Streptococcus pyogenes",4,"ASN A 196;ILE A  25;GLU A 247;LYS A  22","None","1.31A","3kp6A-5hujA:undetectable;3kp6B-5hujA:undetectable","3kp6A-5hujA:20.07;3kp6B-5hujA:20.07"],["5TIX_B_OQRB302_0","SULFOTRANSFERASE","5huj","NH(3)-DEPENDENT NAD(+) SYNTHETASE","Streptococcus pyogenes",5,"ILE A 189;LEU A  67;LEU A 195;PHE A  37;GLU A  30","None","1.28A","5tixB-5hujA:undetectable","5tixB-5hujA:20.59"]]