SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5huu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 4 THR A 434
LEU A 433
LEU A 310
GLN A 312
 None
 1.13A 1fbmA-5huuA:
undetectable		 1fbmA-5huuA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 8 PHE A 240
GLY A 460
LEU A  41
PHE A 169
 None
 0.86A 1gsfA-5huuA:
1.9		 1gsfA-5huuA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 8 PHE A 240
GLY A 460
LEU A  41
PHE A 169
 None
 0.86A 1gsfB-5huuA:
1.9		 1gsfB-5huuA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 8 PHE A 240
GLY A 460
LEU A  41
PHE A 169
 None
 0.86A 1gsfC-5huuA:
undetectable		 1gsfC-5huuA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 8 PHE A 240
GLY A 460
LEU A  41
PHE A 169
 None
 0.86A 1gsfD-5huuA:
1.9		 1gsfD-5huuA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 11 ARG A 280
HIS A 354
SER A 317
LEU A 281
LEU A 327
 UDP  A 501 (-3.8A)
None
G6P  A 502 ( 4.3A)
None
None
 1.41A 1hwkB-5huuA:
undetectable		 1hwkB-5huuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 11 ARG A 280
HIS A 354
SER A 317
LEU A 281
LEU A 327
 UDP  A 501 (-3.8A)
None
G6P  A 502 ( 4.3A)
None
None
 1.41A 1hwkA-5huuA:
undetectable		 1hwkA-5huuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_2
(HMG-COA REDUCTASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 11 ARG A 280
HIS A 354
SER A 317
LEU A 281
LEU A 327
 UDP  A 501 (-3.8A)
None
G6P  A 502 ( 4.3A)
None
None
 1.40A 1hwkD-5huuA:
undetectable		 1hwkD-5huuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 11 ARG A 280
HIS A 354
SER A 317
LEU A 281
LEU A 327
 UDP  A 501 (-3.8A)
None
G6P  A 502 ( 4.3A)
None
None
 1.41A 1hwkC-5huuA:
undetectable		 1hwkC-5huuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 TYR A 386
HIS A 142
GLY A 200
TRP A 140
 None
 1.33A 1mxgA-5huuA:
undetectable		 1mxgA-5huuA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 10 TYR A 180
PHE A  92
LEU A  97
MET A 147
GLY A 192
 None
 1.33A 1uhoA-5huuA:
undetectable		 1uhoA-5huuA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 SER A 375
TYR A 283
SER A 332
ASP A 279
 None
 1.30A 1vidA-5huuA:
3.1		 1vidA-5huuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 TRP A 420
ARG A 378
PHE A 404
 None
 1.44A 1zeaH-5huuA:
undetectable
1zeaL-5huuA:
undetectable		 1zeaH-5huuA:
16.91
1zeaL-5huuA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 0.96A 2eikC-5huuA:
undetectable
2eikJ-5huuA:
undetectable		 2eikC-5huuA:
19.58
2eikJ-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 ILE A 217
PHE A 174
PHE A 210
ILE A 189
 None
 1.13A 2hjhA-5huuA:
2.1		 2hjhA-5huuA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 10 SER A 385
ALA A 407
ASN A 382
ALA A 405
ALA A 408
 None
None
UDP  A 501 ( 4.0A)
None
None
 1.14A 2r2vC-5huuA:
undetectable
2r2vF-5huuA:
undetectable
2r2vG-5huuA:
undetectable		 2r2vC-5huuA:
5.24
2r2vF-5huuA:
5.24
2r2vG-5huuA:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 ARG A 318
GLY A 319
SER A 332
 G6P  A 502 (-3.7A)
None
None
 0.50A 2xctB-5huuA:
undetectable		 2xctB-5huuA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.00A 3abkP-5huuA:
undetectable
3abkW-5huuA:
undetectable		 3abkP-5huuA:
19.58
3abkW-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.06A 3ablP-5huuA:
undetectable
3ablW-5huuA:
undetectable		 3ablP-5huuA:
19.58
3ablW-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 110
PHE A  92
LEU A  97
PHE A 101
 None
 1.39A 3abmP-5huuA:
undetectable
3abmW-5huuA:
undetectable		 3abmP-5huuA:
19.58
3abmW-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 110
PHE A  92
LEU A  97
PHE A 101
 None
 1.31A 3ag3C-5huuA:
undetectable
3ag3J-5huuA:
undetectable		 3ag3C-5huuA:
19.58
3ag3J-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.05A 3ag3C-5huuA:
undetectable
3ag3J-5huuA:
undetectable		 3ag3C-5huuA:
19.58
3ag3J-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 ASP A 279
LEU A 373
LEU A 334
HIS A 292
 None
 1.11A 3bj8C-5huuA:
undetectable
3bj8D-5huuA:
undetectable		 3bj8C-5huuA:
17.93
3bj8D-5huuA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 TRP A 115
PHE A  92
GLU A 112
VAL A 185
 None
 1.15A 3dqrA-5huuA:
undetectable
3dqrB-5huuA:
undetectable		 3dqrA-5huuA:
22.55
3dqrB-5huuA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 12 PHE A 169
LEU A 383
MET A 381
GLY A 243
ALA A  37
 None
UDP  A 501 (-4.0A)
None
None
None
 1.31A 3lbdA-5huuA:
undetectable		 3lbdA-5huuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 VAL A 185
PHE A  92
LEU A 148
ILE A 119
 None
 1.02A 3rfmA-5huuA:
undetectable		 3rfmA-5huuA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 0.93A 3wg7C-5huuA:
undetectable
3wg7J-5huuA:
undetectable		 3wg7C-5huuA:
19.58
3wg7J-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 VAL A   9
LEU A 146
LEU A 149
ILE A  78
 None
 0.85A 4a9jA-5huuA:
undetectable		 4a9jA-5huuA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 VAL A   9
LEU A 146
LEU A 149
ILE A  78
 None
 0.90A 4a9jB-5huuA:
undetectable		 4a9jB-5huuA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 VAL A   9
LEU A 146
LEU A 149
ILE A  78
 None
 0.86A 4a9jC-5huuA:
undetectable		 4a9jC-5huuA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 8 ILE A 157
ILE A 129
LEU A   7
ILE A 139
 None
 0.89A 4dtaB-5huuA:
undetectable		 4dtaB-5huuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 SER A  93
TYR A 118
PRO A  99
 None
 0.68A 4k8cA-5huuA:
4.8		 4k8cA-5huuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 SER A  93
TYR A 118
PRO A  99
 None
 0.66A 4kahA-5huuA:
5.1		 4kahA-5huuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 SER A  93
TYR A 118
PRO A  99
 None
 0.66A 4kahB-5huuA:
3.7		 4kahB-5huuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 SER A  93
TYR A 118
PRO A  99
 None
 0.69A 4kanA-5huuA:
4.8		 4kanA-5huuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 SER A  93
TYR A 118
PRO A  99
 None
 0.67A 4kanB-5huuA:
3.7		 4kanB-5huuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 SER A  93
TYR A 118
PRO A  99
 None
 0.65A 4kbeA-5huuA:
5.4		 4kbeA-5huuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 SER A  93
TYR A 118
PRO A  99
 None
 0.66A 4kbeB-5huuA:
5.1		 4kbeB-5huuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 12 ILE A  57
GLY A  54
ILE A  78
ALA A  77
ALA A 121
 None
 1.03A 4kicB-5huuA:
undetectable		 4kicB-5huuA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 SER A  93
TYR A 118
PRO A  99
 None
 0.67A 4lbgA-5huuA:
3.6		 4lbgA-5huuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		3 / 3 SER A  93
TYR A 118
PRO A  99
 None
 0.67A 4lbgB-5huuA:
4.4		 4lbgB-5huuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 GLY A  51
ILE A 129
LYS A 131
GLN A 132
 None
 0.98A 4ma8C-5huuA:
undetectable		 4ma8C-5huuA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 12 LEU A 298
PHE A 294
ILE A 305
ILE A 275
VAL A 272
 None
 0.87A 4nkxC-5huuA:
undetectable		 4nkxC-5huuA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 TYR A 180
ILE A 199
LEU A 170
PHE A 168
 None
 1.14A 4uymB-5huuA:
undetectable		 4uymB-5huuA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 PRO A 175
PHE A 101
TRP A  98
TYR A 283
 None
 1.41A 4v2yA-5huuA:
undetectable		 4v2yA-5huuA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 PRO A 175
PHE A 101
TRP A  98
TYR A 283
 None
 1.44A 4v30A-5huuA:
undetectable		 4v30A-5huuA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 PRO A 175
PHE A 101
TRP A  98
TYR A 283
 None
 1.44A 5amhA-5huuA:
undetectable		 5amhA-5huuA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 PRO A 175
PHE A 101
TRP A  98
TYR A 283
 None
 1.44A 5amkB-5huuA:
undetectable		 5amkB-5huuA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.06A 5b1bC-5huuA:
undetectable
5b1bJ-5huuA:
undetectable		 5b1bC-5huuA:
19.58
5b1bJ-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 0.95A 5b1bP-5huuA:
undetectable
5b1bW-5huuA:
undetectable		 5b1bP-5huuA:
19.58
5b1bW-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 12 GLY A 406
GLN A 409
PHE A 463
ILE A 139
GLY A 167
 None
 1.10A 5fsaB-5huuA:
undetectable		 5fsaB-5huuA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 269
PHE A 444
VAL A 276
ASP A 370
 None
 1.25A 5hesA-5huuA:
undetectable		 5hesA-5huuA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 12 LEU A  97
TRP A 115
VAL A 193
GLY A 192
TYR A 118
 None
 1.21A 5nnaA-5huuA:
undetectable		 5nnaA-5huuA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 12 LEU A  97
TRP A 115
VAL A 193
GLY A 192
TYR A 118
 None
 1.20A 5nnaD-5huuA:
undetectable		 5nnaD-5huuA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 PRO A 175
PHE A 101
TRP A  98
TYR A 283
 None
 1.39A 5oh1A-5huuA:
undetectable		 5oh1A-5huuA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 7 PRO A 175
PHE A 101
TRP A  98
TYR A 283
 None
 1.44A 5oh1B-5huuA:
undetectable		 5oh1B-5huuA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 110
PHE A  92
LEU A  97
PHE A 101
 None
 1.33A 5wauC-5huuA:
undetectable
5wauJ-5huuA:
undetectable		 5wauC-5huuA:
19.58
5wauJ-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.02A 5wauC-5huuA:
undetectable
5wauJ-5huuA:
undetectable		 5wauC-5huuA:
19.58
5wauJ-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 110
PHE A  92
LEU A  97
PHE A 101
 None
 1.32A 5wauc-5huuA:
undetectable
5wauj-5huuA:
undetectable		 5wauc-5huuA:
19.58
5wauj-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 0.98A 5wauc-5huuA:
undetectable
5wauj-5huuA:
undetectable		 5wauc-5huuA:
19.58
5wauj-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 110
PHE A  92
LEU A  97
PHE A 101
 None
 1.34A 5xdqC-5huuA:
undetectable
5xdqJ-5huuA:
undetectable		 5xdqC-5huuA:
19.58
5xdqJ-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.03A 5xdqC-5huuA:
undetectable
5xdqJ-5huuA:
undetectable		 5xdqC-5huuA:
19.58
5xdqJ-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 110
PHE A  92
LEU A  97
PHE A 101
 None
 1.32A 5xdqP-5huuA:
undetectable
5xdqW-5huuA:
undetectable		 5xdqP-5huuA:
19.58
5xdqW-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.00A 5xdqP-5huuA:
undetectable
5xdqW-5huuA:
undetectable		 5xdqP-5huuA:
19.58
5xdqW-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 0.98A 5z84P-5huuA:
undetectable
5z84W-5huuA:
undetectable		 5z84P-5huuA:
19.58
5z84W-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 0.96A 5z85P-5huuA:
undetectable
5z85W-5huuA:
undetectable		 5z85P-5huuA:
19.58
5z85W-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.00A 5z86C-5huuA:
undetectable
5z86J-5huuA:
undetectable		 5z86C-5huuA:
19.58
5z86J-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 0.99A 5z86P-5huuA:
undetectable
5z86W-5huuA:
undetectable		 5z86P-5huuA:
19.58
5z86W-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.00A 5zcoP-5huuA:
undetectable
5zcoW-5huuA:
undetectable		 5zcoP-5huuA:
19.58
5zcoW-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 0.99A 5zcpC-5huuA:
undetectable
5zcpJ-5huuA:
undetectable		 5zcpC-5huuA:
19.58
5zcpJ-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 6 PHE A 174
PHE A 101
LEU A  97
PHE A  92
 None
 1.02A 5zcpP-5huuA:
undetectable
5zcpW-5huuA:
undetectable		 5zcpP-5huuA:
19.58
5zcpW-5huuA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 THR A 330
THR A 377
GLN A 289
ASP A 379
 None
None
None
UDP  A 501 ( 4.9A)
 1.16A 6ectA-5huuA:
undetectable		 6ectA-5huuA:
20.80