SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hva'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 5hva DR2231
(Deinococcus
radiodurans) 		5 / 12 LEU A  39
GLY A  89
ALA A  90
GLY A  95
PRO A  33
 None
 0.88A 2hs1B-5hvaA:
undetectable		 2hs1B-5hvaA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 5hva DR2231
(Deinococcus
radiodurans) 		4 / 7 LEU A  83
VAL A  86
THR A  87
ASP A  45
 None
 0.86A 2qblA-5hvaA:
undetectable		 2qblA-5hvaA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 5hva DR2231
(Deinococcus
radiodurans) 		3 / 3 GLU A  47
HIS A  78
GLU A  79
 MG  A 201 (-2.7A)
None
MG  A 201 (-2.6A)
 0.65A 2x45B-5hvaA:
undetectable		 2x45B-5hvaA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 5hva DR2231
(Deinococcus
radiodurans) 		3 / 3 GLU A  47
HIS A  78
GLU A  79
 MG  A 201 (-2.7A)
None
MG  A 201 (-2.6A)
 0.64A 2x45C-5hvaA:
undetectable		 2x45C-5hvaA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 5hva DR2231
(Deinococcus
radiodurans) 		5 / 12 LEU A  39
GLY A  89
ALA A  90
GLY A  95
PRO A  33
 None
 0.94A 3pwrA-5hvaA:
undetectable		 3pwrA-5hvaA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 5hva DR2231
(Deinococcus
radiodurans) 		4 / 5 GLY A  95
PRO A  33
THR A  30
THR A  25
 None
 1.24A 5h5fA-5hvaA:
undetectable		 5h5fA-5hvaA:
23.75