SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hvm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 7 PHE A  87
GLY A  62
ILE A  23
GLY A  59
 None
 0.70A 11gsB-5hvmA:
undetectable		 11gsB-5hvmA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 11 ARG A 287
HIS A 361
SER A 324
LEU A 288
LEU A 334
 VDM  A 602 (-3.2A)
None
VDM  A 602 ( 4.2A)
None
None
 1.36A 1hwkB-5hvmA:
undetectable		 1hwkB-5hvmA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 TRP A 123
HIS A  96
TYR A 126
GLY A  99
 None
 1.50A 1mxdA-5hvmA:
2.2		 1mxdA-5hvmA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 7 TYR A 393
HIS A 150
GLY A 208
TRP A 148
 None
 1.32A 1mxgA-5hvmA:
2.3		 1mxgA-5hvmA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 TRP A 427
ARG A 385
PHE A 411
 None
 1.47A 1zeaH-5hvmA:
undetectable
1zeaL-5hvmA:
undetectable		 1zeaH-5hvmA:
17.81
1zeaL-5hvmA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 GLN A 238
HIS A 203
ARG A 162
 None
 0.93A 1zlqA-5hvmA:
0.0		 1zlqA-5hvmA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 12 TYR A 373
ILE A 380
VAL A 381
ALA A 321
VAL A 391
 None
None
None
None
UDP  A 601 (-4.0A)
 1.06A 2g72B-5hvmA:
undetectable		 2g72B-5hvmA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 118
PHE A 100
LEU A 105
PHE A 109
 None
 1.31A 2y69C-5hvmA:
undetectable
2y69J-5hvmA:
undetectable		 2y69C-5hvmA:
18.38
2y69J-5hvmA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 118
PHE A 100
LEU A 105
PHE A 109
 None
 1.34A 2y69P-5hvmA:
undetectable
2y69W-5hvmA:
undetectable		 2y69P-5hvmA:
18.38
2y69W-5hvmA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 12 LEU A 154
GLY A 175
PRO A 158
LEU A  16
PHE A  55
 None
 1.15A 2zzmA-5hvmA:
2.3		 2zzmA-5hvmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 1.03A 3ablP-5hvmA:
undetectable
3ablW-5hvmA:
undetectable		 3ablP-5hvmA:
18.38
3ablW-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 118
PHE A 100
LEU A 105
PHE A 109
 None
 1.32A 3abmC-5hvmA:
undetectable
3abmJ-5hvmA:
undetectable		 3abmC-5hvmA:
18.38
3abmJ-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 118
PHE A 100
LEU A 105
PHE A 109
 None
 1.30A 3abmP-5hvmA:
undetectable
3abmW-5hvmA:
undetectable		 3abmP-5hvmA:
18.38
3abmW-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 118
PHE A 100
LEU A 105
PHE A 109
 None
 1.23A 3ag3C-5hvmA:
undetectable
3ag3J-5hvmA:
undetectable		 3ag3C-5hvmA:
18.38
3ag3J-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.99A 3ag3C-5hvmA:
undetectable
3ag3J-5hvmA:
undetectable		 3ag3C-5hvmA:
18.38
3ag3J-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 12 TYR A 373
ALA A 392
SER A 421
ALA A 378
ILE A 380
 None
 1.15A 3id6C-5hvmA:
2.5		 3id6C-5hvmA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 9 ILE A 251
LEU A 454
PHE A 451
LEU A 372
GLY A 404
 None
 1.36A 3nxuB-5hvmA:
undetectable		 3nxuB-5hvmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 LEU A  14
TRP A  57
LEU A 474
ASP A 145
 None
 1.23A 4aqlA-5hvmA:
undetectable		 4aqlA-5hvmA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 SER A 101
TYR A 126
PRO A 107
 None
 0.67A 4k8cA-5hvmA:
3.0		 4k8cA-5hvmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 SER A 101
TYR A 126
PRO A 107
 None
 0.66A 4kahA-5hvmA:
3.1		 4kahA-5hvmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 SER A 101
TYR A 126
PRO A 107
 None
 0.65A 4kahB-5hvmA:
3.3		 4kahB-5hvmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 SER A 101
TYR A 126
PRO A 107
 None
 0.67A 4kanA-5hvmA:
3.6		 4kanA-5hvmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 SER A 101
TYR A 126
PRO A 107
 None
 0.66A 4kanB-5hvmA:
2.9		 4kanB-5hvmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 SER A 101
TYR A 126
PRO A 107
 None
 0.66A 4kbeA-5hvmA:
3.0		 4kbeA-5hvmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 SER A 101
TYR A 126
PRO A 107
 None
 0.67A 4kbeB-5hvmA:
3.0		 4kbeB-5hvmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 SER A 101
TYR A 126
PRO A 107
 None
 0.65A 4lbgA-5hvmA:
2.9		 4lbgA-5hvmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		3 / 3 SER A 101
TYR A 126
PRO A 107
 None
 0.65A 4lbgB-5hvmA:
3.6		 4lbgB-5hvmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 10 HIS A  96
TYR A  97
ALA A 136
ALA A 129
GLY A  59
 None
 1.26A 4rn6A-5hvmA:
undetectable		 4rn6A-5hvmA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 7 PRO A 183
PHE A 109
TRP A 106
TYR A 290
 None
 1.47A 4v2yA-5hvmA:
undetectable		 4v2yA-5hvmA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 ILE A  84
GLN A  56
ILE A 147
ASP A 145
 None
 1.15A 4w5qA-5hvmA:
2.3		 4w5qA-5hvmA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 7 PHE A 304
LEU A 301
THR A 441
VAL A 315
 None
 0.89A 4wnvD-5hvmA:
undetectable		 4wnvD-5hvmA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 ILE A  84
GLN A  56
ILE A 147
ASP A 145
 None
 1.20A 4z4dA-5hvmA:
undetectable		 4z4dA-5hvmA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 7 PRO A 183
PHE A 109
TRP A 106
TYR A 290
 None
 1.49A 5amkB-5hvmA:
undetectable		 5amkB-5hvmA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 1.03A 5b1bC-5hvmA:
undetectable
5b1bJ-5hvmA:
undetectable		 5b1bC-5hvmA:
18.38
5b1bJ-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 7 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.90A 5b1bP-5hvmA:
undetectable
5b1bW-5hvmA:
undetectable		 5b1bP-5hvmA:
18.38
5b1bW-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 9 ARG A 131
ALA A 134
LEU A 156
LEU A 157
LEU A 161
 None
 1.16A 5dqfA-5hvmA:
undetectable		 5dqfA-5hvmA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 4 VAL A  43
ALA A 464
ILE A 251
THR A 462
 None
 1.10A 5e4dB-5hvmA:
undetectable		 5e4dB-5hvmA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 12 GLY A 413
GLN A 416
PHE A 470
ILE A 147
GLY A 175
 None
 1.10A 5fsaB-5hvmA:
undetectable		 5fsaB-5hvmA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 12 GLY A 420
PHE A 451
GLN A 399
TYR A 393
ALA A 414
 None
 1.23A 5n0xB-5hvmA:
undetectable		 5n0xB-5hvmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 7 PRO A 183
PHE A 109
TRP A 106
TYR A 290
 None
 1.46A 5oh1A-5hvmA:
undetectable		 5oh1A-5hvmA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 8 GLN A 142
GLY A 144
ILE A 165
ASP A 205
 None
 1.00A 5vlmH-5hvmA:
undetectable		 5vlmH-5hvmA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 118
PHE A 100
LEU A 105
PHE A 109
 None
 1.24A 5wauC-5hvmA:
undetectable
5wauJ-5hvmA:
undetectable		 5wauC-5hvmA:
18.38
5wauJ-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 118
PHE A 100
LEU A 105
PHE A 109
 None
 1.23A 5wauc-5hvmA:
undetectable
5wauj-5hvmA:
undetectable		 5wauc-5hvmA:
18.38
5wauj-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.93A 5wauc-5hvmA:
undetectable
5wauj-5hvmA:
undetectable		 5wauc-5hvmA:
18.38
5wauj-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 118
PHE A 100
LEU A 105
PHE A 109
 None
 1.26A 5xdqC-5hvmA:
undetectable
5xdqJ-5hvmA:
undetectable		 5xdqC-5hvmA:
18.38
5xdqJ-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 118
PHE A 100
LEU A 105
PHE A 109
 None
 1.24A 5xdqP-5hvmA:
undetectable
5xdqW-5hvmA:
undetectable		 5xdqP-5hvmA:
18.38
5xdqW-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 5 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.94A 5xdqP-5hvmA:
undetectable
5xdqW-5hvmA:
undetectable		 5xdqP-5hvmA:
18.38
5xdqW-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 12 PHE A 218
LEU A 191
ILE A 187
LEU A 202
LEU A 226
 None
 1.22A 5ycpA-5hvmA:
undetectable		 5ycpA-5hvmA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.92A 5z84P-5hvmA:
undetectable
5z84W-5hvmA:
undetectable		 5z84P-5hvmA:
18.38
5z84W-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.90A 5z85P-5hvmA:
undetectable
5z85W-5hvmA:
undetectable		 5z85P-5hvmA:
18.38
5z85W-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.93A 5z86C-5hvmA:
undetectable
5z86J-5hvmA:
undetectable		 5z86C-5hvmA:
18.38
5z86J-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.92A 5z86P-5hvmA:
undetectable
5z86W-5hvmA:
undetectable		 5z86P-5hvmA:
18.38
5z86W-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.94A 5zcoP-5hvmA:
undetectable
5zcoW-5hvmA:
undetectable		 5zcoP-5hvmA:
18.38
5zcoW-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.93A 5zcpC-5hvmA:
undetectable
5zcpJ-5hvmA:
undetectable		 5zcpC-5hvmA:
18.38
5zcpJ-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 6 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.95A 5zcpP-5hvmA:
undetectable
5zcpW-5hvmA:
undetectable		 5zcpP-5hvmA:
18.38
5zcpW-5hvmA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 7 PHE A 182
PHE A 109
LEU A 105
PHE A 100
 None
 0.90A 5zcqP-5hvmA:
undetectable
5zcqW-5hvmA:
undetectable		 5zcqP-5hvmA:
18.38
5zcqW-5hvmA:
8.18