SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hwq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4L_B_DCFB853_2 (ADENOSINE DEAMINASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 5	HIS A 250 SER A 144 LEU A 56 GLY A 160	CSO A 115 (-3.5A) None None None	1.13A	1a4lB-5hwqA: undetectable	1a4lB-5hwqA: 22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT2_A_SAMA301_0 (FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	ALA A 163 SER A 144 THR A 59 SER A 314 ALA A 320	None	1.02A	1nt2A-5hwqA: undetectable	1nt2A-5hwqA: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SKX_A_RFPA1_2 (ORPHAN NUCLEAR RECEPTOR PXR)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 5	LYS A 259 PHE A 348 LEU A 213 LEU A 322	CAA A 501 (-2.7A) None None None	1.21A	1skxA-5hwqA: undetectable	1skxA-5hwqA: 21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VPO_H_TESH1010_1 (ANTI-TESTOSTERONE (HEAVY CHAIN) ANTI-TESTOSTERONE (LIGHT CHAIN))	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	TYR A 349 ALA A 318 TYR A 316 GLY A 321 LEU A 322	None	1.23A	1vpoH-5hwqA: undetectable 1vpoL-5hwqA: undetectable	1vpoH-5hwqA: 20.00 1vpoL-5hwqA: 17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AA6_A_STRA401_1 (MINERALOCORTICOID RECEPTOR)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	LEU A 303 LEU A 317 ALA A 318 LEU A 10 MET A 361	None	1.44A	2aa6A-5hwqA: undetectable	2aa6A-5hwqA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DU8_B_BEZB1352_0 (D-AMINO-ACID OXIDASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 6	LEU A 122 TYR A 349 ILE A 7 GLY A 336	None	0.91A	2du8B-5hwqA: undetectable	2du8B-5hwqA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IEO_A_017A402_2 (PROTEASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	GLY A 321 ALA A 320 VAL A 164 VAL A 14 VAL A 12	None	0.82A	2ieoB-5hwqA: undetectable	2ieoB-5hwqA: 12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QL8_A_BEZA143_0 (PUTATIVE REDOX PROTEIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 7	ALA A 58 THR A 59 ALA A 62 ARG A 66	None	0.90A	2ql8A-5hwqA: 1.0 2ql8B-5hwqA: undetectable	2ql8A-5hwqA: 18.02 2ql8B-5hwqA: 18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VH3_A_DAHA2_1 (RANASMURFIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 9	ALA A 11 ALA A 13 PHE A 402 GLY A 400 ALA A 62	None	1.24A	2vh3A-5hwqA: undetectable	2vh3A-5hwqA: 12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y6R_A_CTCA1385_0 (TETX2 PROTEIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	MET A 256 PHE A 253 ASN A 304 GLY A 40 PRO A 157	CAA A 501 ( 3.7A) CAA A 501 (-3.6A) None GOL A 502 (-3.0A) CAA A 501 ( 4.6A)	1.40A	2y6rA-5hwqA: undetectable	2y6rA-5hwqA: 23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BWC_A_SAMA501_0 (SPERMIDINE SYNTHASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	ILE A 335 GLY A 336 ASP A 178 GLY A 351 GLN A 296	None	1.05A	3bwcA-5hwqA: undetectable	3bwcA-5hwqA: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E00_A_9CRA7223_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	ALA A 163 ALA A 57 ARG A 63 ALA A 13 ILE A 75	None	1.09A	3e00A-5hwqA: undetectable	3e00A-5hwqA: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6G_B_TA1B502_1 (TUBULIN BETA CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.49A	3j6gB-5hwqA: undetectable	3j6gB-5hwqA: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6G_D_TA1D502_1 (TUBULIN BETA CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.49A	3j6gD-5hwqA: undetectable	3j6gD-5hwqA: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6G_F_TA1F502_1 (TUBULIN BETA CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.49A	3j6gF-5hwqA: undetectable	3j6gF-5hwqA: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6G_H_TA1H502_1 (TUBULIN BETA CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.49A	3j6gH-5hwqA: undetectable	3j6gH-5hwqA: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6G_J_TA1J502_1 (TUBULIN BETA CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.49A	3j6gJ-5hwqA: undetectable	3j6gJ-5hwqA: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6G_L_TA1L502_1 (TUBULIN BETA CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.49A	3j6gL-5hwqA: undetectable	3j6gL-5hwqA: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6G_N_TA1N502_1 (TUBULIN BETA CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.49A	3j6gN-5hwqA: undetectable	3j6gN-5hwqA: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6G_P_TA1P502_1 (TUBULIN BETA CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.49A	3j6gP-5hwqA: undetectable	3j6gP-5hwqA: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6G_R_TA1R502_1 (TUBULIN BETA CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.49A	3j6gR-5hwqA: undetectable	3j6gR-5hwqA: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AX8_A_SAMA1474_1 (WBDD)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 6	GLN A 324 ARG A 306 ASP A 365 LEU A 370	SO4 A 506 (-3.6A) None SO4 A 506 ( 4.9A) None	1.16A	4ax8A-5hwqA: 2.0	4ax8A-5hwqA: 22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_A_FOLA703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 11	VAL A 142 ASP A 110 MET A 106 LEU A 102 VAL A 140	None	1.35A	4kyaA-5hwqA: undetectable	4kyaA-5hwqA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_B_FOLB703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	VAL A 142 ASP A 110 MET A 106 LEU A 102 VAL A 140	None	1.19A	4kyaB-5hwqA: undetectable	4kyaB-5hwqA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_D_FOLD703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	VAL A 142 ASP A 110 MET A 106 LEU A 102 VAL A 140	None	1.19A	4kyaD-5hwqA: undetectable	4kyaD-5hwqA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_F_FOLF703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	VAL A 142 ASP A 110 MET A 106 LEU A 102 VAL A 140	None	1.19A	4kyaF-5hwqA: undetectable	4kyaF-5hwqA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_H_FOLH703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	VAL A 142 ASP A 110 MET A 106 LEU A 102 VAL A 140	None	1.17A	4kyaH-5hwqA: undetectable	4kyaH-5hwqA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PXM_B_ESTB2000_1 (ESTROGEN RECEPTOR)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 11	LEU A 337 ALA A 248 LEU A 322 GLY A 302 LEU A 301	None None None GOL A 502 ( 3.8A) GOL A 502 (-4.0A)	1.19A	4pxmB-5hwqA: undetectable	4pxmB-5hwqA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVY_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 10	THR A 53 ALA A 57 ALA A 60 VAL A 96 GLY A 81	None	1.04A	4qvyY-5hwqA: undetectable 4qvyZ-5hwqA: undetectable	4qvyY-5hwqA: 18.96 4qvyZ-5hwqA: 19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZC_E_ACTE406_0 (PROTON-GATED ION CHANNEL)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 5	ILE A 21 ILE A 378 ARG A 28 GLU A 156	None	1.24A	4zzcE-5hwqA: undetectable	4zzcE-5hwqA: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_A_SORA1343_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 6	ARG A 26 ASP A 20 ARG A 42 ILE A 21	None None GOL A 502 ( 2.8A) None	1.35A	5a06A-5hwqA: undetectable	5a06A-5hwqA: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AYF_A_C7HA402_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 5	TYR A 349 GLY A 121 TYR A 116 GLY A 341	None None None CSO A 115 ( 3.3A)	1.04A	5ayfA-5hwqA: undetectable	5ayfA-5hwqA: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXG_B_ESTB601_1 (ESTROGEN RECEPTOR)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 11	LEU A 337 ALA A 248 LEU A 322 GLY A 302 LEU A 301	None None None GOL A 502 ( 3.8A) GOL A 502 (-4.0A)	1.17A	5dxgB-5hwqA: undetectable	5dxgB-5hwqA: 20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E4D_B_BEZB203_0 (HYDROXYNITRILE LYASE)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 4	VAL A 30 ALA A 33 ILE A 21 THR A 36	None CAA A 501 (-3.5A) None None	1.05A	5e4dB-5hwqA: undetectable	5e4dB-5hwqA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GTR_A_ESTA601_1 (ESTROGEN RECEPTOR)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	LEU A 337 ALA A 248 LEU A 322 GLY A 302 LEU A 301	None None None GOL A 502 ( 3.8A) GOL A 502 (-4.0A)	1.01A	5gtrA-5hwqA: undetectable	5gtrA-5hwqA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M54_B_TA1B502_1 (TUBULIN BETA-2B CHAIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	5 / 12	ASP A 110 SER A 144 THR A 405 GLN A 413 LEU A 99	None	1.47A	5m54B-5hwqA: undetectable	5m54B-5hwqA: 23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MFX_A_ACTA701_0 (GENOME POLYPROTEIN)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 5	THR A 312 HIS A 250 ALA A 313 ASP A 145	CSO A 115 ( 3.9A) CSO A 115 (-3.5A) None None	1.30A	5mfxA-5hwqA: undetectable	5mfxA-5hwqA: 23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	3 / 3	SER A 289 SER A 292 ALA A 238	GOL A 505 (-2.4A) None None	0.67A	6dwnC-5hwqA: undetectable	6dwnC-5hwqA: 16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6JI6_A_ACTA305_0 (GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME)	5hwq	HYDROXYMETHYLGLUTARY L-COA SYNTHASE (Myxococcus xanthus)	4 / 5	GLY A 241 LEU A 239 SER A 292 GLN A 296	None	1.20A	6ji6A-5hwqA: undetectable	6ji6A-5hwqA: 18.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4L_B_DCFB853_2","ADENOSINE DEAMINASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"HIS A 250;SER A 144;LEU A  56;GLY A 160","CSO A 115 (-3.5A);None;None;None","1.13A","1a4lB-5hwqA:undetectable","1a4lB-5hwqA:22.49"],["1NT2_A_SAMA301_0","FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ALA A 163;SER A 144;THR A  59;SER A 314;ALA A 320","None","1.02A","1nt2A-5hwqA:undetectable","1nt2A-5hwqA:20.67"],["1SKX_A_RFPA1_2","ORPHAN NUCLEAR RECEPTOR PXR","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"LYS A 259;PHE A 348;LEU A 213;LEU A 322","CAA A 501 (-2.7A);None;None;None","1.21A","1skxA-5hwqA:undetectable","1skxA-5hwqA:21.94"],["1VPO_H_TESH1010_1","ANTI-TESTOSTERONE (HEAVY CHAIN);ANTI-TESTOSTERONE (LIGHT CHAIN)","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"TYR A 349;ALA A 318;TYR A 316;GLY A 321;LEU A 322","None","1.23A","1vpoH-5hwqA:undetectable;1vpoL-5hwqA:undetectable","1vpoH-5hwqA:20.00;1vpoL-5hwqA:17.90"],["2AA6_A_STRA401_1","MINERALOCORTICOID RECEPTOR","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"LEU A 303;LEU A 317;ALA A 318;LEU A  10;MET A 361","None","1.44A","2aa6A-5hwqA:undetectable","2aa6A-5hwqA:21.53"],["2DU8_B_BEZB1352_0","D-AMINO-ACID OXIDASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"LEU A 122;TYR A 349;ILE A   7;GLY A 336","None","0.91A","2du8B-5hwqA:undetectable","2du8B-5hwqA:22.70"],["2IEO_A_017A402_2","PROTEASE;PROTEASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"GLY A 321;ALA A 320;VAL A 164;VAL A  14;VAL A  12","None","0.82A","2ieoB-5hwqA:undetectable","2ieoB-5hwqA:12.62"],["2QL8_A_BEZA143_0","PUTATIVE REDOX PROTEIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"ALA A  58;THR A  59;ALA A  62;ARG A  66","None","0.90A","2ql8A-5hwqA:1.0;2ql8B-5hwqA:undetectable","2ql8A-5hwqA:18.02;2ql8B-5hwqA:18.02"],["2VH3_A_DAHA2_1","RANASMURFIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ALA A  11;ALA A  13;PHE A 402;GLY A 400;ALA A  62","None","1.24A","2vh3A-5hwqA:undetectable","2vh3A-5hwqA:12.68"],["2Y6R_A_CTCA1385_0","TETX2 PROTEIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"MET A 256;PHE A 253;ASN A 304;GLY A  40;PRO A 157","CAA A 501 ( 3.7A);CAA A 501 (-3.6A);None;GOL A 502 (-3.0A);CAA A 501 ( 4.6A)","1.40A","2y6rA-5hwqA:undetectable","2y6rA-5hwqA:23.16"],["3BWC_A_SAMA501_0","SPERMIDINE SYNTHASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ILE A 335;GLY A 336;ASP A 178;GLY A 351;GLN A 296","None","1.05A","3bwcA-5hwqA:undetectable","3bwcA-5hwqA:19.63"],["3E00_A_9CRA7223_1","RETINOIC ACID RECEPTOR RXR-ALPHA","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ALA A 163;ALA A  57;ARG A  63;ALA A  13;ILE A  75","None","1.09A","3e00A-5hwqA:undetectable","3e00A-5hwqA:22.58"],["3J6G_B_TA1B502_1","TUBULIN BETA CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.49A","3j6gB-5hwqA:undetectable","3j6gB-5hwqA:23.52"],["3J6G_D_TA1D502_1","TUBULIN BETA CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.49A","3j6gD-5hwqA:undetectable","3j6gD-5hwqA:23.52"],["3J6G_F_TA1F502_1","TUBULIN BETA CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.49A","3j6gF-5hwqA:undetectable","3j6gF-5hwqA:23.52"],["3J6G_H_TA1H502_1","TUBULIN BETA CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.49A","3j6gH-5hwqA:undetectable","3j6gH-5hwqA:23.52"],["3J6G_J_TA1J502_1","TUBULIN BETA CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.49A","3j6gJ-5hwqA:undetectable","3j6gJ-5hwqA:23.52"],["3J6G_L_TA1L502_1","TUBULIN BETA CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.49A","3j6gL-5hwqA:undetectable","3j6gL-5hwqA:23.52"],["3J6G_N_TA1N502_1","TUBULIN BETA CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.49A","3j6gN-5hwqA:undetectable","3j6gN-5hwqA:23.52"],["3J6G_P_TA1P502_1","TUBULIN BETA CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.49A","3j6gP-5hwqA:undetectable","3j6gP-5hwqA:23.52"],["3J6G_R_TA1R502_1","TUBULIN BETA CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.49A","3j6gR-5hwqA:undetectable","3j6gR-5hwqA:23.52"],["4AX8_A_SAMA1474_1","WBDD","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"GLN A 324;ARG A 306;ASP A 365;LEU A 370","SO4 A 506 (-3.6A);None;SO4 A 506 ( 4.9A);None","1.16A","4ax8A-5hwqA:2.0","4ax8A-5hwqA:22.77"],["4KYA_A_FOLA703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"VAL A 142;ASP A 110;MET A 106;LEU A 102;VAL A 140","None","1.35A","4kyaA-5hwqA:undetectable","4kyaA-5hwqA:21.73"],["4KYA_B_FOLB703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"VAL A 142;ASP A 110;MET A 106;LEU A 102;VAL A 140","None","1.19A","4kyaB-5hwqA:undetectable","4kyaB-5hwqA:21.73"],["4KYA_D_FOLD703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"VAL A 142;ASP A 110;MET A 106;LEU A 102;VAL A 140","None","1.19A","4kyaD-5hwqA:undetectable","4kyaD-5hwqA:21.73"],["4KYA_F_FOLF703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"VAL A 142;ASP A 110;MET A 106;LEU A 102;VAL A 140","None","1.19A","4kyaF-5hwqA:undetectable","4kyaF-5hwqA:21.73"],["4KYA_H_FOLH703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"VAL A 142;ASP A 110;MET A 106;LEU A 102;VAL A 140","None","1.17A","4kyaH-5hwqA:undetectable","4kyaH-5hwqA:21.73"],["4PXM_B_ESTB2000_1","ESTROGEN RECEPTOR","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"LEU A 337;ALA A 248;LEU A 322;GLY A 302;LEU A 301","None;None;None;GOL A 502 ( 3.8A);GOL A 502 (-4.0A)","1.19A","4pxmB-5hwqA:undetectable","4pxmB-5hwqA:20.62"],["4QVY_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"THR A  53;ALA A  57;ALA A  60;VAL A  96;GLY A  81","None","1.04A","4qvyY-5hwqA:undetectable;4qvyZ-5hwqA:undetectable","4qvyY-5hwqA:18.96;4qvyZ-5hwqA:19.04"],["4ZZC_E_ACTE406_0","PROTON-GATED ION CHANNEL","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"ILE A  21;ILE A 378;ARG A  28;GLU A 156","None","1.24A","4zzcE-5hwqA:undetectable","4zzcE-5hwqA:21.23"],["5A06_A_SORA1343_0","ALDOSE-ALDOSE OXIDOREDUCTASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"ARG A  26;ASP A  20;ARG A  42;ILE A  21","None;None;GOL A 502 ( 2.8A);None","1.35A","5a06A-5hwqA:undetectable","5a06A-5hwqA:22.92"],["5AYF_A_C7HA402_1","HISTONE-LYSINE N-METHYLTRANSFERASE SETD7","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"TYR A 349;GLY A 121;TYR A 116;GLY A 341","None;None;None;CSO A 115 ( 3.3A)","1.04A","5ayfA-5hwqA:undetectable","5ayfA-5hwqA:20.87"],["5DXG_B_ESTB601_1","ESTROGEN RECEPTOR","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"LEU A 337;ALA A 248;LEU A 322;GLY A 302;LEU A 301","None;None;None;GOL A 502 ( 3.8A);GOL A 502 (-4.0A)","1.17A","5dxgB-5hwqA:undetectable","5dxgB-5hwqA:20.71"],["5E4D_B_BEZB203_0","HYDROXYNITRILE LYASE","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"VAL A  30;ALA A  33;ILE A  21;THR A  36","None;CAA A 501 (-3.5A);None;None","1.05A","5e4dB-5hwqA:undetectable","5e4dB-5hwqA:20.00"],["5GTR_A_ESTA601_1","ESTROGEN RECEPTOR","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"LEU A 337;ALA A 248;LEU A 322;GLY A 302;LEU A 301","None;None;None;GOL A 502 ( 3.8A);GOL A 502 (-4.0A)","1.01A","5gtrA-5hwqA:undetectable","5gtrA-5hwqA:20.00"],["5M54_B_TA1B502_1","TUBULIN BETA-2B CHAIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",5,"ASP A 110;SER A 144;THR A 405;GLN A 413;LEU A  99","None","1.47A","5m54B-5hwqA:undetectable","5m54B-5hwqA:23.31"],["5MFX_A_ACTA701_0","GENOME POLYPROTEIN","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"THR A 312;HIS A 250;ALA A 313;ASP A 145","CSO A 115 ( 3.9A);CSO A 115 (-3.5A);None;None","1.30A","5mfxA-5hwqA:undetectable","5mfxA-5hwqA:23.75"],["6DWN_C_AQ4C602_1","CYTOCHROME P450 1A1","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",3,"SER A 289;SER A 292;ALA A 238","GOL A 505 (-2.4A);None;None","0.67A","6dwnC-5hwqA:undetectable","6dwnC-5hwqA:16.21"],["6JI6_A_ACTA305_0","GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME","5hwq","HYDROXYMETHYLGLUTARYL-COA SYNTHASE","Myxococcus xanthus",4,"GLY A 241;LEU A 239;SER A 292;GLN A 296","None","1.20A","6ji6A-5hwqA:undetectable","6ji6A-5hwqA:18.03"]]