SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hxg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 5hxg FLAGELLAR
TRANSCRIPTIONAL
REGULATOR FLHD
(Salmonella
enterica) 		4 / 4 ILE B  28
MET B  45
VAL B  67
GLY B  50
 None
 1.26A 1e06B-5hxgB:
undetectable		 1e06B-5hxgB:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5hxg UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		4 / 7 VAL A 101
VAL A  85
LEU A  84
LEU A 103
 None
 0.78A 1pthA-5hxgA:
undetectable		 1pthA-5hxgA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5hxg UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		4 / 7 VAL A 101
VAL A  85
LEU A  84
LEU A 103
 None
 0.77A 1pthB-5hxgA:
undetectable		 1pthB-5hxgA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5hxg UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		5 / 12 LEU A 146
ALA A 141
GLY A 137
GLU A 107
LEU A 173
 None
 1.26A 2a58A-5hxgA:
undetectable
2a58B-5hxgA:
undetectable		 2a58A-5hxgA:
23.05
2a58B-5hxgA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5hxg UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		5 / 12 LEU A 146
ALA A 141
GLY A 137
GLU A 107
LEU A 173
 None
 1.26A 2a58B-5hxgA:
undetectable
2a58C-5hxgA:
undetectable		 2a58B-5hxgA:
23.05
2a58C-5hxgA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5hxg UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		5 / 12 LEU A 146
ALA A 141
GLY A 137
GLU A 107
LEU A 173
 None
 1.26A 2a58D-5hxgA:
undetectable
2a58E-5hxgA:
undetectable		 2a58D-5hxgA:
23.05
2a58E-5hxgA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 5hxg UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		5 / 11 ALA A  82
VAL A 105
ILE A 121
VAL A  75
ILE A  77
 None
 0.88A 3ekxB-5hxgA:
undetectable		 3ekxB-5hxgA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_1
(DIHYDROFOLATE
REDUCTASE)		 5hxg FLAGELLAR
TRANSCRIPTIONAL
REGULATOR FLHD
UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		5 / 12 ALA B  61
LEU B  22
GLN B  25
ILE A 177
LEU A 136
 None
 1.25A 3ia4C-5hxgB:
undetectable		 3ia4C-5hxgB:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 5hxg FLAGELLAR
TRANSCRIPTIONAL
REGULATOR FLHD
UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		5 / 11 LEU A 146
LEU A 133
GLU A 107
LEU B  54
LEU A 156
 None
 1.40A 3ndvC-5hxgA:
undetectable
3ndvD-5hxgA:
undetectable		 3ndvC-5hxgA:
20.42
3ndvD-5hxgA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 5hxg UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		4 / 5 VAL A 101
LEU A  95
LEU A  56
ILE A  77
 None
 0.97A 4a9jA-5hxgA:
undetectable		 4a9jA-5hxgA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5hxg FLAGELLAR
TRANSCRIPTIONAL
REGULATOR FLHD
UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		5 / 12 LEU A 146
VAL A 154
ILE A 184
LEU B  18
LEU A 173
 None
 1.37A 4yvpB-5hxgA:
5.0		 4yvpB-5hxgA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 5hxg UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		5 / 12 GLY A  80
ASN A  76
GLN A 104
LEU A 103
LEU A 124
 None
 1.00A 5nwwA-5hxgA:
undetectable		 5nwwA-5hxgA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 5hxg FLAGELLAR
TRANSCRIPTIONAL
REGULATOR FLHD
UNCHARACTERIZED
PROTEIN STM1697
(Salmonella
enterica) 		5 / 12 LEU B  22
VAL B  58
LEU B  18
ILE A 184
LEU A 146
 None
 1.12A 5og9B-5hxgB:
undetectable		 5og9B-5hxgB:
15.17