SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hxw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 9 GLY A 437
GLY A  63
LEU A  65
SER A  93
GLY A 257
 16A  A 504 ( 3.8A)
FAD  A 501 (-3.3A)
FAD  A 501 (-3.7A)
FAD  A 501 (-2.5A)
FAD  A 501 (-3.4A)
 1.07A 1l4nA-5hxwA:
undetectable		 1l4nA-5hxwA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_F_H4BF1005_1
(HYPOTHETICAL PROTEIN
PH0634)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 9 ILE A 420
ASP A 416
HIS A 113
THR A 436
GLU A 442
 None
None
None
FAD  A 501 (-4.0A)
None
 1.46A 2dttE-5hxwA:
undetectable
2dttF-5hxwA:
undetectable		 2dttE-5hxwA:
14.54
2dttF-5hxwA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 10 LYS A 215
GLU A 212
GLU A  45
ILE A 221
ILE A  88
 None
 1.31A 2j9dD-5hxwA:
2.0
2j9dE-5hxwA:
1.7
2j9dF-5hxwA:
2.0		 2j9dD-5hxwA:
13.50
2j9dE-5hxwA:
13.50
2j9dF-5hxwA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		3 / 3 ARG A 220
VAL A 252
THR A 249
 None
 0.62A 2nmzA-5hxwA:
undetectable		 2nmzA-5hxwA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 11 LEU A 430
VAL A  58
ILE A 247
VAL A 254
VAL A 252
 None
 0.95A 2nnpB-5hxwA:
undetectable		 2nnpB-5hxwA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  98
GLY A 437
GLY A 439
THR A 436
ILE A 413
 FAD  A 501 (-3.8A)
16A  A 504 ( 3.8A)
FAD  A 501 (-3.1A)
FAD  A 501 (-4.0A)
16A  A 504 ( 4.1A)
 0.84A 2oxtA-5hxwA:
undetectable		 2oxtA-5hxwA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  98
GLY A 437
GLY A 439
THR A 436
ILE A 413
 FAD  A 501 (-3.8A)
16A  A 504 ( 3.8A)
FAD  A 501 (-3.1A)
FAD  A 501 (-4.0A)
16A  A 504 ( 4.1A)
 0.79A 2oxtB-5hxwA:
2.4		 2oxtB-5hxwA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.90A 2pxcA-5hxwA:
2.4		 2pxcA-5hxwA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		4 / 7 PHE A 201
ALA A 100
THR A 436
LEU A  65
 None
None
FAD  A 501 (-4.0A)
FAD  A 501 (-3.7A)
 0.93A 2wx2A-5hxwA:
undetectable		 2wx2A-5hxwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 9 ALA A 276
GLY A 409
PRO A 314
VAL A 316
ILE A 317
 16A  A 504 ( 3.9A)
FAD  A 501 (-3.7A)
None
None
16A  A 504 ( 4.7A)
 1.08A 3em4B-5hxwA:
undetectable		 3em4B-5hxwA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		3 / 3 ARG A 220
VAL A 252
THR A 249
 None
 0.79A 3k4vD-5hxwA:
undetectable		 3k4vD-5hxwA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.88A 3p97A-5hxwA:
undetectable		 3p97A-5hxwA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.85A 3p97C-5hxwA:
undetectable		 3p97C-5hxwA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		4 / 5 VAL A 271
LEU A 468
ILE A 420
VAL A 254
 None
 0.97A 4a9kB-5hxwA:
undetectable		 4a9kB-5hxwA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		4 / 7 ASP A 165
SER A 164
GLU A 122
HIS A 118
 None
 0.91A 4aq7A-5hxwA:
undetectable		 4aq7A-5hxwA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.85A 4ctjA-5hxwA:
undetectable		 4ctjA-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.86A 4ctjC-5hxwA:
2.5		 4ctjC-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.86A 4ctkA-5hxwA:
undetectable		 4ctkA-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.83A 4ctkC-5hxwA:
undetectable		 4ctkC-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 9 ALA A 276
GLY A 409
PRO A 314
VAL A 316
ILE A 317
 16A  A 504 ( 3.9A)
FAD  A 501 (-3.7A)
None
None
16A  A 504 ( 4.7A)
 1.23A 4ll3B-5hxwA:
undetectable		 4ll3B-5hxwA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		4 / 4 LEU A 449
VAL A 445
GLU A 448
ARG A 119
 None
 1.41A 4ww7A-5hxwA:
undetectable		 4ww7A-5hxwA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		6 / 12 PHE A 208
GLY A  90
ALA A  89
ILE A  67
ILE A 221
THR A 207
 None
 1.22A 4xdrA-5hxwA:
1.1		 4xdrA-5hxwA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		4 / 6 ILE A 317
PHE A 341
ILE A 413
GLU A 417
 16A  A 504 ( 4.7A)
None
16A  A 504 ( 4.1A)
16A  A 504 (-4.0A)
 1.07A 4zzcA-5hxwA:
undetectable
4zzcB-5hxwA:
undetectable		 4zzcA-5hxwA:
21.83
4zzcB-5hxwA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		4 / 6 ILE A 317
PHE A 341
ILE A 413
GLU A 417
 16A  A 504 ( 4.7A)
None
16A  A 504 ( 4.1A)
16A  A 504 (-4.0A)
 1.09A 4zzcB-5hxwA:
undetectable
4zzcC-5hxwA:
undetectable		 4zzcB-5hxwA:
21.83
4zzcC-5hxwA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		4 / 6 ASP A 202
THR A 132
TYR A 133
SER A 200
 None
 1.50A 5b6iB-5hxwA:
2.5		 5b6iB-5hxwA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.85A 5e9qA-5hxwA:
2.3		 5e9qA-5hxwA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.86A 5e9qC-5hxwA:
2.5		 5e9qC-5hxwA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.87A 5ec8A-5hxwA:
2.3		 5ec8A-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.84A 5ec8C-5hxwA:
undetectable		 5ec8C-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.86A 5ehgA-5hxwA:
undetectable		 5ehgA-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.84A 5ehgC-5hxwA:
undetectable		 5ehgC-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.85A 5eifA-5hxwA:
undetectable		 5eifA-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.86A 5eifC-5hxwA:
undetectable		 5eifC-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.85A 5ekxB-5hxwA:
undetectable		 5ekxB-5hxwA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.89A 5ikmA-5hxwA:
undetectable		 5ikmA-5hxwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		3 / 3 PRO A 465
ARG A 470
GLU A 108
 None
 0.79A 5j6hA-5hxwA:
undetectable		 5j6hA-5hxwA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.89A 5kqrA-5hxwA:
undetectable		 5kqrA-5hxwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.89A 5kqsA-5hxwA:
undetectable		 5kqsA-5hxwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.88A 5m5bA-5hxwA:
2.1		 5m5bA-5hxwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.89A 5njvA-5hxwA:
undetectable		 5njvA-5hxwA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.87A 5njvB-5hxwA:
undetectable		 5njvB-5hxwA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.84A 5vimA-5hxwA:
2.0		 5vimA-5hxwA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.87A 5vimB-5hxwA:
2.0		 5vimB-5hxwA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.81A 5wz1B-5hxwA:
undetectable		 5wz1B-5hxwA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.88A 5wz2A-5hxwA:
undetectable		 5wz2A-5hxwA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.88A 5wz2B-5hxwA:
undetectable		 5wz2B-5hxwA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 GLY A  66
GLY A 257
GLY A  61
VAL A 271
ILE A 420
 None
FAD  A 501 (-3.4A)
FAD  A 501 (-3.1A)
None
None
 0.90A 5wz2C-5hxwA:
undetectable		 5wz2C-5hxwA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		4 / 5 VAL A 236
PRO A 428
GLY A 429
TYR A 427
 None
 1.39A 5x80A-5hxwA:
undetectable
5x80B-5hxwA:
undetectable		 5x80A-5hxwA:
16.37
5x80B-5hxwA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 5hxw L-AMINO ACID
DEAMINASE
(Proteus
vulgaris) 		5 / 12 VAL A 151
PRO A 290
GLN A 136
PRO A 297
ILE A 300
 None
 1.13A 6becA-5hxwA:
undetectable
6becB-5hxwA:
undetectable
6becC-5hxwA:
undetectable		 6becA-5hxwA:
22.96
6becB-5hxwA:
22.96
6becC-5hxwA:
22.96