SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hy6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5hy6 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5A
(Spodoptera
frugiperda) 		4 / 4 LEU A 102
LEU A 122
GLN A  92
GLU A  89
 None
 1.19A 4i41A-5hy6A:
undetectable		 4i41A-5hy6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 5hy6 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5A
(Spodoptera
frugiperda) 		5 / 12 PHE A  32
CYH A  40
GLY A  68
ARG A  88
LEU A 141
 None
 1.38A 4kotA-5hy6A:
undetectable		 4kotA-5hy6A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5hy6 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5A
(Spodoptera
frugiperda) 		3 / 3 CYH A  75
MET A  81
ASN A  80
 None
 0.96A 5qh8A-5hy6A:
undetectable		 5qh8A-5hy6A:
19.80