SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hyh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 8 SER A 243
ALA A 113
PHE A 117
ILE A 112
 None
 1.16A 1gm7A-5hyhA:
undetectable
1gm7B-5hyhA:
undetectable		 1gm7A-5hyhA:
18.93
1gm7B-5hyhA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 11 LEU A 326
VAL A 325
LYS A 248
VAL A 267
GLN A 328
 None
 1.21A 1gx9A-5hyhA:
undetectable		 1gx9A-5hyhA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 7 LEU A 195
ILE A 206
THR A 202
MET A 323
 None
 1.07A 1kglA-5hyhA:
undetectable		 1kglA-5hyhA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 7 PHE A 166
ARG A  92
ILE A 284
ILE A  74
 None
 0.91A 1oniD-5hyhA:
undetectable
1oniF-5hyhA:
undetectable		 1oniD-5hyhA:
17.73
1oniF-5hyhA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 10 GLU A 109
GLU A 144
ILE A 108
GLU A 236
ILE A 208
 FE  A 401 (-2.8A)
FE  A 402 ( 2.3A)
None
FE  A 402 ( 2.0A)
None
 1.39A 2j9dD-5hyhA:
undetectable
2j9dE-5hyhA:
0.0
2j9dF-5hyhA:
0.0		 2j9dD-5hyhA:
16.04
2j9dE-5hyhA:
17.57
2j9dF-5hyhA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 6 ILE A 206
SER A 243
ILE A 108
PHE A 273
 None
 1.12A 2q72A-5hyhA:
undetectable		 2q72A-5hyhA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 12 LEU A  94
SER A  95
PHE A  69
ILE A  74
SER A 164
 None
 1.09A 3ko0A-5hyhA:
undetectable
3ko0B-5hyhA:
undetectable
3ko0C-5hyhA:
undetectable
3ko0D-5hyhA:
undetectable		 3ko0A-5hyhA:
14.19
3ko0B-5hyhA:
14.19
3ko0C-5hyhA:
14.19
3ko0D-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 11 SER A 164
LEU A  94
SER A  95
PHE A  69
ILE A  74
 None
 1.10A 3ko0A-5hyhA:
undetectable
3ko0B-5hyhA:
undetectable
3ko0C-5hyhA:
undetectable
3ko0D-5hyhA:
undetectable		 3ko0A-5hyhA:
14.19
3ko0B-5hyhA:
14.19
3ko0C-5hyhA:
14.19
3ko0D-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 11 LEU A  94
SER A  95
PHE A  69
ILE A  74
SER A 164
 None
 1.11A 3ko0C-5hyhA:
undetectable
3ko0D-5hyhA:
undetectable
3ko0E-5hyhA:
undetectable
3ko0F-5hyhA:
undetectable		 3ko0C-5hyhA:
14.19
3ko0D-5hyhA:
14.19
3ko0E-5hyhA:
14.19
3ko0F-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 11 SER A 164
LEU A  94
SER A  95
PHE A  69
ILE A  74
 None
 1.14A 3ko0C-5hyhA:
undetectable
3ko0D-5hyhA:
undetectable
3ko0E-5hyhA:
undetectable
3ko0F-5hyhA:
undetectable		 3ko0C-5hyhA:
14.19
3ko0D-5hyhA:
14.19
3ko0E-5hyhA:
14.19
3ko0F-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 11 LEU A  94
SER A  95
PHE A  69
ILE A  74
SER A 164
 None
 1.08A 3ko0E-5hyhA:
undetectable
3ko0F-5hyhA:
undetectable
3ko0G-5hyhA:
undetectable
3ko0H-5hyhA:
undetectable		 3ko0E-5hyhA:
14.19
3ko0F-5hyhA:
14.19
3ko0G-5hyhA:
14.19
3ko0H-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 12 LEU A  94
SER A  95
PHE A  69
ILE A  74
SER A 164
 None
 1.13A 3ko0G-5hyhA:
undetectable
3ko0H-5hyhA:
undetectable
3ko0I-5hyhA:
undetectable
3ko0J-5hyhA:
undetectable		 3ko0G-5hyhA:
14.19
3ko0H-5hyhA:
14.19
3ko0I-5hyhA:
14.19
3ko0J-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 12 SER A  95
PHE A  69
ILE A  74
PHE A 166
SER A 164
 None
 1.21A 3ko0G-5hyhA:
undetectable
3ko0H-5hyhA:
undetectable
3ko0I-5hyhA:
undetectable
3ko0J-5hyhA:
undetectable		 3ko0G-5hyhA:
14.19
3ko0H-5hyhA:
14.19
3ko0I-5hyhA:
14.19
3ko0J-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 11 SER A 164
LEU A  94
SER A  95
PHE A  69
ILE A  74
 None
 1.13A 3ko0A-5hyhA:
undetectable
3ko0B-5hyhA:
undetectable
3ko0I-5hyhA:
undetectable
3ko0J-5hyhA:
undetectable		 3ko0A-5hyhA:
14.19
3ko0B-5hyhA:
14.19
3ko0I-5hyhA:
14.19
3ko0J-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 12 LEU A  94
SER A  95
PHE A  69
ILE A  74
SER A 164
 None
 1.15A 3ko0K-5hyhA:
undetectable
3ko0L-5hyhA:
undetectable
3ko0M-5hyhA:
undetectable
3ko0N-5hyhA:
undetectable		 3ko0K-5hyhA:
14.19
3ko0L-5hyhA:
14.19
3ko0M-5hyhA:
14.19
3ko0N-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 12 LEU A  94
SER A  95
PHE A  69
ILE A  74
SER A 164
 None
 1.04A 3ko0M-5hyhA:
undetectable
3ko0N-5hyhA:
undetectable
3ko0O-5hyhA:
undetectable
3ko0P-5hyhA:
undetectable		 3ko0M-5hyhA:
14.19
3ko0N-5hyhA:
14.19
3ko0O-5hyhA:
14.19
3ko0P-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 11 SER A 164
LEU A  94
SER A  95
PHE A  69
ILE A  74
 None
 1.15A 3ko0K-5hyhA:
undetectable
3ko0L-5hyhA:
undetectable
3ko0M-5hyhA:
undetectable
3ko0N-5hyhA:
undetectable		 3ko0K-5hyhA:
14.19
3ko0L-5hyhA:
14.19
3ko0M-5hyhA:
14.19
3ko0N-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 12 SER A 164
LEU A  94
SER A  95
PHE A  69
ILE A  74
 None
 1.02A 3ko0M-5hyhA:
undetectable
3ko0N-5hyhA:
undetectable
3ko0O-5hyhA:
undetectable
3ko0P-5hyhA:
undetectable		 3ko0M-5hyhA:
14.19
3ko0N-5hyhA:
14.19
3ko0O-5hyhA:
14.19
3ko0P-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 11 SER A  95
PHE A  69
ILE A  74
SER A 164
PHE A 166
 None
 1.20A 3ko0Q-5hyhA:
0.0
3ko0R-5hyhA:
0.0
3ko0S-5hyhA:
0.0
3ko0T-5hyhA:
undetectable		 3ko0Q-5hyhA:
14.19
3ko0R-5hyhA:
14.19
3ko0S-5hyhA:
14.19
3ko0T-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 11 SER A 164
LEU A  94
SER A  95
PHE A  69
ILE A  74
 None
 1.18A 3ko0Q-5hyhA:
undetectable
3ko0R-5hyhA:
undetectable
3ko0S-5hyhA:
undetectable
3ko0T-5hyhA:
undetectable		 3ko0Q-5hyhA:
14.19
3ko0R-5hyhA:
14.19
3ko0S-5hyhA:
14.19
3ko0T-5hyhA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		3 / 3 VAL A 142
VAL A 137
TRP A  45
 None
 0.95A 3l8lC-5hyhA:
undetectable
3l8lD-5hyhA:
undetectable		 3l8lC-5hyhA:
4.78
3l8lD-5hyhA:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 7 TYR A 101
ASN A 233
LEU A 212
ASP A 213
 None
None
None
TLA  A 403 (-3.2A)
 1.24A 3lslA-5hyhA:
undetectable
3lslD-5hyhA:
undetectable		 3lslA-5hyhA:
23.44
3lslD-5hyhA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 7 TYR A 101
ASN A 233
LEU A 212
ASP A 213
 None
None
None
TLA  A 403 (-3.2A)
 1.19A 3lslA-5hyhA:
undetectable
3lslD-5hyhA:
undetectable		 3lslA-5hyhA:
23.44
3lslD-5hyhA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 6 TYR A 101
ASN A 233
LEU A 212
ASP A 213
 None
None
None
TLA  A 403 (-3.2A)
 1.20A 3lslG-5hyhA:
undetectable		 3lslG-5hyhA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 5 ASP A 277
ILE A  74
PRO A  75
PHE A  76
 None
 0.89A 3s3vA-5hyhA:
undetectable		 3s3vA-5hyhA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 5 ILE A 179
THR A 178
THR A 177
SER A 174
 None
 1.01A 3snfA-5hyhA:
undetectable		 3snfA-5hyhA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 7 VAL A 290
LEU A  85
SER A  86
GLU A  88
 None
 1.08A 4zphA-5hyhA:
undetectable
4zphB-5hyhA:
undetectable		 4zphA-5hyhA:
20.29
4zphB-5hyhA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		3 / 3 TRP A  82
GLU A  71
ASP A  87
 None
 0.86A 5gqbA-5hyhA:
undetectable		 5gqbA-5hyhA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 8 LEU A 195
ILE A 206
THR A 202
MET A 323
 None
 0.98A 5ljbA-5hyhA:
undetectable		 5ljbA-5hyhA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJD_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 9 LEU A 195
ILE A 206
THR A 202
LEU A 320
MET A 323
 None
 1.31A 5ljdA-5hyhA:
undetectable		 5ljdA-5hyhA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 6 LEU A 195
ILE A 206
THR A 202
MET A 323
 None
 1.02A 5ljeA-5hyhA:
undetectable		 5ljeA-5hyhA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 12 SER A 207
VAL A 325
ALA A 240
LEU A 262
VAL A 266
 None
 1.11A 5tudA-5hyhA:
1.7		 5tudA-5hyhA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		5 / 12 SER A 207
VAL A 325
ALA A 240
LEU A 262
VAL A 266
 None
 1.07A 5tudD-5hyhA:
4.1		 5tudD-5hyhA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 5hyh UNCHARACTERIZED
PROTEIN
(Streptomyces
venezuelae) 		4 / 5 ASN A 225
ASP A  68
SER A  95
ARG A 162
 None
 1.42A 5w4zA-5hyhA:
undetectable		 5w4zA-5hyhA:
14.01