SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_2
(MINERALOCORTICOID
RECEPTOR)		 5i01 PHOSPHOHEPTOSE
ISOMERASE
(Neisseria
gonorrhoeae) 		4 / 4 LEU A  41
LEU A  36
MET A  66
MET A 185
 None
 1.26A 2oaxB-5i01A:
0.0		 2oaxB-5i01A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 5i01 PHOSPHOHEPTOSE
ISOMERASE
(Neisseria
gonorrhoeae) 		5 / 12 ALA A  18
GLY A 147
PRO A 169
ILE A 153
LEU A 163
 None
 0.93A 2plwA-5i01A:
undetectable		 2plwA-5i01A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 5i01 PHOSPHOHEPTOSE
ISOMERASE
(Neisseria
gonorrhoeae) 		3 / 3 GLU A  65
GLY A  68
THR A  67
 ZN  A 301 (-2.4A)
None
None
 0.50A 3iazA-5i01A:
undetectable		 3iazA-5i01A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_B_ACTB600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5i01 PHOSPHOHEPTOSE
ISOMERASE
(Neisseria
gonorrhoeae) 		4 / 5 ARG A   7
HIS A  11
ALA A  10
GLU A  14
 None
 1.43A 3mbgB-5i01A:
undetectable
3mbgC-5i01A:
undetectable		 3mbgB-5i01A:
19.12
3mbgC-5i01A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 5i01 PHOSPHOHEPTOSE
ISOMERASE
(Neisseria
gonorrhoeae) 		5 / 9 LEU A  26
VAL A 162
GLY A 118
ILE A 119
THR A  30
 None
 1.19A 3spkA-5i01A:
undetectable		 3spkA-5i01A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 5i01 PHOSPHOHEPTOSE
ISOMERASE
(Neisseria
gonorrhoeae) 		4 / 7 VAL A 132
MET A 156
LEU A 157
ASP A 161
 None
 1.11A 4hxyB-5i01A:
undetectable		 4hxyB-5i01A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5i01 PHOSPHOHEPTOSE
ISOMERASE
(Neisseria
gonorrhoeae) 		5 / 12 GLY A  51
LEU A  26
GLY A 147
SER A 122
ILE A 174
 None
 1.15A 5vooA-5i01A:
2.3		 5vooA-5i01A:
26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 5i01 PHOSPHOHEPTOSE
ISOMERASE
(Neisseria
gonorrhoeae) 		5 / 10 LEU A  36
ALA A  33
ILE A 119
HIS A 178
LEU A 181
 None
 1.37A 6cbzB-5i01A:
undetectable		 6cbzB-5i01A:
19.31