SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i0c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)
5i0c UNCHARACTERIZED
PROTEIN YJDJ

(Escherichia
coli)
4 / 5 GLY A  50
LYS A  51
GLU A  78
GLY A  48
PO4  A 105 (-3.4A)
None
None
None
0.48A 3onnA-5i0cA:
undetectable
3onnA-5i0cA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)
5i0c UNCHARACTERIZED
PROTEIN YJDJ

(Escherichia
coli)
3 / 3 PRO A  27
ASN A   8
HIS A   7
None
0.83A 4ma3H-5i0cA:
undetectable
4ma3L-5i0cA:
undetectable
4ma3H-5i0cA:
16.67
4ma3L-5i0cA:
17.13