SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i1f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		4 / 6 PHE A 184
GLU A 161
ARG A 178
ILE A 174
 None
 1.39A 1nsiC-5i1fA:
undetectable
1nsiD-5i1fA:
undetectable		 1nsiC-5i1fA:
20.68
1nsiD-5i1fA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		3 / 3 ASP A 133
GLU A 228
ARG A  59
 MG  A 303 ( 2.6A)
MG  A 302 ( 3.9A)
None
 0.61A 1wopA-5i1fA:
undetectable		 1wopA-5i1fA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		4 / 6 LEU A 238
GLN A 243
LEU A 239
GLU A 242
 None
None
None
CL  A 306 ( 4.5A)
 0.75A 3h5gB-5i1fA:
undetectable
3h5gC-5i1fA:
undetectable		 3h5gB-5i1fA:
7.28
3h5gC-5i1fA:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		5 / 10 PRO A  10
HIS A 113
GLY A 112
GLY A  58
ALA A  12
 UPG  A 301 (-4.3A)
None
None
None
UPG  A 301 (-3.2A)
 1.13A 3pp7B-5i1fA:
4.6		 3pp7B-5i1fA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		4 / 7 GLU A 161
PHE A 202
TYR A 249
VAL A 149
 None
 1.06A 4a97D-5i1fA:
undetectable		 4a97D-5i1fA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		4 / 7 GLU A 162
GLU A 161
PHE A 202
VAL A 149
 None
 1.01A 4a97D-5i1fA:
undetectable		 4a97D-5i1fA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		4 / 6 GLU A 161
PHE A 202
TYR A 249
VAL A 149
 None
 1.16A 4a97E-5i1fA:
undetectable		 4a97E-5i1fA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		3 / 3 LYS A 213
LYS A 211
PRO A 212
 None
None
CL  A 306 (-3.6A)
 1.24A 4dv1L-5i1fA:
undetectable		 4dv1L-5i1fA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		5 / 12 LEU A 136
LEU A 111
ILE A 235
ALA A 128
LEU A 210
 None
UPG  A 301 (-3.6A)
None
None
None
 1.31A 5ienA-5i1fA:
undetectable		 5ienA-5i1fA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		5 / 10 VAL A 160
GLY A 203
GLY A 172
ILE A 235
ALA A 246
 None
None
UPG  A 301 (-3.3A)
None
None
 0.86A 5vm8B-5i1fA:
undetectable		 5vm8B-5i1fA:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE
(Burkholderia
vietnamiensis) 		4 / 5 PRO A 126
VAL A   4
GLY A 206
VAL A 157
 CL  A 305 (-3.9A)
None
UPG  A 301 ( 4.3A)
None
 0.97A 6ak3B-5i1fA:
undetectable		 6ak3B-5i1fA:
13.04