SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i2h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 10 PHE A 257
PRO A 256
VAL A 254
ILE A 222
GLY A 250
None
1.49A 13gsA-5i2hA:
undetectable
13gsA-5i2hA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_B_SASB211_1
(GLUTATHIONE
S-TRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 9 PHE A 257
PRO A 256
VAL A 254
ILE A 222
GLY A 250
None
1.49A 13gsB-5i2hA:
undetectable
13gsB-5i2hA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 7 VAL A  39
LEU A 123
VAL A 120
LEU A  71
None
0.84A 1cqpA-5i2hA:
2.7
1cqpB-5i2hA:
2.7
1cqpA-5i2hA:
18.86
1cqpB-5i2hA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
3 / 4 VAL A 281
TRP A 272
TRP A 335
None
1.11A 1gmkC-5i2hA:
undetectable
1gmkD-5i2hA:
undetectable
1gmkC-5i2hA:
7.89
1gmkD-5i2hA:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 11 VAL A 176
LEU A 177
ALA A 174
ALA A 210
LEU A 264
None
1.08A 1jinA-5i2hA:
undetectable
1jinA-5i2hA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.22A 1kifA-5i2hA:
3.1
1kifA-5i2hA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.22A 1kifB-5i2hA:
3.1
1kifB-5i2hA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.22A 1kifC-5i2hA:
3.1
1kifC-5i2hA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.22A 1kifD-5i2hA:
3.1
1kifD-5i2hA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.22A 1kifE-5i2hA:
3.1
1kifE-5i2hA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.22A 1kifF-5i2hA:
3.1
1kifF-5i2hA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.22A 1kifG-5i2hA:
3.1
1kifG-5i2hA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.22A 1kifH-5i2hA:
3.1
1kifH-5i2hA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 GLY A 220
ALA A 236
THR A 208
GLY A 202
ALA A 232
None
0.97A 1utdL-5i2hA:
undetectable
1utdM-5i2hA:
undetectable
1utdL-5i2hA:
12.43
1utdM-5i2hA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 11 GLY A 220
ALA A 236
THR A 208
GLY A 202
ALA A 232
None
0.97A 1utdP-5i2hA:
undetectable
1utdQ-5i2hA:
undetectable
1utdP-5i2hA:
12.43
1utdQ-5i2hA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 GLY A 202
GLY A 203
ASP A 251
SER A 266
TRP A 272
None
None
EDO  A 504 (-3.8A)
None
None
0.75A 1xdsA-5i2hA:
19.3
1xdsA-5i2hA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 GLY A 202
GLY A 203
ASP A 251
SER A 266
TRP A 272
None
None
EDO  A 504 (-3.8A)
None
None
0.68A 1xdsB-5i2hA:
14.0
1xdsB-5i2hA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 9 LEU A  71
PHE A  40
LEU A  67
LEU A  57
ALA A  32
None
1.35A 2bxeA-5i2hA:
undetectable
2bxeA-5i2hA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.24A 2du8G-5i2hA:
3.1
2du8G-5i2hA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.37A 2du8J-5i2hA:
3.1
2du8J-5i2hA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 7 GLY A 203
TYR A 207
ASP A 224
ASP A 251
None
None
EDO  A 504 (-4.0A)
EDO  A 504 (-3.8A)
1.01A 2g72B-5i2hA:
13.4
2g72B-5i2hA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 9 LEU A  95
LEU A  71
ALA A  31
LEU A  29
ALA A  26
None
1.30A 2vcvE-5i2hA:
undetectable
2vcvE-5i2hA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 6 ARG A 293
LEU A 295
PHE A 173
LEU A 177
None
0.99A 3abkP-5i2hA:
undetectable
3abkW-5i2hA:
undetectable
3abkP-5i2hA:
22.46
3abkW-5i2hA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 7 ARG A 293
LEU A 295
PHE A 173
LEU A 177
None
1.04A 3asnP-5i2hA:
undetectable
3asnW-5i2hA:
undetectable
3asnP-5i2hA:
22.46
3asnW-5i2hA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 7 ARG A 293
LEU A 295
PHE A 173
LEU A 177
None
1.05A 3asoP-5i2hA:
undetectable
3asoW-5i2hA:
undetectable
3asoP-5i2hA:
22.46
3asoW-5i2hA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 ILE A 222
GLY A 205
ALA A 163
ALA A 210
ILE A 231
None
1.00A 3jayA-5i2hA:
undetectable
3jayA-5i2hA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 9 LEU A  71
LEU A 119
ALA A  26
GLU A  28
ALA A  32
None
1.13A 3mdvA-5i2hA:
undetectable
3mdvA-5i2hA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 ALA A  35
LEU A  37
LEU A  67
ALA A  32
LEU A  30
None
1.17A 3r9cA-5i2hA:
undetectable
3r9cA-5i2hA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 6 ARG A 293
LEU A 295
PHE A 173
LEU A 177
None
1.02A 3wg7C-5i2hA:
undetectable
3wg7J-5i2hA:
undetectable
3wg7C-5i2hA:
22.46
3wg7J-5i2hA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 LEU A 162
GLY A 202
VAL A 228
ASP A 271
TRP A 272
None
None
None
AGI  A 501 (-2.4A)
None
0.81A 4a6eA-5i2hA:
22.0
4a6eA-5i2hA:
27.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 LEU A 162
GLY A 203
VAL A 228
ASP A 271
TRP A 272
None
None
None
AGI  A 501 (-2.4A)
None
0.71A 4a6eA-5i2hA:
22.0
4a6eA-5i2hA:
27.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 4 ILE A 206
ASP A 199
ARG A 165
THR A 208
None
None
AGI  A 501 (-2.8A)
None
1.44A 4nx6A-5i2hA:
undetectable
4nx6A-5i2hA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_1
(DIHYDROFOLATE
REDUCTASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 4 ILE A 206
ASP A 199
ARG A 165
THR A 208
None
None
AGI  A 501 (-2.8A)
None
1.44A 4nx7A-5i2hA:
undetectable
4nx7A-5i2hA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 11 ARG A  56
LEU A  43
LEU A  67
LEU A  48
LEU A  77
None
1.46A 4or0A-5i2hA:
undetectable
4or0A-5i2hA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 11 LEU A  29
SER A  33
LEU A  77
LEU A 313
LEU A  67
None
1.20A 4or0A-5i2hA:
undetectable
4or0A-5i2hA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
6 / 12 ASP A 199
ASP A 224
ASP A 251
MET A 252
ASP A 271
TRP A 272
None
EDO  A 504 (-4.0A)
EDO  A 504 (-3.8A)
EDO  A 504 (-3.9A)
AGI  A 501 (-2.4A)
None
0.61A 4pghB-5i2hA:
19.1
4pghB-5i2hA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_C_SAMC401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 11 ASP A 224
VAL A 228
ASP A 251
MET A 252
TRP A 272
EDO  A 504 (-4.0A)
None
EDO  A 504 (-3.8A)
EDO  A 504 (-3.9A)
None
0.62A 4pghC-5i2hA:
19.6
4pghC-5i2hA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.23A 4qvpH-5i2hA:
undetectable
4qvpI-5i2hA:
undetectable
4qvpH-5i2hA:
21.43
4qvpI-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.22A 4qvpV-5i2hA:
undetectable
4qvpW-5i2hA:
undetectable
4qvpV-5i2hA:
21.43
4qvpW-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.22A 4qvyV-5i2hA:
undetectable
4qvyW-5i2hA:
undetectable
4qvyV-5i2hA:
21.43
4qvyW-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 11 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.23A 4qw0H-5i2hA:
undetectable
4qw0I-5i2hA:
undetectable
4qw0H-5i2hA:
21.43
4qw0I-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 11 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.23A 4qw0V-5i2hA:
undetectable
4qw0W-5i2hA:
undetectable
4qw0V-5i2hA:
21.43
4qw0W-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.23A 4qw1H-5i2hA:
undetectable
4qw1I-5i2hA:
undetectable
4qw1H-5i2hA:
21.43
4qw1I-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.23A 4qw1V-5i2hA:
undetectable
4qw1W-5i2hA:
undetectable
4qw1V-5i2hA:
21.43
4qw1W-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 7 ARG A 274
PHE A 319
ASP A 126
TYR A 327
None
1.30A 5a06A-5i2hA:
5.4
5a06A-5i2hA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 7 ARG A 274
PHE A 319
ASP A 126
TYR A 327
None
1.29A 5a06C-5i2hA:
5.3
5a06C-5i2hA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 7 ARG A 274
PHE A 319
ASP A 126
TYR A 327
None
1.30A 5a06D-5i2hA:
5.2
5a06D-5i2hA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 7 ARG A 274
PHE A 319
ASP A 126
TYR A 327
None
1.28A 5a06E-5i2hA:
5.3
5a06E-5i2hA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 7 ARG A 274
PHE A 319
ASP A 126
TYR A 327
None
1.27A 5a06F-5i2hA:
5.3
5a06F-5i2hA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 11 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.21A 5bxnH-5i2hA:
undetectable
5bxnI-5i2hA:
undetectable
5bxnH-5i2hA:
21.70
5bxnI-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.24A 5cz7V-5i2hA:
undetectable
5cz7W-5i2hA:
undetectable
5cz7V-5i2hA:
21.43
5cz7W-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 VAL A  96
LEU A 316
LEU A  76
MET A  74
ALA A  73
None
1.26A 5fctB-5i2hA:
undetectable
5fctB-5i2hA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 GLY A 307
THR A 306
GLY A 202
LEU A 318
None
0.73A 5jlcA-5i2hA:
undetectable
5jlcA-5i2hA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.22A 5l5fH-5i2hA:
undetectable
5l5fI-5i2hA:
undetectable
5l5fH-5i2hA:
21.43
5l5fI-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.22A 5l5fV-5i2hA:
undetectable
5l5fW-5i2hA:
undetectable
5l5fV-5i2hA:
21.43
5l5fW-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.23A 5l66H-5i2hA:
undetectable
5l66I-5i2hA:
undetectable
5l66H-5i2hA:
21.43
5l66I-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 SER A 328
ALA A 312
GLY A 307
THR A 306
THR A  69
None
1.23A 5l66V-5i2hA:
undetectable
5l66W-5i2hA:
undetectable
5l66V-5i2hA:
21.43
5l66W-5i2hA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 ASP A 262
PRO A 258
GLU A 246
ARG A 219
None
1.50A 5uxcA-5i2hA:
1.0
5uxcA-5i2hA:
25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 ALA A 201
GLY A 202
VAL A 228
ASP A 271
TRP A 272
EDO  A 504 ( 3.8A)
None
None
AGI  A 501 (-2.4A)
None
0.76A 5w7pA-5i2hA:
5.8
5w7pA-5i2hA:
27.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 ARG A 293
LEU A 295
PHE A 173
LEU A 177
None
1.02A 5x19C-5i2hA:
undetectable
5x19J-5i2hA:
undetectable
5x19C-5i2hA:
22.46
5x19J-5i2hA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 6 ARG A 293
LEU A 295
PHE A 173
LEU A 177
None
1.02A 5x19P-5i2hA:
undetectable
5x19P-5i2hA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
4 / 5 ARG A 293
LEU A 295
PHE A 173
LEU A 177
None
1.05A 5x1bP-5i2hA:
undetectable
5x1bP-5i2hA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 ALA A 166
GLY A 202
ARG A 225
ASP A 271
TRP A 272
None
None
None
AGI  A 501 (-2.4A)
None
1.30A 6clxA-5i2hA:
22.1
6clxA-5i2hA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 12 ALA A 166
GLY A 203
ARG A 225
ASP A 271
TRP A 272
None
None
None
AGI  A 501 (-2.4A)
None
0.94A 6clxA-5i2hA:
22.1
6clxA-5i2hA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_B_SAMB401_0
(O-METHYLTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 10 ALA A 166
GLY A 202
ASP A 224
ARG A 225
ASP A 271
None
None
EDO  A 504 (-4.0A)
None
AGI  A 501 (-2.4A)
1.01A 6clxB-5i2hA:
22.0
6clxB-5i2hA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_B_SAMB401_0
(O-METHYLTRANSFERASE)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 10 ARG A 165
ALA A 166
GLY A 202
ASP A 224
ARG A 225
AGI  A 501 (-2.8A)
None
None
EDO  A 504 (-4.0A)
None
1.08A 6clxB-5i2hA:
22.0
6clxB-5i2hA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
5 / 11 GLY A 202
ASP A 224
ASP A 251
MET A 252
ASP A 271
None
EDO  A 504 (-4.0A)
EDO  A 504 (-3.8A)
EDO  A 504 (-3.9A)
AGI  A 501 (-2.4A)
0.98A 6i5zD-5i2hA:
16.7
6i5zD-5i2hA:
26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila)
6 / 11 GLY A 203
ASP A 224
VAL A 228
ASP A 251
MET A 252
ASP A 271
None
EDO  A 504 (-4.0A)
None
EDO  A 504 (-3.8A)
EDO  A 504 (-3.9A)
AGI  A 501 (-2.4A)
0.61A 6i5zD-5i2hA:
16.7
6i5zD-5i2hA:
26.90