SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i4d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5i4d SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLU A 262
ILE A 283
LEU A 293
SER A 264
ARG A 276
 None
 1.22A 2e7fB-5i4dA:
undetectable		 2e7fB-5i4dA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5i4d SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLU A 262
ILE A 283
LEU A 293
SER A 264
ARG A 276
 None
 1.21A 2ogyB-5i4dA:
undetectable		 2ogyB-5i4dA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 5i4d SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLU A 235
TYR A 175
VAL A 233
PHE A 295
ASP A 294
 None
 1.47A 2qeoA-5i4dA:
undetectable		 2qeoA-5i4dA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5i4d SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 TYR A 308
GLU A 303
LEU A 297
VAL A 353
ILE A 316
 None
 1.34A 4k39A-5i4dA:
undetectable		 4k39A-5i4dA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5i4d SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ILE A 348
LEU A 290
ILE A 316
ARG A 298
ILE A 351
 None
 1.11A 4x5jA-5i4dA:
undetectable		 4x5jA-5i4dA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5i4d SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLY A 314
TYR A 168
HIS A 305
ARG A 298
LEU A 301
 None
 1.41A 6bp4B-5i4dA:
undetectable		 6bp4B-5i4dA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 5i4d SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		4 / 6 ARG A 197
ILE A 210
MET A 199
ASN A 200
 None
 1.29A 6dhbA-5i4dA:
undetectable		 6dhbA-5i4dA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 5i4d SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		3 / 3 LEU A 301
LEU A 330
ARG A 298
 None
 0.63A 6fgcA-5i4dA:
undetectable		 6fgcA-5i4dA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 5i4d SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		3 / 3 LEU A 301
LEU A 330
ARG A 298
 None
 0.64A 6fgdA-5i4dA:
undetectable		 6fgdA-5i4dA:
21.44