SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 6 TYR A 317
GLY A 316
GLY A 312
TYR A 311
 None
 0.96A 1eswA-5i5dA:
undetectable		 1eswA-5i5dA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 5 PRO A 280
LEU A 282
THR A 293
ARG A 484
 None
 1.21A 1i2wA-5i5dA:
undetectable		 1i2wA-5i5dA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_B_CLWB907_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 5 PRO A 472
VAL A 474
TYR A 272
GLU A 276
 None
 1.21A 1m9jB-5i5dA:
0.0		 1m9jB-5i5dA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 4 HIS A 491
VAL A 494
THR A 266
LEU A 263
 None
 1.01A 1oq5A-5i5dA:
undetectable		 1oq5A-5i5dA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 10 THR A 266
GLY A 450
GLY A 269
ILE A 446
LEU A 473
 None
 1.17A 1x7pA-5i5dA:
undetectable
1x7pB-5i5dA:
undetectable		 1x7pA-5i5dA:
20.77
1x7pB-5i5dA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 10 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.10A 1ydaA-5i5dA:
undetectable		 1ydaA-5i5dA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.10A 1ydbA-5i5dA:
undetectable		 1ydbA-5i5dA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 10 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.06A 1yddA-5i5dA:
undetectable		 1yddA-5i5dA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.05A 1zsbA-5i5dA:
undetectable		 1zsbA-5i5dA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 VAL A 471
GLY A 452
ARG A 451
THR A 302
THR A 402
 None
 1.14A 2f9wA-5i5dA:
1.1
2f9wB-5i5dA:
undetectable		 2f9wA-5i5dA:
19.55
2f9wB-5i5dA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 4 SER A 534
GLY A 533
HIS A 468
ASP A 406
 None
 1.34A 2oxtC-5i5dA:
undetectable		 2oxtC-5i5dA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		3 / 3 ASN A 400
ASN A 403
ARG A 451
 None
 0.91A 2rlcA-5i5dA:
undetectable		 2rlcA-5i5dA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 10 VAL A 471
GLY A 452
ARG A 451
THR A 302
THR A 402
 None
 1.10A 3bexA-5i5dA:
1.2
3bexB-5i5dA:
0.5		 3bexA-5i5dA:
17.32
3bexB-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 9 THR A 402
VAL A 471
GLY A 452
ARG A 451
THR A 302
 None
 1.11A 3bexA-5i5dA:
1.2
3bexB-5i5dA:
0.5		 3bexA-5i5dA:
17.32
3bexB-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 VAL A 471
GLY A 452
ARG A 451
THR A 302
THR A 402
 None
 1.10A 3bexC-5i5dA:
undetectable
3bexD-5i5dA:
undetectable		 3bexC-5i5dA:
17.32
3bexD-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 10 THR A 402
VAL A 471
GLY A 452
ARG A 451
THR A 302
 None
 1.11A 3bexC-5i5dA:
undetectable
3bexD-5i5dA:
undetectable		 3bexC-5i5dA:
17.32
3bexD-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 10 VAL A 471
GLY A 452
ARG A 451
THR A 302
THR A 402
 None
 1.11A 3bexE-5i5dA:
0.9
3bexF-5i5dA:
undetectable		 3bexE-5i5dA:
17.32
3bexF-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 THR A 402
VAL A 471
GLY A 452
ARG A 451
THR A 302
 None
 1.11A 3bexE-5i5dA:
0.9
3bexF-5i5dA:
undetectable		 3bexE-5i5dA:
17.32
3bexF-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 VAL A 471
GLY A 452
ARG A 451
THR A 302
THR A 402
 None
 1.04A 3bf1A-5i5dA:
undetectable
3bf1B-5i5dA:
undetectable		 3bf1A-5i5dA:
17.32
3bf1B-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 THR A 402
VAL A 471
GLY A 452
ARG A 451
THR A 302
 None
 1.06A 3bf1A-5i5dA:
undetectable
3bf1B-5i5dA:
undetectable		 3bf1A-5i5dA:
17.32
3bf1B-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 VAL A 471
GLY A 452
ARG A 451
THR A 302
THR A 402
 None
 1.09A 3bf1C-5i5dA:
1.0
3bf1D-5i5dA:
undetectable		 3bf1C-5i5dA:
17.32
3bf1D-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 THR A 402
VAL A 471
GLY A 452
ARG A 451
THR A 302
 None
 1.08A 3bf1C-5i5dA:
undetectable
3bf1D-5i5dA:
undetectable		 3bf1C-5i5dA:
17.32
3bf1D-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 VAL A 471
GLY A 452
ARG A 451
THR A 302
THR A 402
 None
 1.10A 3bf1E-5i5dA:
1.0
3bf1F-5i5dA:
undetectable		 3bf1E-5i5dA:
17.32
3bf1F-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 THR A 402
VAL A 471
GLY A 452
ARG A 451
THR A 302
 None
 1.13A 3bf1E-5i5dA:
undetectable
3bf1F-5i5dA:
undetectable		 3bf1E-5i5dA:
17.32
3bf1F-5i5dA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.06A 3bl1A-5i5dA:
undetectable		 3bl1A-5i5dA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.09A 3dc3A-5i5dA:
undetectable		 3dc3A-5i5dA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 ALA A 420
LEU A 270
LEU A 282
ILE A 265
LEU A 431
 None
 1.17A 3hj3A-5i5dA:
undetectable		 3hj3A-5i5dA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 ALA A 420
LEU A 270
LEU A 282
ILE A 265
LEU A 431
 None
 1.09A 3hj3B-5i5dA:
undetectable		 3hj3B-5i5dA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 ALA A 420
LEU A 270
LEU A 282
ILE A 265
LEU A 431
 None
 1.10A 3hj3D-5i5dA:
2.4		 3hj3D-5i5dA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.06A 3hs4A-5i5dA:
undetectable		 3hs4A-5i5dA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 8 ARG A 294
ASP A 493
PRO A 541
TRP A 527
 None
 1.24A 3jq7B-5i5dA:
undetectable		 3jq7B-5i5dA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.03A 3kwaA-5i5dA:
undetectable		 3kwaA-5i5dA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		3 / 3 SER A 351
ASP A 303
ASN A 304
 None
 1.02A 3lsfB-5i5dA:
undetectable
3lsfE-5i5dA:
undetectable		 3lsfB-5i5dA:
16.70
3lsfE-5i5dA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		3 / 3 ASP A 303
ASN A 304
SER A 351
 None
 0.95A 3lsfB-5i5dA:
undetectable
3lsfE-5i5dA:
undetectable		 3lsfB-5i5dA:
16.70
3lsfE-5i5dA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.07A 3ml5A-5i5dA:
undetectable		 3ml5A-5i5dA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 7 VAL A 262
ILE A 446
THR A 496
TYR A 512
 None
 1.07A 3tneB-5i5dA:
undetectable		 3tneB-5i5dA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 11 HIS A 491
PHE A 394
VAL A 494
THR A 448
THR A 266
 None
 1.09A 3v2jA-5i5dA:
undetectable		 3v2jA-5i5dA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 TYR A 512
GLN A 500
LEU A 503
LEU A 330
ILE A 446
 None
 1.01A 4g1bD-5i5dA:
undetectable		 4g1bD-5i5dA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 ALA A 420
LEU A 270
LEU A 282
ILE A 265
LEU A 431
 None
 1.11A 4ky8A-5i5dA:
undetectable		 4ky8A-5i5dA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 ALA A 420
LEU A 270
LEU A 282
ILE A 265
LEU A 431
 None
 1.06A 4ky8B-5i5dA:
2.1		 4ky8B-5i5dA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 ALA A 420
LEU A 270
LEU A 282
ILE A 265
LEU A 431
 None
 1.10A 4ky8C-5i5dA:
undetectable		 4ky8C-5i5dA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 ALA A 420
LEU A 270
LEU A 282
ILE A 265
LEU A 431
 None
 1.08A 4ky8D-5i5dA:
undetectable		 4ky8D-5i5dA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		3 / 3 GLN A 575
HIS A 525
ARG A 524
 None
 1.28A 4qyqA-5i5dA:
undetectable		 4qyqA-5i5dA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		3 / 3 GLN A 575
HIS A 525
ARG A 524
 None
 1.21A 4qyqB-5i5dA:
undetectable		 4qyqB-5i5dA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 7 VAL A 444
TRP A 477
ILE A 290
LEU A 309
 None
 1.17A 4xo7B-5i5dA:
undetectable		 4xo7B-5i5dA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 8 ARG A 523
ARG A 524
ASP A 493
ASP A 517
 None
 1.06A 4xqgA-5i5dA:
undetectable		 4xqgA-5i5dA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 8 ARG A 523
ARG A 524
ASP A 493
ASP A 517
 None
 1.08A 4xqgB-5i5dA:
undetectable		 4xqgB-5i5dA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 6 PHE A 583
GLY A 312
TYR A 246
ALA A 329
 None
 1.19A 4yshB-5i5dA:
undetectable		 4yshB-5i5dA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 ASP A 303
ASP A 490
GLY A 312
SER A 513
THR A 496
 None
 1.31A 5hfjE-5i5dA:
undetectable		 5hfjE-5i5dA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		3 / 3 GLY A 308
LEU A 309
HIS A 491
 None
 0.64A 5u63A-5i5dA:
undetectable		 5u63A-5i5dA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		3 / 3 GLY A 308
LEU A 309
HIS A 491
 None
 0.65A 5u63B-5i5dA:
undetectable		 5u63B-5i5dA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 5 THR A 535
ASN A 548
TRP A 464
LEU A 469
 None
 1.25A 5vkqA-5i5dA:
undetectable
5vkqB-5i5dA:
undetectable		 5vkqA-5i5dA:
16.78
5vkqB-5i5dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		4 / 7 LEU A 503
GLN A 500
LEU A 334
PHE A 394
 None
 0.94A 5zcoC-5i5dA:
undetectable
5zcoJ-5i5dA:
undetectable		 5zcoC-5i5dA:
19.11
5zcoJ-5i5dA:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 GLY A 312
VAL A 321
ILE A 538
SER A 298
ALA A 531
 None
 1.13A 6c2mA-5i5dA:
undetectable		 6c2mA-5i5dA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 5i5d INNER MEMBRANE
PROTEIN YEJM
(Salmonella
enterica) 		5 / 12 GLY A 312
VAL A 321
ILE A 538
SER A 298
ALA A 531
 None
 1.07A 6c2mB-5i5dA:
undetectable		 6c2mB-5i5dA:
10.33