SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i5l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ILE A 433
LEU A 484
LEU A 402
GLY A 418
PHE A 435
 None
 1.10A 1axwA-5i5lA:
undetectable		 1axwA-5i5lA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 4 ARG A 292
ALA A 290
ALA A 117
GLU A 115
 None
 1.08A 1e7bA-5i5lA:
undetectable		 1e7bA-5i5lA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 4 ARG A 292
ALA A 290
ALA A 117
GLU A 115
 None
 1.04A 1e7bB-5i5lA:
1.7		 1e7bB-5i5lA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 ARG A 244
PRO A 215
SER A 286
MET A 263
 BLA  A 601 (-3.0A)
None
None
None
 1.04A 2qd2A-5i5lA:
undetectable		 2qd2A-5i5lA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 6 ARG A 244
PRO A 215
SER A 286
MET A 263
 BLA  A 601 (-3.0A)
None
None
None
 1.02A 2qd3B-5i5lA:
undetectable		 2qd3B-5i5lA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 ASP A 197
TYR A 166
GLY A 174
PRO A 194
 BLA  A 601 (-4.1A)
BLA  A 601 ( 4.2A)
None
None
 0.99A 2ys6A-5i5lA:
undetectable		 2ys6A-5i5lA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 LEU A  62
LEU A  54
ILE A  76
SER A  51
VAL A 101
 None
 1.25A 3aqiB-5i5lA:
undetectable		 3aqiB-5i5lA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 11 ALA A  68
LEU A  62
ILE A  64
PRO A  63
GLY A  65
 None
 1.45A 3bpxA-5i5lA:
undetectable
3bpxB-5i5lA:
undetectable		 3bpxA-5i5lA:
15.12
3bpxB-5i5lA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 4 ILE A 111
GLN A 242
ILE A 224
LEU A 211
 None
 1.04A 3dzyD-5i5lA:
undetectable		 3dzyD-5i5lA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 ARG A 244
PRO A 215
SER A 286
MET A 263
 BLA  A 601 (-3.0A)
None
None
None
 1.04A 3hcrA-5i5lA:
undetectable		 3hcrA-5i5lA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 7 ARG A 244
PRO A 215
SER A 286
MET A 263
 BLA  A 601 (-3.0A)
None
None
None
 1.05A 3hcrB-5i5lA:
undetectable		 3hcrB-5i5lA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 7 LEU A  79
LEU A  40
SER A 106
THR A 232
 None
 1.06A 3lm8B-5i5lA:
undetectable
3lm8D-5i5lA:
undetectable		 3lm8B-5i5lA:
18.22
3lm8D-5i5lA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 GLY A 341
GLY A 344
ALA A 334
ALA A 333
LEU A 352
 None
 0.98A 3p2kA-5i5lA:
undetectable		 3p2kA-5i5lA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 GLY A 341
GLY A 344
ALA A 334
ALA A 333
LEU A 352
 None
 0.97A 3p2kC-5i5lA:
undetectable		 3p2kC-5i5lA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 GLY A 341
GLY A 344
ALA A 334
ALA A 333
LEU A 352
 None
 0.91A 3p2kD-5i5lA:
undetectable		 3p2kD-5i5lA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 5 SER A 464
PRO A 461
TYR A 253
VAL A 453
 None
BLA  A 601 ( 4.6A)
BLA  A 601 (-4.4A)
None
 1.28A 3sufC-5i5lA:
undetectable		 3sufC-5i5lA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 LEU A  62
LEU A  54
ILE A  76
SER A  51
VAL A 101
 None
 1.22A 3w1wA-5i5lA:
undetectable		 3w1wA-5i5lA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ILE A 433
LEU A 484
LEU A 402
GLY A 418
PHE A 435
 None
 1.23A 4foxB-5i5lA:
undetectable		 4foxB-5i5lA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 7 ARG A 244
PRO A 215
SER A 286
MET A 263
 BLA  A 601 (-3.0A)
None
None
None
 1.03A 4klrA-5i5lA:
undetectable		 4klrA-5i5lA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ILE A 224
PRO A 223
ILE A  31
SER A 241
ARG A 225
 None
 1.16A 4uroA-5i5lA:
undetectable		 4uroA-5i5lA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ILE A 224
PRO A 223
ILE A  31
SER A 241
ARG A 225
 None
 1.11A 4uroB-5i5lA:
undetectable		 4uroB-5i5lA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ILE A 224
PRO A 223
ILE A  31
SER A 241
ARG A 225
 None
 1.13A 4uroC-5i5lA:
undetectable		 4uroC-5i5lA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ILE A 224
PRO A 223
ILE A  31
SER A 241
ARG A 225
 None
 1.17A 4uroD-5i5lA:
undetectable		 4uroD-5i5lA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_F_EVPF102_1
(DNA TOPOISOMERASE
2-ALPHA)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 5 GLY A 169
ASP A 171
ARG A 192
MET A 257
 CA  A 602 ( 4.3A)
None
None
BLA  A 601 ( 3.7A)
 1.35A 5gwkA-5i5lA:
undetectable		 5gwkA-5i5lA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 7 GLY A 357
ALA A 358
ASP A 359
GLY A 418
 None
 0.65A 5kqyB-5i5lA:
undetectable		 5kqyB-5i5lA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 GLY A 357
ALA A 358
ASP A 359
GLY A 418
 None
 0.58A 5kr1B-5i5lA:
undetectable		 5kr1B-5i5lA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAC_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 GLN A  32
HIS A  34
SER A 262
ARG A 255
PRO A 284
 None
None
BLA  A 601 (-3.0A)
None
None
 1.38A 5uacC-5i5lA:
2.0		 5uacC-5i5lA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		3 / 3 GLY A  35
THR A 283
PRO A 215
 None
 0.62A 5v5zA-5i5lA:
undetectable		 5v5zA-5i5lA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 GLU A  96
LEU A  40
LEU A  79
LEU A 112
GLY A  59
 None
 0.97A 6b0cD-5i5lA:
undetectable		 6b0cD-5i5lA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 9 VAL A 381
VAL A 415
LEU A 384
GLY A 418
LEU A 402
 None
 1.19A 6czmA-5i5lA:
undetectable
6czmB-5i5lA:
undetectable		 6czmA-5i5lA:
22.01
6czmB-5i5lA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 9 VAL A 381
VAL A 415
LEU A 384
GLY A 418
LEU A 402
 None
 1.18A 6czmB-5i5lA:
undetectable
6czmC-5i5lA:
undetectable		 6czmB-5i5lA:
22.01
6czmC-5i5lA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 9 VAL A 381
VAL A 415
LEU A 384
GLY A 418
LEU A 402
 None
 1.16A 6czmD-5i5lA:
undetectable
6czmE-5i5lA:
undetectable		 6czmD-5i5lA:
22.01
6czmE-5i5lA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		5 / 10 VAL A 381
VAL A 415
LEU A 384
GLY A 418
LEU A 402
 None
 1.19A 6czmE-5i5lA:
undetectable
6czmF-5i5lA:
undetectable		 6czmE-5i5lA:
22.01
6czmF-5i5lA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 5i5l BACTERIOPHYTOCHROME
PROTEIN
(Agrobacterium
fabrum) 		6 / 12 PRO A 376
ILE A 433
LEU A 484
LEU A 402
GLY A 418
PHE A 435
 None
 1.45A 6qxsB-5i5lA:
undetectable		 6qxsB-5i5lA:
23.03