SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i6h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 VAL A1840
GLY A1839
LEU A1767
VAL A1629
PHE A1553
None
1.47A 1a27A-5i6hA:
undetectable
1a27A-5i6hA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 7 LEU A1328
THR A1087
ASN A1256
TYR A1105
None
1.38A 1afsA-5i6hA:
undetectable
1afsA-5i6hA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 7 LEU A1328
THR A1087
ASN A1256
TYR A1105
None
1.37A 1afsB-5i6hA:
undetectable
1afsB-5i6hA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A 915
GLY A 917
ALA A 920
ASN A 924
SER A 909
None
1.15A 1dfoA-5i6hA:
undetectable
1dfoA-5i6hA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A 915
GLY A 917
ALA A 920
ASN A 924
SER A 909
None
1.14A 1dfoB-5i6hA:
undetectable
1dfoB-5i6hA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A 915
GLY A 917
ALA A 920
ASN A 924
SER A 909
None
1.15A 1dfoC-5i6hA:
undetectable
1dfoC-5i6hA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A 915
GLY A 917
ALA A 920
ASN A 924
SER A 909
None
1.14A 1dfoD-5i6hA:
undetectable
1dfoD-5i6hA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 6 GLN A1454
ARG A1367
TYR A1525
PHE A1340
None
1.32A 1e73M-5i6hA:
undetectable
1e73M-5i6hA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 8 LEU A1991
ALA A1934
VAL A1919
TYR A1874
None
0.75A 1epbB-5i6hA:
undetectable
1epbB-5i6hA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A 915
GLY A 917
ALA A 920
ASN A 924
SER A 909
None
1.11A 1eqbA-5i6hA:
undetectable
1eqbA-5i6hA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A 915
GLY A 917
ALA A 920
ASN A 924
SER A 909
None
1.11A 1eqbB-5i6hA:
undetectable
1eqbB-5i6hA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A 915
GLY A 917
ALA A 920
ASN A 924
SER A 909
None
1.11A 1eqbC-5i6hA:
undetectable
1eqbC-5i6hA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A 915
GLY A 917
ALA A 920
ASN A 924
SER A 909
None
1.11A 1eqbD-5i6hA:
undetectable
1eqbD-5i6hA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 7 MET A1609
SER A1772
PHE A1641
ALA A1668
None
1.23A 1fxvA-5i6hA:
undetectable
1fxvB-5i6hA:
undetectable
1fxvA-5i6hA:
9.26
1fxvB-5i6hA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 8 SER A1281
ILE A1274
PHE A1295
VAL A1255
None
1.09A 1kb9A-5i6hA:
undetectable
1kb9C-5i6hA:
undetectable
1kb9D-5i6hA:
undetectable
1kb9E-5i6hA:
undetectable
1kb9A-5i6hA:
15.17
1kb9C-5i6hA:
13.32
1kb9D-5i6hA:
10.22
1kb9E-5i6hA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 9 GLY A2064
LEU A2066
GLU A2067
ARG A1995
GLY A2038
None
1.24A 1l5kA-5i6hA:
1.7
1l5kA-5i6hA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 9 GLY A2064
LEU A2066
GLU A2067
ARG A1995
GLY A2038
None
1.20A 1l5mA-5i6hA:
3.2
1l5mA-5i6hA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 8 GLY A2012
SER A1969
THR A1917
ASP A2003
None
0.90A 1m4iA-5i6hA:
undetectable
1m4iA-5i6hA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 ILE A1664
PHE A1627
LYS A1626
SER A1560
ILE A1557
None
1.28A 1rh3A-5i6hA:
undetectable
1rh3A-5i6hA:
7.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 GLY A2038
GLY A2039
ILE A2150
GLY A2148
PRO A2046
None
1.03A 1sqfA-5i6hA:
undetectable
1sqfA-5i6hA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 7 LEU A1901
GLY A1900
LEU A1991
PRO A1876
None
0.93A 1ya4B-5i6hA:
undetectable
1ya4B-5i6hA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 ASP A1646
GLY A1671
ALA A1752
ILE A1751
None
0.85A 2aofA-5i6hA:
undetectable
2aofA-5i6hA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 TYR A1982
ASN A1981
ASP A1761
ALA A1758
ALA A1754
None
1.09A 2br4B-5i6hA:
undetectable
2br4B-5i6hA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 7 ASP A1068
PRO A1067
SER A1050
LEU A1086
None
1.04A 2hdnE-5i6hA:
undetectable
2hdnF-5i6hA:
3.3
2hdnH-5i6hA:
3.3
2hdnE-5i6hA:
2.97
2hdnF-5i6hA:
13.01
2hdnH-5i6hA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 LEU A 986
ALA A 984
LEU A 981
MET A 932
None
1.21A 2oaxA-5i6hA:
undetectable
2oaxA-5i6hA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
3 / 3 GLY A1913
ARG A1916
TYR A1824
None
0.56A 2opxA-5i6hA:
undetectable
2opxA-5i6hA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 GLU A2054
ARG A2166
ILE A2150
GLU A2204
ASP A2226
None
1.01A 2qeoA-5i6hA:
undetectable
2qeoA-5i6hA:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_B_LNRB200_1
(D7R4 PROTEIN)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 10 GLU A2054
ARG A2166
ILE A2150
GLU A2204
ASP A2226
None
0.96A 2qeoB-5i6hA:
undetectable
2qeoB-5i6hA:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 GLU A2069
PRO A2068
ILE A2071
GLY A2070
None
1.08A 2qeuA-5i6hA:
undetectable
2qeuC-5i6hA:
undetectable
2qeuA-5i6hA:
7.65
2qeuC-5i6hA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 ILE A1321
ARG A1292
ARG A1311
ASP A1318
None
1.40A 2rhmB-5i6hA:
undetectable
2rhmB-5i6hA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 ILE A1321
ARG A1292
ARG A1311
ASP A1318
None
1.39A 2rhmD-5i6hA:
0.9
2rhmD-5i6hA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W13_A_ACTA1208_0
(ZINC
METALLOPROTEINASE
BAP1)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 4 THR A1917
ARG A1916
GLU A1960
ASN A1942
None
1.46A 2w13A-5i6hA:
undetectable
2w13A-5i6hA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 ILE A1850
PHE A1980
PRO A1929
PHE A1907
None
1.28A 2ygnA-5i6hA:
undetectable
2ygnA-5i6hA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 7 GLU A1501
ARG A1167
GLU A1162
SER A1522
None
1.08A 2zt7A-5i6hA:
undetectable
2zt7A-5i6hA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
3 / 3 THR A1087
SER A1306
LYS A1350
None
1.04A 3aocC-5i6hA:
undetectable
3aocC-5i6hA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 11 LEU A1782
PHE A1649
ILE A1775
GLY A1776
SER A1667
None
1.44A 3bpxA-5i6hA:
undetectable
3bpxB-5i6hA:
undetectable
3bpxA-5i6hA:
7.68
3bpxB-5i6hA:
7.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 4 VAL A1546
ARG A1663
ILE A1614
THR A1769
None
1.37A 3cl9A-5i6hA:
undetectable
3cl9A-5i6hA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 ALA A2018
SER A2052
PRO A2050
ASN A2196
TYR A1982
None
1.42A 3eigA-5i6hA:
undetectable
3eigA-5i6hA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 8 ALA A1758
ASP A1761
ILE A1628
THR A1766
None
0.85A 3el9A-5i6hA:
undetectable
3el9A-5i6hA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 ILE A1664
PHE A1627
LYS A1626
SER A1560
ILE A1557
None
1.11A 3ia4D-5i6hA:
undetectable
3ia4D-5i6hA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 ASN A1968
TRP A1965
PRO A2031
GLY A1963
ILE A1940
None
1.28A 3iv6A-5i6hA:
undetectable
3iv6A-5i6hA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 ASN A 967
MET A 932
VAL A 818
ILE A 810
ASN A 974
None
1.44A 3jayA-5i6hA:
2.4
3jayA-5i6hA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 ASN A 967
MET A 932
VAL A 818
ILE A 810
ASN A 974
None
1.37A 3jb2A-5i6hA:
undetectable
3jb2A-5i6hA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 7 TYR A1113
TYR A1110
TYR A1105
PHE A1083
None
1.26A 3ku9B-5i6hA:
1.2
3ku9B-5i6hA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
3 / 3 LYS A1644
ARG A1673
LYS A1534
None
1.42A 3okxA-5i6hA:
undetectable
3okxA-5i6hA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
3 / 3 ASN A1510
ALA A1511
LYS A1512
None
1.00A 3runA-5i6hA:
undetectable
3runA-5i6hA:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A1436
VAL A1432
ILE A1457
HIS A1416
TYR A1525
None
1.21A 3sp9A-5i6hA:
undetectable
3sp9A-5i6hA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 7 PHE A1641
PHE A1649
ALA A1752
THR A1755
None
0.99A 3t3sC-5i6hA:
undetectable
3t3sC-5i6hA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 8 PHE A1641
PHE A1649
ALA A1752
THR A1755
None
0.92A 3t3sE-5i6hA:
undetectable
3t3sE-5i6hA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 ILE A1928
PRO A1929
SER A1862
GLY A1927
None
1.09A 3tkdB-5i6hA:
undetectable
3tkdB-5i6hA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 ILE A1928
PRO A1929
SER A1862
GLY A1927
None
1.11A 3tkdA-5i6hA:
undetectable
3tkdA-5i6hA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 TRP A1994
VAL A1935
ILE A1990
LEU A1901
VAL A1872
None
1.02A 3w68D-5i6hA:
3.5
3w68D-5i6hA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
3 / 3 ARG A1663
ASP A1979
GLN A1975
None
0.79A 4azsA-5i6hA:
undetectable
4azsA-5i6hA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 11 SER A1667
VAL A1787
LEU A1767
GLU A1790
ALA A1833
None
1.06A 4e0fA-5i6hA:
undetectable
4e0fA-5i6hA:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 TYR A1096
LEU A1099
LEU A1072
ARG A1107
None
1.48A 4em2A-5i6hA:
undetectable
4em2A-5i6hA:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 GLY A1912
GLY A1913
TYR A1824
VAL A1935
ILE A1940
None
1.21A 4fglA-5i6hA:
3.0
4fglB-5i6hA:
3.1
4fglA-5i6hA:
10.94
4fglB-5i6hA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
3 / 3 TYR A1504
PHE A1418
ARG A1336
None
1.16A 4g19D-5i6hA:
undetectable
4g19D-5i6hA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 LEU A1541
SER A1667
PHE A1641
LEU A1674
VAL A1773
None
1.25A 4ib4A-5i6hA:
undetectable
4ib4A-5i6hA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 GLU A2054
ARG A2166
PRO A2203
SER A2202
None
1.43A 4k17B-5i6hA:
3.1
4k17B-5i6hA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 11 ILE A1664
PHE A1627
LYS A1626
SER A1560
ILE A1557
None
1.33A 4p68A-5i6hA:
undetectable
4p68A-5i6hA:
7.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 8 LEU A1204
VAL A1255
VAL A1192
LEU A1285
None
1.10A 4pwdC-5i6hA:
undetectable
4pwdC-5i6hA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 8 PHE A1649
GLY A1776
ASN A1632
ILE A1794
None
1.00A 4qoiA-5i6hA:
2.9
4qoiB-5i6hA:
undetectable
4qoiA-5i6hA:
10.87
4qoiB-5i6hA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 TYR A1127
PRO A1126
LEU A1102
TYR A1120
None
1.20A 4w5qA-5i6hA:
2.4
4w5qA-5i6hA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 6 LEU A 986
ASP A 987
TYR A 933
LEU A 930
None
0.98A 4wozA-5i6hA:
2.6
4wozB-5i6hA:
undetectable
4wozA-5i6hA:
12.23
4wozB-5i6hA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
3 / 3 MET A1174
ASP A1164
PHE A1165
None
1.04A 4xeyB-5i6hA:
1.2
4xeyB-5i6hA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 SER A1772
PHE A1641
PHE A1649
ILE A1775
VAL A1780
None
1.31A 4yfbC-5i6hA:
undetectable
4yfbC-5i6hA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 SER A1772
PHE A1641
PHE A1649
ILE A1775
VAL A1780
None
1.31A 4yfbF-5i6hA:
undetectable
4yfbF-5i6hA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 SER A1772
PHE A1641
PHE A1649
ILE A1775
VAL A1780
None
1.30A 4yfbI-5i6hA:
undetectable
4yfbI-5i6hA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 SER A1772
PHE A1641
PHE A1649
ILE A1775
VAL A1780
None
1.30A 4yfbL-5i6hA:
undetectable
4yfbL-5i6hA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 6 TYR A1127
PRO A1126
LEU A1102
TYR A1120
None
1.18A 4z4cA-5i6hA:
undetectable
4z4cA-5i6hA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 5 VAL A1190
TYR A1304
ILE A1352
PRO A1326
None
1.32A 4ze1A-5i6hA:
undetectable
4ze1A-5i6hA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
3 / 3 TRP A1846
ARG A1785
LEU A1911
None
0.93A 5dbyA-5i6hA:
undetectable
5dbyA-5i6hA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 11 ILE A1664
ILE A1843
VAL A1629
ASP A1836
ALA A1556
None
0.97A 5lg3A-5i6hA:
undetectable
5lg3A-5i6hA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 12 ILE A1664
ILE A1843
VAL A1629
ASP A1836
ALA A1556
None
1.06A 5lg3E-5i6hA:
undetectable
5lg3E-5i6hA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
3 / 3 SER A1170
SER A1172
PHE A1133
None
0.93A 5mugA-5i6hA:
2.3
5mugA-5i6hA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 7 GLY A1926
SER A1906
ARG A2227
ASP A1866
None
1.09A 5n5dB-5i6hA:
undetectable
5n5dB-5i6hA:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 6 ALA A1777
LEU A1779
TYR A1665
SER A1772
None
1.10A 5phhA-5i6hA:
undetectable
5phhA-5i6hA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEO_A_CYZA1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 10 PRO A1859
ILE A1928
PRO A1929
SER A1862
GLY A1927
None
1.17A 5weoA-5i6hA:
2.3
5weoD-5i6hA:
undetectable
5weoA-5i6hA:
21.26
5weoD-5i6hA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEO_B_CYZB1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 9 PRO A1859
ILE A1928
PRO A1929
SER A1862
GLY A1927
None
1.16A 5weoB-5i6hA:
undetectable
5weoC-5i6hA:
2.3
5weoB-5i6hA:
21.26
5weoC-5i6hA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEO_D_CYZD1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 9 ILE A1928
PRO A1929
SER A1862
GLY A1927
PRO A1859
None
1.16A 5weoA-5i6hA:
2.3
5weoD-5i6hA:
undetectable
5weoA-5i6hA:
21.26
5weoD-5i6hA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 11 VAL A1920
GLY A1921
ASP A1979
ALA A1976
LEU A1911
None
0.92A 5x6yA-5i6hA:
3.1
5x6yA-5i6hA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 8 GLY A2070
ILE A2072
ASP A2139
ASP A2136
HIS A2138
None
1.28A 6ag0A-5i6hA:
undetectable
6ag0A-5i6hA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
5 / 8 GLY A2070
ILE A2072
ASP A2139
ASP A2136
HIS A2138
None
1.26A 6ag0C-5i6hA:
undetectable
6ag0C-5i6hA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum)
4 / 6 ARG A1870
PHE A2162
LEU A1901
PHE A1902
None
1.07A 6nmpC-5i6hA:
undetectable
6nmpJ-5i6hA:
undetectable
6nmpC-5i6hA:
9.27
6nmpJ-5i6hA:
3.45