SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i6i'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A27_A_ESTA350_1 (17-BETA-HYDROXYSTERO ID-DEHYDROGENASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	VAL A1840 GLY A1839 LEU A1767 VAL A1629 PHE A1553	None	1.41A	1a27A-5i6iA: 2.9	1a27A-5i6iA: 9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EPB_B_9CRB165_2 (EPIDIDYMAL RETINOIC ACID-BINDING PROTEIN)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 8	LEU A1991 ALA A1934 VAL A1919 TYR A1874	None	0.72A	1epbB-5i6iA: 2.4	1epbB-5i6iA: 5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHO_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	GLY A2064 LEU A2066 GLU A2067 ARG A1995 GLY A2038	None	1.27A	1jhoA-5i6iA: 3.0	1jhoA-5i6iA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHR_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	GLY A2064 LEU A2066 GLU A2067 ARG A1995 GLY A2038	None	1.26A	1jhrA-5i6iA: undetectable	1jhrA-5i6iA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHY_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	GLY A2064 LEU A2066 GLU A2067 ARG A1995 GLY A2038	None	1.25A	1jhyA-5i6iA: 2.2	1jhyA-5i6iA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L4N_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	GLY A2064 LEU A2066 GLU A2067 ARG A1995 GLY A2038	None	1.20A	1l4nA-5i6iA: 2.7	1l4nA-5i6iA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5K_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	GLY A2064 LEU A2066 GLU A2067 ARG A1995 GLY A2038	None	1.25A	1l5kA-5i6iA: 1.9	1l5kA-5i6iA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5L_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	GLY A2064 LEU A2066 GLU A2067 ARG A1995 GLY A2038	None	1.23A	1l5lA-5i6iA: 2.5	1l5lA-5i6iA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5M_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	GLY A2064 LEU A2066 GLU A2067 ARG A1995 GLY A2038	None	1.21A	1l5mA-5i6iA: undetectable	1l5mA-5i6iA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_A_SAMA301_0 (HEMK PROTEIN)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	ILE A1419 ILE A1352 SER A1391 ASN A1351 PRO A1376	None	1.15A	1sg9A-5i6iA: 4.3	1sg9A-5i6iA: 8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQF_A_SAMA430_0 (SUN PROTEIN)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	GLY A2038 GLY A2039 ILE A2150 GLY A2148 PRO A2046	None	1.04A	1sqfA-5i6iA: undetectable	1sqfA-5i6iA: 11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_F_9CRF1600_2 (RETINOIC ACID RECEPTOR, BETA)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	3 / 3	LEU A1988 PHE A1980 ARG A1885	None	0.84A	1xdkF-5i6iA: undetectable	1xdkF-5i6iA: 9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_B_CTXB1283_1 (CES1 PROTEIN)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	LEU A1901 GLY A1900 LEU A1991 PRO A1876	None	0.93A	1ya4B-5i6iA: 2.4	1ya4B-5i6iA: 13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	3 / 3	TRP A1131 ARG A1187 PHE A1133	None	1.41A	1zeaH-5i6iA: undetectable 1zeaL-5i6iA: undetectable	1zeaH-5i6iA: 7.49 1zeaL-5i6iA: 7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOF_C_FRDC305_1 (POL POLYPROTEIN PEPTIDE INHIBITOR)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ASP A1646 GLY A1671 ALA A1752 ILE A1751	None	0.84A	2aofA-5i6iA: undetectable	2aofA-5i6iA: 4.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_B_SAMB301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	TYR A1982 ASN A1981 ASP A1761 ALA A1758 ALA A1754	None	1.01A	2br4B-5i6iA: undetectable	2br4B-5i6iA: 8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OPX_A_DXCA1002_0 (ALDEHYDE DEHYDROGENASE A)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	3 / 3	GLY A1913 ARG A1916 TYR A1824	None	0.59A	2opxA-5i6iA: undetectable	2opxA-5i6iA: 13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEO_A_LNRA200_1 (D7R4 PROTEIN)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	GLU A2054 ARG A2166 ILE A2150 GLU A2204 ASP A2226	None	1.09A	2qeoA-5i6iA: undetectable	2qeoA-5i6iA: 5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEO_B_LNRB200_1 (D7R4 PROTEIN)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 10	GLU A2054 ARG A2166 ILE A2150 GLU A2204 ASP A2226	None	1.04A	2qeoB-5i6iA: undetectable	2qeoB-5i6iA: 5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEU_A_ACTA142_0 (PUTATIVE CARBOXYMUCONOLACTONE DECARBOXYLASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	GLU A2069 PRO A2068 ILE A2071 GLY A2070	None	1.11A	2qeuA-5i6iA: undetectable 2qeuC-5i6iA: 3.1	2qeuA-5i6iA: 5.20 2qeuC-5i6iA: 5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RHM_B_BEZB194_0 (PUTATIVE KINASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ILE A1321 ARG A1292 ARG A1311 ASP A1318	None	1.39A	2rhmB-5i6iA: 2.0	2rhmB-5i6iA: 6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RHM_D_BEZD194_0 (PUTATIVE KINASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ILE A1321 ARG A1292 ARG A1311 ASP A1318	None	1.44A	2rhmD-5i6iA: undetectable	2rhmD-5i6iA: 6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V41_G_BEZG1222_0 (PEROXIREDOXIN 6.)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 8	THR A1087 VAL A1259 ALA A1262 PRO A1305	None	1.08A	2v41G-5i6iA: undetectable 2v41H-5i6iA: undetectable	2v41G-5i6iA: 7.19 2v41H-5i6iA: 7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_PCFA1179_1 (WNT INHIBITORY FACTOR 1)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ILE A1850 PHE A1980 PRO A1929 PHE A1907	None	1.21A	2ygnA-5i6iA: undetectable	2ygnA-5i6iA: 5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BPX_B_SALB258_1 (TRANSCRIPTIONAL REGULATOR)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	LEU A1782 PHE A1649 ILE A1775 GLY A1776 SER A1667	None	1.42A	3bpxA-5i6iA: undetectable 3bpxB-5i6iA: undetectable	3bpxA-5i6iA: 5.25 3bpxB-5i6iA: 5.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CL9_A_MTXA602_2 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE (DHFR-TS))	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 4	VAL A1546 ARG A1663 ILE A1614 THR A1769	None	1.27A	3cl9A-5i6iA: undetectable	3cl9A-5i6iA: 12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_D_MTXD164_1 (DIHYDROFOLATE REDUCTASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	ILE A1664 PHE A1627 LYS A1626 SER A1560 ILE A1557	None	1.20A	3ia4D-5i6iA: undetectable	3ia4D-5i6iA: 5.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_A_SAMA301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	ASN A1968 TRP A1965 PRO A2031 GLY A1963 ILE A1940	None	1.26A	3iv6A-5i6iA: undetectable	3iv6A-5i6iA: 8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A1436 VAL A1432 ILE A1457 HIS A1416 TYR A1525	None	1.22A	3sp9A-5i6iA: undetectable	3sp9A-5i6iA: 8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_C_9PLC1_1 (CYTOCHROME P450 2A13)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	PHE A1641 PHE A1649 ALA A1752 THR A1755	None	0.96A	3t3sC-5i6iA: undetectable	3t3sC-5i6iA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_E_9PLE1_1 (CYTOCHROME P450 2A13)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 8	PHE A1641 PHE A1649 ALA A1752 THR A1755	None	0.88A	3t3sE-5i6iA: undetectable	3t3sE-5i6iA: 12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZS_A_SAMA1475_1 (METHYLTRANSFERASE WBDD)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	3 / 3	ARG A1663 ASP A1979 GLN A1975	None	0.86A	4azsA-5i6iA: undetectable	4azsA-5i6iA: 13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E0F_A_RBFA301_1 (RIBOFLAVIN SYNTHASE SUBUNIT ALPHA)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	SER A1667 VAL A1787 LEU A1767 GLU A1790 ALA A1833	None	0.98A	4e0fA-5i6iA: undetectable	4e0fA-5i6iA: 6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 8	GLY A1931 VAL A1932 PHE A2022 ILE A2026	None	0.92A	4fglD-5i6iA: undetectable	4fglD-5i6iA: 7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G19_D_ACTD302_0 (GLUTATHIONE TRANSFERASE GTE1)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	3 / 3	TYR A1504 PHE A1418 ARG A1336	None	1.18A	4g19D-5i6iA: undetectable	4g19D-5i6iA: 7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K17_B_OHBB701_0 (LEUCINE-RICH REPEAT-CONTAINING PROTEIN 16A)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	GLU A2054 ARG A2166 PRO A2203 SER A2202	None	1.42A	4k17B-5i6iA: 2.9	4k17B-5i6iA: 15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KQI_A_NIOA403_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	GLY A2064 LEU A2066 GLU A2067 ARG A1995 GLY A2038	None	1.25A	4kqiA-5i6iA: 2.9	4kqiA-5i6iA: 10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_C_AERC601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ASP A2058 GLU A2035 VAL A1935 ALA A1934	None	1.17A	4nkvC-5i6iA: undetectable	4nkvC-5i6iA: 13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PWD_C_NVPC901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 8	LEU A1204 VAL A1255 VAL A1192 LEU A1285	None	1.07A	4pwdC-5i6iA: undetectable	4pwdC-5i6iA: 14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5Q_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	TYR A1127 PRO A1126 LEU A1102 TYR A1120	None	1.27A	4w5qA-5i6iA: 2.4	4w5qA-5i6iA: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WOZ_B_MN9B401_0 (N-ACETYLNEURAMINATE LYASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	LEU A 986 ASP A 987 TYR A 933 LEU A 930	None	0.98A	4wozA-5i6iA: undetectable 4wozB-5i6iA: undetectable	4wozA-5i6iA: 9.38 4wozB-5i6iA: 9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YFB_C_PACC601_0 (PROTEIN RELATED TO PENICILLIN ACYLASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	SER A1772 PHE A1641 PHE A1649 ILE A1775 VAL A1780	None	1.21A	4yfbC-5i6iA: undetectable	4yfbC-5i6iA: 13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YFB_F_PACF601_0 (PROTEIN RELATED TO PENICILLIN ACYLASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	SER A1772 PHE A1641 PHE A1649 ILE A1775 VAL A1780	None	1.21A	4yfbF-5i6iA: undetectable	4yfbF-5i6iA: 13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YFB_I_PACI601_0 (PROTEIN RELATED TO PENICILLIN ACYLASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	SER A1772 PHE A1641 PHE A1649 ILE A1775 VAL A1780	None	1.20A	4yfbI-5i6iA: undetectable	4yfbI-5i6iA: 13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YFB_L_PACL601_0 (PROTEIN RELATED TO PENICILLIN ACYLASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	SER A1772 PHE A1641 PHE A1649 ILE A1775 VAL A1780	None	1.20A	4yfbL-5i6iA: undetectable	4yfbL-5i6iA: 13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	TYR A1127 PRO A1126 LEU A1102 TYR A1120	None	1.27A	4z4cA-5i6iA: 2.4	4z4cA-5i6iA: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DBY_A_ACTA617_0 (SERUM ALBUMIN)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	3 / 3	TRP A1846 ARG A1785 LEU A1911	None	0.98A	5dbyA-5i6iA: undetectable	5dbyA-5i6iA: 14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	LEU A 879 PHE A 883 LEU A 860 PHE A 845	None	1.25A	5iy5P-5i6iA: undetectable 5iy5W-5i6iA: undetectable	5iy5P-5i6iA: 7.96 5iy5W-5i6iA: 2.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_A_Z80A401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	ILE A1664 ILE A1843 VAL A1629 ASP A1836 ALA A1556	None	1.06A	5lg3A-5i6iA: undetectable	5lg3A-5i6iA: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N5D_B_SAMB303_1 (METHYLTRANSFERASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	GLY A1926 SER A1906 ARG A2227 ASP A1866	None	0.99A	5n5dB-5i6iA: undetectable	5n5dB-5i6iA: 6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5PHH_A_LDPA414_1 (LYSINE-SPECIFIC DEMETHYLASE 4D)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ALA A1777 LEU A1779 TYR A1665 SER A1772	None	1.10A	5phhA-5i6iA: undetectable	5phhA-5i6iA: 9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WEO_A_CYZA1302_1 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT CHIMERA)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 10	PRO A1859 ILE A1928 PRO A1929 SER A1862 GLY A1927	None	1.30A	5weoA-5i6iA: undetectable 5weoD-5i6iA: undetectable	5weoA-5i6iA: 19.12 5weoD-5i6iA: 19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WEO_B_CYZB1302_1 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT CHIMERA)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	PRO A1859 ILE A1928 PRO A1929 SER A1862 GLY A1927	None	1.30A	5weoB-5i6iA: undetectable 5weoC-5i6iA: undetectable	5weoB-5i6iA: 19.12 5weoC-5i6iA: 19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WEO_D_CYZD1302_1 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT CHIMERA)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 9	ILE A1928 PRO A1929 SER A1862 GLY A1927 PRO A1859	None	1.29A	5weoA-5i6iA: undetectable 5weoD-5i6iA: undetectable	5weoA-5i6iA: 19.12 5weoD-5i6iA: 19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_A_SAMA901_0 (MRNA CAPPING ENZYME P5)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	VAL A1920 GLY A1921 ASP A1979 ALA A1976 LEU A1911	None	0.95A	5x6yA-5i6iA: 2.7	5x6yA-5i6iA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_B_SAMB901_0 (MRNA CAPPING ENZYME P5)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 10	VAL A1920 GLY A1921 ASP A1979 ALA A1976 LEU A1911	None	0.98A	5x6yB-5i6iA: undetectable	5x6yB-5i6iA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_C_SAMC901_0 (MRNA CAPPING ENZYME P5)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	VAL A1920 GLY A1921 ASP A1979 ALA A1976 LEU A1911	None	0.85A	5x6yC-5i6iA: undetectable	5x6yC-5i6iA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_C_CHDC308_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	LEU A 879 PHE A 883 LEU A 860 PHE A 845	None	1.25A	5xdxC-5i6iA: undetectable 5xdxJ-5i6iA: undetectable	5xdxC-5i6iA: 7.86 5xdxJ-5i6iA: 2.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	LEU A 879 PHE A 883 LEU A 860 PHE A 845	None	1.22A	5xdxP-5i6iA: undetectable 5xdxW-5i6iA: undetectable	5xdxP-5i6iA: 7.86 5xdxW-5i6iA: 2.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA605_0 (ALPHA-AMYLASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 8	GLY A2070 ILE A2072 ASP A2139 ASP A2136 HIS A2138	None	1.23A	6ag0A-5i6iA: undetectable	6ag0A-5i6iA: 3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_C_ACRC605_0 (ALPHA-AMYLASE)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	5 / 8	GLY A2070 ILE A2072 ASP A2139 ASP A2136 HIS A2138	None	1.20A	6ag0C-5i6iA: undetectable	6ag0C-5i6iA: 3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5i6i	ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN,ACETYL-COA CARBOXYLASE-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A1870 PHE A2162 LEU A1901 PHE A1902	None	1.07A	6nmpC-5i6iA: undetectable 6nmpJ-5i6iA: undetectable	6nmpC-5i6iA: 7.86 6nmpJ-5i6iA: 2.27