SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i6s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 7 ILE A 159
THR A 139
GLN A 156
MET A 192
 None
 1.13A 1kglA-5i6sA:
undetectable		 1kglA-5i6sA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.32A 1kifA-5i6sA:
undetectable		 1kifA-5i6sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.32A 1kifB-5i6sA:
undetectable		 1kifB-5i6sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.32A 1kifC-5i6sA:
undetectable		 1kifC-5i6sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.32A 1kifD-5i6sA:
undetectable		 1kifD-5i6sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.32A 1kifE-5i6sA:
undetectable		 1kifE-5i6sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.32A 1kifF-5i6sA:
undetectable		 1kifF-5i6sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.32A 1kifG-5i6sA:
undetectable		 1kifG-5i6sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.32A 1kifH-5i6sA:
undetectable		 1kifH-5i6sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.36A 1ve9A-5i6sA:
undetectable		 1ve9A-5i6sA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.37A 2du8G-5i6sA:
undetectable		 2du8G-5i6sA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 5 TYR A 209
TYR A 293
ILE A 292
GLY A 214
 None
 1.36A 2du8J-5i6sA:
undetectable		 2du8J-5i6sA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		6 / 12 ASN A 141
GLU A 142
HIS A 207
TYR A 209
GLU A 249
TRP A 282
 None
 0.86A 2v3dA-5i6sA:
18.0		 2v3dA-5i6sA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		3 / 3 TRP A 237
VAL A 232
TRP A 185
 None
 1.28A 2xdcC-5i6sA:
undetectable
2xdcD-5i6sA:
undetectable		 2xdcC-5i6sA:
5.60
2xdcD-5i6sA:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		3 / 3 TRP A 237
VAL A 232
TRP A 185
 None
 1.23A 2xdcE-5i6sA:
undetectable
2xdcF-5i6sA:
undetectable		 2xdcE-5i6sA:
5.60
2xdcF-5i6sA:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		3 / 3 TRP A 237
VAL A 232
TRP A 185
 None
 1.30A 2y5mE-5i6sA:
undetectable
2y5mF-5i6sA:
undetectable		 2y5mE-5i6sA:
5.60
2y5mF-5i6sA:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		3 / 3 TRP A 237
VAL A 232
TRP A 185
 None
 1.29A 2y6nC-5i6sA:
undetectable
2y6nD-5i6sA:
undetectable		 2y6nC-5i6sA:
5.60
2y6nD-5i6sA:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		3 / 3 TRP A 237
VAL A 232
TRP A 185
 None
 1.29A 2y6nE-5i6sA:
undetectable
2y6nF-5i6sA:
undetectable		 2y6nE-5i6sA:
5.60
2y6nF-5i6sA:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		5 / 12 ARG A  58
GLU A 175
TYR A 209
ASN A 141
HIS A 102
 None
 1.46A 3bjmB-5i6sA:
undetectable		 3bjmB-5i6sA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		5 / 9 ARG A  65
VAL A  86
ILE A  46
GLY A 285
PRO A  60
 None
 1.24A 3el4B-5i6sA:
undetectable		 3el4B-5i6sA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 7 SER A 149
VAL A 151
ARG A 106
GLU A 148
 None
 1.43A 3n5tA-5i6sA:
undetectable
3n5tB-5i6sA:
undetectable		 3n5tA-5i6sA:
19.60
3n5tB-5i6sA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		5 / 11 GLY A 161
ALA A 157
ILE A 162
PHE A 121
ALA A 126
 None
 1.06A 3nmuB-5i6sA:
undetectable
3nmuJ-5i6sA:
undetectable		 3nmuB-5i6sA:
20.40
3nmuJ-5i6sA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		3 / 3 TRP A 237
VAL A 232
TRP A 185
 None
 0.80A 3zq8A-5i6sA:
undetectable
3zq8B-5i6sA:
undetectable		 3zq8A-5i6sA:
5.60
3zq8B-5i6sA:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		3 / 3 ASN A  19
TRP A 282
ASP A 138
 None
 1.29A 4a7tA-5i6sA:
undetectable
4a7tF-5i6sA:
undetectable		 4a7tA-5i6sA:
20.68
4a7tF-5i6sA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		3 / 3 ASP A 267
TRP A 281
SER A  12
 None
 1.04A 4lrhA-5i6sA:
undetectable		 4lrhA-5i6sA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 6 LEU A 154
ASN A 155
MET A  71
ILE A 172
 None
 1.10A 4okxA-5i6sA:
undetectable		 4okxA-5i6sA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 7 GLU A 148
SER A 149
VAL A 151
ARG A 106
 None
 1.45A 5adlA-5i6sA:
0.8
5adlB-5i6sA:
0.8		 5adlA-5i6sA:
19.60
5adlB-5i6sA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 7 GLU A 148
SER A 149
VAL A 151
ARG A 106
 None
 1.44A 5vv7A-5i6sA:
0.6
5vv7B-5i6sA:
0.9		 5vv7A-5i6sA:
19.60
5vv7B-5i6sA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 7 GLU A 148
SER A 149
VAL A 151
ARG A 106
 None
 1.46A 5vvnA-5i6sA:
undetectable
5vvnB-5i6sA:
undetectable		 5vvnA-5i6sA:
19.60
5vvnB-5i6sA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		5 / 12 PHE A 314
SER A  18
ILE A 246
LEU A 307
LEU A  49
 None
 1.42A 5ycpA-5i6sA:
undetectable		 5ycpA-5i6sA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		4 / 7 GLU A 148
SER A 149
VAL A 151
ARG A 106
 None
 1.44A 6av6C-5i6sA:
undetectable
6av6D-5i6sA:
undetectable		 6av6C-5i6sA:
13.95
6av6D-5i6sA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		5 / 11 ASP A 160
VAL A 152
GLY A 176
SER A 180
ALA A 182
 None
 1.20A 6hu9A-5i6sA:
undetectable
6hu9E-5i6sA:
undetectable
6hu9I-5i6sA:
undetectable		 6hu9A-5i6sA:
22.15
6hu9E-5i6sA:
19.81
6hu9I-5i6sA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		5 / 11 VAL A 152
GLY A 176
SER A 180
ALA A 182
VAL A 174
 None
 1.45A 6hu9A-5i6sA:
undetectable
6hu9E-5i6sA:
undetectable
6hu9I-5i6sA:
undetectable		 6hu9A-5i6sA:
22.15
6hu9E-5i6sA:
19.81
6hu9I-5i6sA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 5i6s ENDOGLUCANASE
(Talaromyces
verruculosus) 		5 / 12 TRP A 282
PHE A  57
ALA A 284
TYR A 291
VAL A  86
 None
 1.31A 6hu9N-5i6sA:
undetectable		 6hu9N-5i6sA:
19.50