SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i73'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 5i73 8B6 ANTIBODY, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 LEU B 163
VAL B 188
GLY B 182
VAL B 208
VAL B 206
 None
 0.87A 2ieoB-5i73B:
undetectable		 2ieoB-5i73B:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 5i73 8B6 ANTIBODY, HEAVY
CHAIN
(Mus
musculus) 		5 / 10 LEU B 163
VAL B 188
GLY B 182
VAL B 208
VAL B 206
 None
 1.08A 3nu9B-5i73B:
undetectable		 3nu9B-5i73B:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5i73 8B6 ANTIBODY, HEAVY
CHAIN
(Mus
musculus) 		3 / 3 TYR B 124
ARG B 117
SER B 118
 None
 1.15A 4dr2I-5i73B:
undetectable
4dr2J-5i73B:
undetectable		 4dr2I-5i73B:
18.83
4dr2J-5i73B:
16.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 5i73 8B6 ANTIBODY, HEAVY
CHAIN
(Mus
musculus) 		4 / 5 VAL B  21
TYR B  46
ARG B 117
TYR B 127
 None
 0.26A 4m7kH-5i73B:
26.6		 4m7kH-5i73B:
65.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 5i73 8B6 ANTIBODY, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 LEU B 102
GLY B  68
ASN B  69
ALA B  87
GLY B  76
 None
 1.20A 4n09A-5i73B:
undetectable		 4n09A-5i73B:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5i73 8B6 ANTIBODY, HEAVY
CHAIN
(Mus
musculus) 		3 / 3 SER B 228
ALA B 223
VAL B 222
 None
 0.53A 4x1iA-5i73B:
undetectable		 4x1iA-5i73B:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5i73 8B6 ANTIBODY, HEAVY
CHAIN
(Mus
musculus) 		3 / 3 SER B 228
ALA B 223
VAL B 222
 None
 0.50A 5eypA-5i73B:
undetectable		 5eypA-5i73B:
18.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 5i73 8B6 ANTIBODY, HEAVY
CHAIN
(Mus
musculus) 		4 / 5 SER B 137
ALA B 139
PHE B 171
LEU B 195
 None
 0.34A 5mthA-5i73B:
28.3		 5mthA-5i73B:
75.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5i73 8B6 ANTIBODY, HEAVY
CHAIN
(Mus
musculus) 		3 / 3 SER B 228
ALA B 223
VAL B 222
 None
 0.47A 5xiwC-5i73B:
undetectable		 5xiwC-5i73B:
16.29