SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 5i7z LD29223P
(Drosophila
melanogaster) 		5 / 9 LEU A 231
GLY A 179
VAL A 226
ILE A 197
THR A 235
 None
None
None
None
PEG  A 301 ( 4.2A)
 1.16A 4njtD-5i7zA:
undetectable		 4njtD-5i7zA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5i7z LD29223P
(Drosophila
melanogaster) 		4 / 6 LEU A 163
ARG A 159
ASP A 216
VAL A 234
 None
 1.00A 4nkxA-5i7zA:
undetectable		 4nkxA-5i7zA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 5i7z LD29223P
(Drosophila
melanogaster) 		5 / 12 ALA A 227
ARG A 177
ILE A 176
VAL A 218
ILE A 197
 None
 1.06A 4uw0A-5i7zA:
undetectable		 4uw0A-5i7zA:
11.83