SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 9 GLY A 214
PHE A 128
TYR A 217
TRP A 192
GLY A 195
 None
 1.43A 1acjA-5i84A:
undetectable		 1acjA-5i84A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 5 TYR A 217
SER A 163
SER A 166
ASN A 201
 None
 1.42A 1yvpA-5i84A:
undetectable		 1yvpA-5i84A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 8 ILE A  66
SER A  62
LEU A  83
GLU A  87
 PO4  A 404 (-4.2A)
None
None
None
 0.92A 2cdqA-5i84A:
undetectable		 2cdqA-5i84A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 9 ALA A 189
ALA A  81
GLY A 164
GLY A  63
ILE A  66
 None
None
None
PO4  A 403 ( 3.1A)
PO4  A 404 (-4.2A)
 1.22A 2v7bA-5i84A:
undetectable		 2v7bA-5i84A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 9 ALA A 189
ALA A  81
GLY A 164
GLY A  63
ILE A  66
 None
None
None
PO4  A 403 ( 3.1A)
PO4  A 404 (-4.2A)
 1.20A 2v7bB-5i84A:
undetectable		 2v7bB-5i84A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 6 ARG A 159
PRO A 243
GLY A 102
TRP A 276
 None
 1.48A 3aqiA-5i84A:
undetectable		 3aqiA-5i84A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 6 MET A 228
ARG A 159
PRO A 243
GLY A 102
 None
 1.35A 3aqiA-5i84A:
undetectable		 3aqiA-5i84A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 6 ARG A 159
PRO A 243
GLY A 102
TRP A 276
 None
 1.41A 3aqiB-5i84A:
undetectable		 3aqiB-5i84A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 6 MET A 228
ARG A 159
PRO A 243
GLY A 102
 None
 1.22A 3aqiB-5i84A:
undetectable		 3aqiB-5i84A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 8 PHE A  76
VAL A 286
VAL A  28
ILE A 330
 None
 0.74A 3hjoA-5i84A:
undetectable		 3hjoA-5i84A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 8 PHE A  76
VAL A 286
VAL A  28
ILE A 330
 None
 0.76A 3hjoB-5i84A:
undetectable		 3hjoB-5i84A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 6 TYR A  37
GLN A  58
SER A  44
SER A  41
 None
 1.23A 3pmzD-5i84A:
undetectable		 3pmzD-5i84A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 6 GLU A  86
LYS A  84
ASP A 262
TYR A 264
 None
 1.23A 3pocB-5i84A:
undetectable		 3pocB-5i84A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 12 GLN A  68
THR A 188
GLY A  61
GLY A 164
GLY A  32
 None
PO4  A 403 ( 4.6A)
None
None
None
 1.16A 3tegA-5i84A:
undetectable		 3tegA-5i84A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 12 ASP A  80
GLY A  61
LEU A 220
GLY A 101
PRO A  38
 None
 1.14A 4blvA-5i84A:
undetectable		 4blvA-5i84A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 12 ASP A  80
GLY A  61
SER A  62
LEU A 220
GLY A 101
 None
 0.99A 4blvB-5i84A:
undetectable		 4blvB-5i84A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 11 ILE A 215
LEU A 143
ASP A 126
GLY A 125
PHE A 128
 None
 1.44A 4foxF-5i84A:
undetectable		 4foxF-5i84A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_ACTA605_0
(SERUM ALBUMIN)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		3 / 3 LYS A 261
LYS A 288
ALA A  89
 None
 1.00A 4ot2A-5i84A:
undetectable		 4ot2A-5i84A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 6 PRO A  97
ILE A 100
VAL A  39
PHE A  35
 None
 1.12A 4xe5A-5i84A:
undetectable		 4xe5A-5i84A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		3 / 3 ASN A 201
SER A 163
SER A  62
 None
 0.78A 5gsnA-5i84A:
undetectable		 5gsnA-5i84A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 7 ILE A  66
GLY A  65
PHE A 263
ASP A  80
 PO4  A 404 (-4.2A)
None
None
None
 0.82A 5hieA-5i84A:
undetectable		 5hieA-5i84A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		4 / 8 THR A 188
TYR A 217
VAL A 204
GLY A 198
 PO4  A 403 ( 4.6A)
None
None
None
 1.00A 5nzyA-5i84A:
undetectable		 5nzyA-5i84A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 11 GLY A 216
SER A 221
LEU A 220
VAL A 103
THR A 231
 None
 1.14A 5o96A-5i84A:
undetectable
5o96B-5i84A:
undetectable		 5o96A-5i84A:
20.22
5o96B-5i84A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 9 ILE A 215
ASP A 126
GLY A 125
PHE A 128
ALA A 139
 None
 1.43A 5x66C-5i84A:
undetectable		 5x66C-5i84A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 5i84 PHOSPHATE-BINDING
PROTEIN PSTS
(Xanthomonas
citri) 		5 / 10 ILE A 215
ASP A 126
GLY A 125
PHE A 128
ALA A 139
 None
 1.45A 5x66D-5i84A:
undetectable		 5x66D-5i84A:
23.50