SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i99'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5i99 CONTACTIN-3
(Mus
musculus) 		5 / 10 ASP A 623
SER A 626
ILE A 681
GLY A 682
GLU A 620
 None
 1.27A 1mehA-5i99A:
undetectable		 1mehA-5i99A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5i99 CONTACTIN-3
(Mus
musculus) 		3 / 3 GLY A 779
TRP A 721
VAL A 707
 None
 0.76A 3n62B-5i99A:
undetectable		 3n62B-5i99A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5i99 CONTACTIN-3
(Mus
musculus) 		3 / 3 GLY A 779
TRP A 721
VAL A 707
 None
 0.77A 3n66B-5i99A:
undetectable		 3n66B-5i99A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5i99 CONTACTIN-3
(Mus
musculus) 		4 / 5 ASN A 679
PRO A 598
GLY A 596
ASP A 623
 None
 1.15A 4n48B-5i99A:
undetectable		 4n48B-5i99A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 5i99 CONTACTIN-3
(Mus
musculus) 		4 / 7 THR A 695
ALA A 614
LEU A 616
ILE A 609
 None
 0.78A 4ubsA-5i99A:
undetectable		 4ubsA-5i99A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 5i99 CONTACTIN-3
(Mus
musculus) 		3 / 3 GLY A 556
GLN A 522
LYS A 553
 None
 1.00A 5imsB-5i99A:
undetectable		 5imsB-5i99A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5i99 CONTACTIN-3
(Mus
musculus) 		3 / 3 GLY A 779
TRP A 721
VAL A 707
 None
 0.75A 5vuoB-5i99A:
undetectable		 5vuoB-5i99A:
20.53