SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 5i9g PENTATRICOPEPTIDE
REPEAT PROTEIN
DPPR-U8C2
(unidentified) 		5 / 12 PRO C  84
VAL C  51
ILE C 117
TYR C  89
ILE C  58
 None
 1.39A 3q5pA-5i9gC:
undetectable		 3q5pA-5i9gC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5i9g PENTATRICOPEPTIDE
REPEAT PROTEIN
DPPR-U8C2
(unidentified) 		4 / 7 GLU C 285
LEU C 281
LEU C 302
LEU C 306
 None
 0.81A 4wg0B-5i9gC:
undetectable
4wg0C-5i9gC:
undetectable		 4wg0B-5i9gC:
2.52
4wg0C-5i9gC:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 5i9g PENTATRICOPEPTIDE
REPEAT PROTEIN
DPPR-U8C2
(unidentified) 		5 / 9 ALA C 210
LEU C 236
GLY C 235
LEU C 232
GLU C 244
 None
 1.22A 5dqfA-5i9gC:
2.6		 5dqfA-5i9gC:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5i9g PENTATRICOPEPTIDE
REPEAT PROTEIN
DPPR-U8C2
(unidentified) 		5 / 12 THR C  91
GLY C  95
LEU C  61
LEU C  67
ALA C  70
 U  A  -3 ( 4.1A)
None
None
None
None
 1.02A 5l0zA-5i9gC:
undetectable		 5l0zA-5i9gC:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5i9g PENTATRICOPEPTIDE
REPEAT PROTEIN
DPPR-U8C2
(unidentified) 		5 / 12 THR C 126
GLY C 130
LEU C  96
LEU C 102
ALA C 105
 U  A  -2 ( 3.9A)
None
None
None
None
 0.99A 5l0zA-5i9gC:
undetectable		 5l0zA-5i9gC:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5i9g PENTATRICOPEPTIDE
REPEAT PROTEIN
DPPR-U8C2
(unidentified) 		5 / 12 THR C 266
GLY C 270
LEU C 236
LEU C 242
ALA C 245
 U  A   2 ( 3.9A)
None
None
None
None
 1.00A 5l0zA-5i9gC:
undetectable		 5l0zA-5i9gC:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 5i9g PENTATRICOPEPTIDE
REPEAT PROTEIN
DPPR-U8C2
(unidentified) 		5 / 12 ALA C 315
GLU C 349
LEU C 353
ILE C 338
ASP C 348
 None
 1.31A 5vlmG-5i9gC:
1.2		 5vlmG-5i9gC:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5i9g PENTATRICOPEPTIDE
REPEAT PROTEIN
DPPR-U8C2
(unidentified) 		3 / 3 LYS C 153
PRO C 154
LYS C 185
 None
 0.97A 5y9yA-5i9gC:
undetectable		 5y9yA-5i9gC:
22.10