SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5i9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JQD_A_HSMA600_1
(HISTAMINE
N-METHYLTRANSFERASE)		 5i9q 426C.TM4DV1-3 P120
(Human
immunodeficiency
virus
1) 		4 / 7 PHE A 210
VAL A 108
TRP A 112
TRP A 427
 None
None
None
EDO  A 606 (-4.7A)
 1.34A 1jqdA-5i9qA:
undetectable		 1jqdA-5i9qA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 5i9q 3BNC55 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 4 ALA B  40
ARG B  38
GLN B  43
GLU B  46
 None
 0.60A 1lqtB-5i9qB:
undetectable		 1lqtB-5i9qB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 5i9q 3BNC55 FAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 4 ALA B  40
ARG B  38
GLN B  43
GLU B  46
 None
 0.60A 1lquB-5i9qB:
undetectable		 1lquB-5i9qB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5i9q 426C.TM4DV1-3 P120
(Human
immunodeficiency
virus
1) 		5 / 12 LEU A 453
ILE A 272
ILE A 333
ILE A 449
LEU A 288
 None
 1.06A 1oipA-5i9qA:
undetectable		 1oipA-5i9qA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 5i9q 3BNC55 FAB HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 TRP B 103
PHE B 100
TRP B  37
 None
 1.30A 1r15C-5i9qB:
undetectable		 1r15C-5i9qB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 5i9q 3BNC55 FAB HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 TRP B 103
PHE B 100
TRP B  37
 None
 1.29A 1r15F-5i9qB:
undetectable		 1r15F-5i9qB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 5i9q 3BNC55 FAB HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 TRP B 103
PHE B 100
TRP B  37
 None
 1.31A 1r15G-5i9qB:
undetectable		 1r15G-5i9qB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 5i9q 3BNC55 FAB HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 TRP B 103
PHE B 100
TRP B  37
 None
 1.30A 1r15H-5i9qB:
undetectable		 1r15H-5i9qB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5i9q 426C.TM4DV1-3 P120
(Human
immunodeficiency
virus
1) 		3 / 3 THR A 123
ASN A 197
GLU A 429
 None
 0.70A 3v4tA-5i9qA:
undetectable
3v4tC-5i9qA:
undetectable		 3v4tA-5i9qA:
21.71
3v4tC-5i9qA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 5i9q 3BNC55 FAB HEAVY
CHAIN
426C.TM4DV1-3 P120
(Homo
sapiens;
Human
immunodeficiency
virus
1) 		4 / 7 ASP A 457
TYR B  59
PRO B  60
SER A 364
 None
 0.99A 5b6iA-5i9qA:
undetectable		 5b6iA-5i9qA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 5i9q 426C.TM4DV1-3 P120
(Human
immunodeficiency
virus
1) 		5 / 9 LEU A 259
LEU A 452
ILE A 394
LEU A 416
ALA A 341
 None
 1.31A 5og9A-5i9qA:
undetectable		 5og9A-5i9qA:
20.08