SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ibk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5ibk POLYUBIQUITIN-B
(Homo
sapiens) 		5 / 12 ILE F   3
THR F   7
PHE F  45
LEU F  43
ILE F  30
 None
 0.86A 2cd2A-5ibkF:
undetectable		 2cd2A-5ibkF:
21.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_A_DVAA35_0
(UBIQUITIN)		 5ibk POLYUBIQUITIN-B
(Homo
sapiens) 		4 / 4 GLN F  31
GLU F  34
ILE F  36
PRO F  37
 None
 0.91A 2fcnA-5ibkF:
15.4		 2fcnA-5ibkF:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5ibk POLYUBIQUITIN-B
(Homo
sapiens) 		4 / 6 GLN F  31
GLU F  34
ILE F  36
PRO F  37
 None
 0.36A 2fcnA-5ibkF:
15.4
2fcnB-5ibkF:
15.4		 2fcnA-5ibkF:
74.36
2fcnB-5ibkF:
74.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 5ibk POLYUBIQUITIN-B
(Homo
sapiens) 		3 / 3 ARG F  74
GLN F  31
PRO F  37
 None
 0.89A 2qhfA-5ibkF:
undetectable		 2qhfA-5ibkF:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5ibk F-BOX/WD
REPEAT-CONTAINING
PROTEIN 7
(Homo
sapiens) 		3 / 3 ALA B 315
ASN B 318
LEU B 319
 None
 0.38A 5i1pA-5ibkB:
undetectable		 5i1pA-5ibkB:
15.62