SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ibo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 6 LEU A 150
GLU A 140
THR A 159
LEU A 163
 None
 0.88A 1etb2-5iboA:
undetectable		 1etb2-5iboA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 6 ASP A 100
GLY A 101
THR A 103
PRO A 104
 None
 0.69A 1n4fA-5iboA:
undetectable		 1n4fA-5iboA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 8 LEU A 150
GLU A 140
THR A 159
LEU A 163
 None
 0.97A 1sn5C-5iboA:
undetectable		 1sn5C-5iboA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE509_0
(NAD-DEPENDENT
DEACETYLASE 2)		 5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 6 ASP A 121
GLU A 140
ARG A 141
LYS A 124
 None
 1.49A 1yc2A-5iboA:
undetectable
1yc2B-5iboA:
undetectable
1yc2E-5iboA:
undetectable		 1yc2A-5iboA:
20.52
1yc2B-5iboA:
20.52
1yc2E-5iboA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 7 VAL A 127
LEU A  97
PHE A 151
LEU A 149
 None
 0.96A 3qeoB-5iboA:
undetectable		 3qeoB-5iboA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 8 LEU A 150
GLU A 140
THR A 159
LEU A 163
 None
 0.93A 4ik6B-5iboA:
undetectable		 4ik6B-5iboA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 5 TYR A  62
GLY A  64
HIS A  87
ASP A  84
 None
 1.14A 6gh9A-5iboA:
undetectable		 6gh9A-5iboA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 7 SER A  47
THR A 103
ILE A 117
ALA A 118
 None
 0.86A 6ma7A-5iboA:
undetectable		 6ma7A-5iboA:
20.45