SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ibv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 ALA A 376
VAL A 369
TRP A 351
 None
 0.96A 1av2A-5ibvA:
undetectable
1av2B-5ibvA:
undetectable		 1av2A-5ibvA:
6.86
1av2B-5ibvA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 ARG A 179
ILE A 102
TRP A 350
 None
 0.99A 1m8eB-5ibvA:
undetectable		 1m8eB-5ibvA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 ARG A 179
ILE A 102
TRP A 350
 None
 1.08A 1nodB-5ibvA:
undetectable		 1nodB-5ibvA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 ARG A 179
ILE A 102
TRP A 350
 None
 1.18A 1qomA-5ibvA:
undetectable		 1qomA-5ibvA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 TRP A 351
ALA A 376
VAL A 369
 None
 0.97A 1w5uA-5ibvA:
undetectable
1w5uB-5ibvA:
undetectable		 1w5uA-5ibvA:
6.86
1w5uB-5ibvA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD6_0
(GRAMICIDIN D)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		4 / 4 TRP A 351
TRP A 324
ALA A 376
VAL A 353
 None
 1.22A 1w5uC-5ibvA:
undetectable
1w5uD-5ibvA:
undetectable		 1w5uC-5ibvA:
6.86
1w5uD-5ibvA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC6_0
(GRAMICIDIN D)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		4 / 4 ALA A 376
VAL A 353
TRP A 351
TRP A 324
 None
 1.26A 2izqC-5ibvA:
undetectable
2izqD-5ibvA:
undetectable		 2izqC-5ibvA:
6.86
2izqD-5ibvA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 ARG A 179
ILE A 102
TRP A 350
 None
 1.09A 2nodB-5ibvA:
undetectable		 2nodB-5ibvA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		4 / 5 LEU A 112
GLN A 406
THR A 405
THR A 209
 None
 1.10A 2zj0B-5ibvA:
undetectable		 2zj0B-5ibvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		4 / 5 LEU A 112
GLN A 406
THR A 405
THR A 218
 None
 1.28A 2zj0B-5ibvA:
undetectable		 2zj0B-5ibvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		4 / 5 LEU A 112
GLN A 406
THR A 405
THR A 218
 None
 1.26A 2zj0C-5ibvA:
undetectable		 2zj0C-5ibvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		4 / 4 LEU A 112
GLN A 406
THR A 405
THR A 218
 None
 1.25A 2zj0D-5ibvA:
undetectable		 2zj0D-5ibvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		4 / 5 LEU A 112
GLN A 406
THR A 405
THR A 218
 None
 1.28A 3ce6B-5ibvA:
undetectable		 3ce6B-5ibvA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 ARG A 179
ILE A 102
TRP A 350
 None
 0.96A 3e68A-5ibvA:
undetectable		 3e68A-5ibvA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 ARG A 179
ILE A 102
TRP A 350
 None
 1.00A 3e6tB-5ibvA:
undetectable		 3e6tB-5ibvA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 ARG A 179
ILE A 102
TRP A 350
 None
 1.13A 3e7iB-5ibvA:
undetectable		 3e7iB-5ibvA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 SER A 310
ASP A 321
ASN A 408
 None
 0.68A 3lsfB-5ibvA:
undetectable
3lsfE-5ibvA:
undetectable		 3lsfB-5ibvA:
21.36
3lsfE-5ibvA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		3 / 3 ASP A 321
ASN A 408
SER A 310
 None
 0.65A 3lsfB-5ibvA:
undetectable
3lsfE-5ibvA:
undetectable		 3lsfB-5ibvA:
21.36
3lsfE-5ibvA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ibv CAPSID POLYPROTEIN
VP90
(Mamastrovirus
1) 		4 / 7 ARG A 365
VAL A 277
PHE A 367
GLU A 280
 None
 1.48A 4jseA-5ibvA:
undetectable
4jseB-5ibvA:
undetectable		 4jseA-5ibvA:
22.82
4jseB-5ibvA:
22.82