SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ibx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK5_A_T44A1008_1
(SERUM ALBUMIN)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 10 ASP A 183
LYS A 186
VAL A 215
TYR A 223
VAL A 229
 None
None
None
None
CME  A 226 (-4.2A)
 1.40A 1hk5A-5ibxA:
2.1		 1hk5A-5ibxA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 12 ILE A 165
SER A 163
ILE A 126
CYH A 128
VAL A 144
 None
 1.25A 2ft9A-5ibxA:
undetectable		 2ft9A-5ibxA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 8 TYR A 211
ASP A 183
TYR A 167
TYR A 135
 None
 1.16A 2ha2A-5ibxA:
undetectable		 2ha2A-5ibxA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 11 ALA A 166
ALA A 232
GLY A 235
ILE A 125
HIS A  96
 None
 0.94A 2x1lA-5ibxA:
2.0		 2x1lA-5ibxA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 12 ALA A 166
ALA A 232
GLY A 235
ILE A 125
HIS A  96
 None
 0.89A 2x1lB-5ibxA:
undetectable		 2x1lB-5ibxA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 11 ALA A 166
ALA A 232
GLY A 235
ILE A 125
HIS A  96
 None
 0.92A 2x1lC-5ibxA:
undetectable		 2x1lC-5ibxA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 6 TYR A  91
PRO A 124
ARG A 208
PHE A 118
 None
 1.29A 4kf9A-5ibxA:
undetectable		 4kf9A-5ibxA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A 231
PHE A   6
GLY A  40
LEU A  60
VAL A 164
 None
 1.29A 5i71A-5ibxA:
undetectable		 5i71A-5ibxA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		3 / 3 PHE A 143
ARG A 100
ALA A 150
 None
 0.97A 6ecfB-5ibxA:
undetectable		 6ecfB-5ibxA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5ibx TRIOSEPHOSPHATE
ISOMERASE
(Streptococcus
pneumoniae) 		3 / 3 PHE A   6
ARG A 208
GLN A 210
 None
 1.01A 6g1pB-5ibxA:
undetectable		 6g1pB-5ibxA:
22.19