SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ibz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 5ibz UNCHARACTERIZED
PROTEIN
(uncultured
organism) 		5 / 12 ASP A 266
GLY A 223
GLY A 246
ILE A 196
ALA A 264
 None
 0.74A 1sguB-5ibzA:
undetectable		 1sguB-5ibzA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 5ibz UNCHARACTERIZED
PROTEIN
(uncultured
organism) 		5 / 10 ASP A 266
GLY A 223
GLY A 246
ILE A 196
ALA A 264
 None
 0.80A 1sh9B-5ibzA:
undetectable		 1sh9B-5ibzA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 5ibz UNCHARACTERIZED
PROTEIN
(uncultured
organism) 		4 / 8 LEU A 335
ALA A 339
LEU A 320
ILE A  77
 None
 0.73A 3cldB-5ibzA:
undetectable		 3cldB-5ibzA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5ibz UNCHARACTERIZED
PROTEIN
(uncultured
organism) 		5 / 12 GLY A 298
ASP A 266
ILE A 220
THR A 222
LEU A 270
 None
 1.26A 3iv6A-5ibzA:
undetectable		 3iv6A-5ibzA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 5ibz UNCHARACTERIZED
PROTEIN
(uncultured
organism) 		4 / 8 GLY A 287
LEU A 289
LEU A 290
ILE A 297
 None
 0.79A 3nbqB-5ibzA:
undetectable		 3nbqB-5ibzA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 5ibz UNCHARACTERIZED
PROTEIN
(uncultured
organism) 		4 / 8 GLY A 287
LEU A 289
LEU A 290
ILE A 297
 None
 0.79A 3nbqC-5ibzA:
undetectable		 3nbqC-5ibzA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5ibz UNCHARACTERIZED
PROTEIN
(uncultured
organism) 		5 / 12 VAL A  83
LEU A 126
GLN A 127
ILE A  75
ALA A  74
 None
 1.08A 4ltwA-5ibzA:
undetectable		 4ltwA-5ibzA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 5ibz UNCHARACTERIZED
PROTEIN
(uncultured
organism) 		3 / 3 PRO A 284
ASN A 288
HIS A  30
 None
 0.90A 4ma3H-5ibzA:
undetectable
4ma3L-5ibzA:
undetectable		 4ma3H-5ibzA:
20.95
4ma3L-5ibzA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 5ibz UNCHARACTERIZED
PROTEIN
(uncultured
organism) 		3 / 3 TYR A 229
GLY A  81
PRO A  82
 None
 0.41A 4qwpA-5ibzA:
undetectable		 4qwpA-5ibzA:
24.93