SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5icu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XF1_A_ACTA1107_0 (C5A PEPTIDASE)	5icu	COPC (Methylosinus trichosporium)	4 / 5	LEU A 102 GLY A 106 HIS A 107 ILE A 108	None None CU A 201 (-3.0A) None	0.97A	1xf1A-5icuA: 5.2	1xf1A-5icuA: 8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BWY_A_SAMA301_1 (COMT PROTEIN)	5icu	COPC (Methylosinus trichosporium)	3 / 3	SER A 24 GLU A 53 ASP A 105	None None CU A 201 (-2.5A)	0.84A	3bwyA-5icuA: undetectable	3bwyA-5icuA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N1T_W_CUW201_0 (COPC)	5icu	COPC (Methylosinus trichosporium)	3 / 3	HIS A 23 ASP A 105 HIS A 107	CU A 201 ( 3.1A) CU A 201 (-2.5A) CU A 201 (-3.0A)	0.30A	5n1tW-5icuA: 11.7	5n1tW-5icuA: 28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OS7_A_ACTA402_0 (CASEIN KINASE II SUBUNIT ALPHA)	5icu	COPC (Methylosinus trichosporium)	3 / 3	HIS A 107 SER A 103 LYS A 23	CU A 201 (-3.0A) None CU A 201 ( 4.2A)	1.40A	5os7A-5icuA: undetectable	5os7A-5icuA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GMD_B_ACTB402_0 (CASEIN KINASE II SUBUNIT ALPHA)	5icu	COPC (Methylosinus trichosporium)	3 / 3	HIS A 107 SER A 103 LYS A 23	CU A 201 (-3.0A) None CU A 201 ( 4.2A)	1.40A	6gmdB-5icuA: undetectable	6gmdB-5icuA: 16.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XF1_A_ACTA1107_0","C5A PEPTIDASE","5icu","COPC","Methylosinus trichosporium",4,"LEU A 102;GLY A 106;HIS A 107;ILE A 108","None;None; CU A 201 (-3.0A);None","0.97A","1xf1A-5icuA:5.2","1xf1A-5icuA:8.71"],["3BWY_A_SAMA301_1","COMT PROTEIN","5icu","COPC","Methylosinus trichosporium",3,"SER A  24;GLU A  53;ASP A 105","None;None; CU A 201 (-2.5A)","0.84A","3bwyA-5icuA:undetectable","3bwyA-5icuA:20.20"],["5N1T_W_CUW201_0","COPC","5icu","COPC","Methylosinus trichosporium",3,"HIS A  23;ASP A 105;HIS A 107"," CU A 201 ( 3.1A); CU A 201 (-2.5A); CU A 201 (-3.0A)","0.30A","5n1tW-5icuA:11.7","5n1tW-5icuA:28.46"],["5OS7_A_ACTA402_0","CASEIN KINASE II SUBUNIT ALPHA","5icu","COPC","Methylosinus trichosporium",3,"HIS A 107;SER A 103;LYS A  23"," CU A 201 (-3.0A);None; CU A 201 ( 4.2A)","1.40A","5os7A-5icuA:undetectable","5os7A-5icuA:16.67"],["6GMD_B_ACTB402_0","CASEIN KINASE II SUBUNIT ALPHA","5icu","COPC","Methylosinus trichosporium",3,"HIS A 107;SER A 103;LYS A  23"," CU A 201 (-3.0A);None; CU A 201 ( 4.2A)","1.40A","6gmdB-5icuA:undetectable","6gmdB-5icuA:16.67"]]