SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5id4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 12 ILE A 108
ILE A 107
ALA A 194
LEU A 183
ILE A 189
 None
 1.10A 1bsxA-5id4A:
undetectable		 1bsxA-5id4A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 12 ILE A 108
ILE A 107
ALA A 194
LEU A 183
ILE A 189
 None
 1.10A 1bsxB-5id4A:
undetectable		 1bsxB-5id4A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 10 LEU A 177
VAL A 125
ALA A 121
SER A 118
LEU A 150
 None
 1.11A 1pxxA-5id4A:
undetectable		 1pxxA-5id4A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 12 ILE A 108
ILE A 107
ALA A 194
LEU A 183
ILE A 189
 None
 1.00A 2h79A-5id4A:
undetectable		 2h79A-5id4A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 12 ILE A 108
ILE A 107
ALA A 194
LEU A 183
ILE A 189
 None
 0.99A 3gwsX-5id4A:
undetectable		 3gwsX-5id4A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 12 VAL A 206
ILE A 197
VAL A 215
LEU A  94
LEU A  76
 None
 1.05A 4m11B-5id4A:
1.0		 4m11B-5id4A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 9 ILE A 201
LEU A  93
VAL A 106
LEU A  76
ILE A  97
 None
 1.07A 4r38C-5id4A:
undetectable		 4r38C-5id4A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 12 ILE A 108
LEU A 143
GLY A  68
PHE A 136
THR A  98
 None
 1.18A 5byjA-5id4A:
undetectable		 5byjA-5id4A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 12 LEU A 177
VAL A 125
ALA A 121
SER A 118
LEU A 150
 None
 1.10A 5ikqA-5id4A:
undetectable		 5ikqA-5id4A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 12 LEU A 177
VAL A 125
ALA A 121
SER A 118
LEU A 150
 None
 1.13A 5ikqB-5id4A:
undetectable		 5ikqB-5id4A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		5 / 12 LEU A 187
ILE A 201
GLN A 218
ILE A  97
LEU A  94
 None
 0.99A 5y2tB-5id4A:
undetectable		 5y2tB-5id4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 5id4 DSBA-LIKE PROTEIN
(Proteus
mirabilis) 		4 / 8 LEU A  94
VAL A 215
LEU A 211
ILE A 214
 None
 0.92A 6cb4A-5id4A:
undetectable		 6cb4A-5id4A:
21.62