SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5idj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 9 ASN A 434
ASP A 479
ILE A 484
PRO A 485
ILE A 492
 ADP  A 600 ( 2.9A)
ADP  A 600 (-3.3A)
ADP  A 600 (-4.5A)
None
ADP  A 600 (-4.3A)
 1.00A 1aj6A-5idjA:
6.3		 1aj6A-5idjA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 6 ALA A 371
LYS A 368
ASP A 364
ALA A 363
LEU A 328
 None
 1.33A 1iwhA-5idjA:
undetectable		 1iwhA-5idjA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 12 ASN A 434
ASP A 479
ILE A 484
PRO A 485
ASP A 487
 ADP  A 600 ( 2.9A)
ADP  A 600 (-3.3A)
ADP  A 600 (-4.5A)
None
None
 1.25A 1kijB-5idjA:
6.6		 1kijB-5idjA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 12 ASN A 434
ASP A 479
ILE A 484
PRO A 485
ILE A 492
 ADP  A 600 ( 2.9A)
ADP  A 600 (-3.3A)
ADP  A 600 (-4.5A)
None
ADP  A 600 (-4.3A)
 1.14A 1kijB-5idjA:
6.6		 1kijB-5idjA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 12 PHE A 392
ILE A 516
VAL A 417
ILE A 389
ILE A 538
 None
 1.17A 1r5lA-5idjA:
undetectable		 1r5lA-5idjA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 7 ALA A 534
ASP A 479
GLY A 481
GLY A 483
PHE A 536
 ADP  A 600 (-3.4A)
ADP  A 600 (-3.3A)
None
ADP  A 600 ( 4.5A)
ADP  A 600 (-4.5A)
 1.42A 2c49B-5idjA:
undetectable		 2c49B-5idjA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 7 ALA A 534
ASP A 479
GLY A 533
GLY A 483
PHE A 536
 ADP  A 600 (-3.4A)
ADP  A 600 (-3.3A)
None
ADP  A 600 ( 4.5A)
ADP  A 600 (-4.5A)
 1.32A 2c49B-5idjA:
undetectable		 2c49B-5idjA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 11 LEU A 388
ILE A 475
THR A 408
ARG A 436
LEU A 396
 None
 1.36A 2v0mD-5idjA:
undetectable		 2v0mD-5idjA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		4 / 5 LEU A 463
GLY A 464
PHE A 539
PHE A 474
 None
 1.11A 3smtA-5idjA:
undetectable		 3smtA-5idjA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		4 / 6 THR A 472
ASP A 471
ARG A 454
LEU A 455
 None
 1.11A 5tdzA-5idjA:
undetectable		 5tdzA-5idjA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5idj CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 12 PHE A 536
LEU A 463
GLY A 464
VAL A 513
ILE A 524
 ADP  A 600 (-4.5A)
None
None
None
None
 1.32A 6bxnB-5idjA:
undetectable		 6bxnB-5idjA:
21.78