SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5idm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 9 ASN A 434
ASP A 479
ILE A 484
PRO A 485
ILE A 492
 MG  A 602 ( 2.6A)
ANP  A 601 (-3.5A)
ANP  A 601 (-4.5A)
None
ANP  A 601 ( 4.0A)
 0.92A 1aj6A-5idmA:
6.4		 1aj6A-5idmA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 12 ASP A 437
ASP A 479
ILE A 484
PRO A 485
ASP A 487
 None
ANP  A 601 (-3.5A)
ANP  A 601 (-4.5A)
None
None
 1.03A 1kijA-5idmA:
6.6		 1kijA-5idmA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 12 ASP A 479
ILE A 484
PRO A 485
ASP A 487
ILE A 492
 ANP  A 601 (-3.5A)
ANP  A 601 (-4.5A)
None
None
ANP  A 601 ( 4.0A)
 1.13A 1kijA-5idmA:
6.6		 1kijA-5idmA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		6 / 12 ASN A 434
ASP A 479
ILE A 484
PRO A 485
ASP A 487
ILE A 492
 MG  A 602 ( 2.6A)
ANP  A 601 (-3.5A)
ANP  A 601 (-4.5A)
None
None
ANP  A 601 ( 4.0A)
 1.32A 1kijB-5idmA:
6.6		 1kijB-5idmA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		6 / 12 ASN A 434
ASP A 437
ASP A 479
PRO A 485
ASP A 487
ILE A 492
 MG  A 602 ( 2.6A)
None
ANP  A 601 (-3.5A)
None
None
ANP  A 601 ( 4.0A)
 1.10A 1s14A-5idmA:
5.8		 1s14A-5idmA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		6 / 12 ASN A 434
ASP A 437
ASP A 479
PRO A 485
ASP A 487
ILE A 492
 MG  A 602 ( 2.6A)
None
ANP  A 601 (-3.5A)
None
None
ANP  A 601 ( 4.0A)
 1.11A 1s14B-5idmA:
5.7		 1s14B-5idmA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 7 ALA A 534
ASP A 479
GLY A 481
GLY A 483
PHE A 536
 ANP  A 601 ( 3.8A)
ANP  A 601 (-3.5A)
None
ANP  A 601 ( 4.5A)
ANP  A 601 ( 4.6A)
 1.33A 2c49B-5idmA:
undetectable		 2c49B-5idmA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		5 / 7 ALA A 534
ASP A 479
GLY A 533
GLY A 483
PHE A 536
 ANP  A 601 ( 3.8A)
ANP  A 601 (-3.5A)
None
ANP  A 601 ( 4.5A)
ANP  A 601 ( 4.6A)
 1.30A 2c49B-5idmA:
undetectable		 2c49B-5idmA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		6 / 12 ASN A 434
ASP A 437
ASP A 479
PRO A 485
ASP A 487
ILE A 492
 MG  A 602 ( 2.6A)
None
ANP  A 601 (-3.5A)
None
None
ANP  A 601 ( 4.0A)
 1.11A 3lpsA-5idmA:
6.0		 3lpsA-5idmA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		4 / 5 LEU A 463
GLY A 464
PHE A 539
PHE A 474
 None
 1.11A 3smtA-5idmA:
undetectable		 3smtA-5idmA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		3 / 3 ASP A 403
ARG A 401
ASP A 437
 None
 0.88A 4fp9C-5idmA:
undetectable		 4fp9C-5idmA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		6 / 12 ASN A 434
ASP A 479
ILE A 484
PRO A 485
ASP A 487
ILE A 492
 MG  A 602 ( 2.6A)
ANP  A 601 (-3.5A)
ANP  A 601 (-4.5A)
None
None
ANP  A 601 ( 4.0A)
 1.23A 4uroA-5idmA:
6.4		 4uroA-5idmA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		6 / 12 ASN A 434
ASP A 479
ILE A 484
PRO A 485
ASP A 487
ILE A 492
 MG  A 602 ( 2.6A)
ANP  A 601 (-3.5A)
ANP  A 601 (-4.5A)
None
None
ANP  A 601 ( 4.0A)
 1.29A 4uroB-5idmA:
6.3		 4uroB-5idmA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		6 / 12 ASN A 434
ASP A 479
ILE A 484
PRO A 485
ASP A 487
ILE A 492
 MG  A 602 ( 2.6A)
ANP  A 601 (-3.5A)
ANP  A 601 (-4.5A)
None
None
ANP  A 601 ( 4.0A)
 1.04A 4uroC-5idmA:
6.2		 4uroC-5idmA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		6 / 12 ASN A 434
ASP A 479
ILE A 484
PRO A 485
ASP A 487
ILE A 492
 MG  A 602 ( 2.6A)
ANP  A 601 (-3.5A)
ANP  A 601 (-4.5A)
None
None
ANP  A 601 ( 4.0A)
 1.20A 4uroD-5idmA:
6.3		 4uroD-5idmA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 5idm CELL CYCLE HISTIDINE
KINASE CCKA
(Caulobacter
vibrioides) 		4 / 6 THR A 472
ASP A 471
ARG A 454
LEU A 455
 None
 0.94A 5tdzA-5idmA:
undetectable		 5tdzA-5idmA:
16.67