SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5idq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		3 / 3 TRP A 176
TYR A 218
LEU A 223
 None
 1.00A 1kxhA-5idqA:
undetectable		 1kxhA-5idqA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		4 / 7 THR A 102
VAL A   7
GLY A   8
ASP A  52
 None
 0.84A 2a1mA-5idqA:
undetectable		 2a1mA-5idqA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		3 / 3 ARG A  22
ASP A  72
ASP A 120
 None
 0.89A 2ejtA-5idqA:
5.1		 2ejtA-5idqA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 10 ALA A  30
THR A  31
ALA A  32
ALA A  48
VAL A  28
 None
 0.88A 2f16K-5idqA:
undetectable
2f16L-5idqA:
undetectable		 2f16K-5idqA:
22.69
2f16L-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 10 ALA A  30
THR A  31
ALA A  48
VAL A  28
GLY A  14
 None
 0.88A 2f16K-5idqA:
undetectable
2f16L-5idqA:
undetectable		 2f16K-5idqA:
22.69
2f16L-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 10 ALA A  30
THR A  31
ALA A  32
ALA A  48
VAL A  28
 None
 0.88A 2f16Y-5idqA:
undetectable
2f16Z-5idqA:
undetectable		 2f16Y-5idqA:
22.69
2f16Z-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 10 ALA A  30
THR A  31
ALA A  48
VAL A  28
GLY A  14
 None
 0.88A 2f16Y-5idqA:
undetectable
2f16Z-5idqA:
undetectable		 2f16Y-5idqA:
22.69
2f16Z-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 11 ALA A  30
THR A  31
ALA A  48
VAL A  28
GLY A  14
 None
 0.81A 3mg0K-5idqA:
undetectable
3mg0L-5idqA:
undetectable		 3mg0K-5idqA:
22.69
3mg0L-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 12 ALA A  30
THR A  31
ALA A  48
VAL A  28
GLY A  14
 None
 0.87A 3mg0Y-5idqA:
undetectable
3mg0Z-5idqA:
undetectable		 3mg0Y-5idqA:
22.69
3mg0Z-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		4 / 6 THR A 102
GLY A 106
ILE A  59
LEU A  76
 None
 0.97A 4acbC-5idqA:
3.4		 4acbC-5idqA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		3 / 3 ARG A 131
HIS A 173
SER A 134
 None
 0.87A 4mjwA-5idqA:
4.1
4mjwB-5idqA:
undetectable		 4mjwA-5idqA:
19.60
4mjwB-5idqA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		3 / 3 SER A 134
ARG A 131
HIS A 173
 None
 0.91A 4mjwA-5idqA:
4.1
4mjwB-5idqA:
undetectable		 4mjwA-5idqA:
19.60
4mjwB-5idqA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 10 ALA A  30
THR A  31
ALA A  32
ALA A  48
VAL A  28
 None
 0.88A 4qvyK-5idqA:
undetectable
4qvyL-5idqA:
undetectable		 4qvyK-5idqA:
22.69
4qvyL-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 10 ALA A  30
THR A  31
ALA A  48
VAL A  28
GLY A  14
 None
 0.85A 4qvyK-5idqA:
undetectable
4qvyL-5idqA:
undetectable		 4qvyK-5idqA:
22.69
4qvyL-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 10 ALA A  30
THR A  31
ALA A  32
ALA A  48
VAL A  28
 None
 0.87A 4qvyY-5idqA:
undetectable
4qvyZ-5idqA:
undetectable		 4qvyY-5idqA:
22.69
4qvyZ-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		5 / 10 ALA A  30
THR A  31
ALA A  48
VAL A  28
GLY A  14
 None
 0.85A 4qvyY-5idqA:
undetectable
4qvyZ-5idqA:
undetectable		 4qvyY-5idqA:
22.69
4qvyZ-5idqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		4 / 6 ILE A  29
ALA A  32
THR A  31
VAL A  18
 None
 0.90A 5eclD-5idqA:
undetectable		 5eclD-5idqA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		4 / 4 VAL A 200
GLU A 203
GLY A 220
LEU A 216
 None
 1.06A 5g5gC-5idqA:
undetectable		 5g5gC-5idqA:
15.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WQP_A_NCAA302_0
(PROBABLE
DEHYDROGENASE)		 5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR
(Burkholderia
vietnamiensis) 		4 / 8 SER A 130
MET A 132
TYR A 146
HIS A 173
 None
 0.76A 5wqpA-5idqA:
28.5		 5wqpA-5idqA:
34.85