SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5idt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 10 GLY A 175
PHE A 136
PHE A 119
THR A  43
LEU A  44
 None
 1.30A 1a8uA-5idtA:
undetectable		 1a8uA-5idtA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 10 GLY A 175
PHE A 136
PHE A 119
THR A  43
LEU A  44
 None
 1.35A 1a8uB-5idtA:
undetectable		 1a8uB-5idtA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 9 THR A  43
LEU A 123
ALA A 106
TYR A 179
LEU A 107
 None
 1.36A 2azqA-5idtA:
undetectable		 2azqA-5idtA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  89
LEU A 107
GLY A 110
ASP A 111
ALA A  10
 None
None
None
THM  A 301 (-3.1A)
None
 1.07A 2bm9F-5idtA:
undetectable		 2bm9F-5idtA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  89
LEU A 107
GLY A 110
ASP A 111
ALA A  10
 None
None
None
THM  A 301 (-3.1A)
None
 0.95A 2br4D-5idtA:
undetectable		 2br4D-5idtA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 11 GLY A 110
ILE A  37
PRO A  40
THR A  43
LYS A 250
 None
 1.30A 3bjwH-5idtA:
undetectable		 3bjwH-5idtA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A 201
LYS A  26
GLU A 199
 None
THM  A 301 ( 3.8A)
None
 1.02A 3ijdB-5idtA:
undetectable		 3ijdB-5idtA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 9 ALA A 187
ILE A 100
GLY A  96
ILE A  95
LEU A  89
 None
 1.09A 3u7sA-5idtA:
undetectable		 3u7sA-5idtA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 9 LEU A 107
ILE A   7
ILE A   8
TYR A  38
ILE A  55
 None
 0.92A 3zosA-5idtA:
undetectable		 3zosA-5idtA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 GLU A 162
LEU A 198
GLY A  88
VAL A 190
ALA A 187
 None
EDO  A 302 (-4.6A)
THM  A 301 (-3.5A)
None
None
 1.06A 4fqsA-5idtA:
undetectable		 4fqsA-5idtA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 GLU A 162
LEU A 198
GLY A  88
VAL A 190
ALA A 187
 None
EDO  A 302 (-4.6A)
THM  A 301 (-3.5A)
None
None
 1.08A 4fqsB-5idtA:
undetectable		 4fqsB-5idtA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 SER A 169
SER A 159
GLU A 199
TYR A 146
GLY A 147
 None
 1.34A 4qb9E-5idtA:
undetectable		 4qb9E-5idtA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  28
LEU A  68
GLY A  11
ALA A  10
SER A  56
 None
None
THM  A 301 (-2.9A)
None
None
 1.06A 5jvzA-5idtA:
undetectable		 5jvzA-5idtA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  28
LEU A  68
GLY A  11
ALA A  10
SER A  56
 None
None
THM  A 301 (-2.9A)
None
None
 1.01A 5jvzB-5idtA:
undetectable		 5jvzB-5idtA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_B_ACRB1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 9 PHE A 178
THR A 134
TYR A 177
GLY A 147
TYR A 146
 None
 1.45A 5lrbB-5idtA:
0.0		 5lrbB-5idtA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5P9I_A_1E8A701_2
(TYROSINE-PROTEIN
KINASE BTK)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		4 / 5 LEU A 249
TYR A 115
CYH A 253
ASP A  33
 None
 1.16A 5p9iA-5idtA:
undetectable		 5p9iA-5idtA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		4 / 5 GLY A 101
GLN A 181
VAL A 184
SER A 105
 None
 1.24A 5vunA-5idtA:
undetectable		 5vunA-5idtA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5idt GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 9 GLN A  91
GLN A  83
ASP A 111
GLY A 196
SER A 193
 EDO  A 302 (-3.5A)
THM  A 301 (-3.1A)
THM  A 301 (-3.1A)
None
None
 1.23A 5x7pA-5idtA:
0.5		 5x7pA-5idtA:
13.57